MEDICAMENT
    3.
    发明申请
    MEDICAMENT 审中-公开
    药物

    公开(公告)号:US20130203669A1

    公开(公告)日:2013-08-08

    申请号:US13544413

    申请日:2012-07-09

    申请人: Aimsco Limited

    发明人: Deirdre McIntosh

    IPC分类号: A61K38/22 A61K38/33

    摘要: Analysis of a goat serum product with many therapeutic effects is described. The product is identified as containing proopiomelanocortin (POMC) and Corticotropin releasing factor (CRF) peptides, as well as breakdown products of these peptides. We describe methods of treatment of diseases including cancers, multiple sclerosis, and neural disorders using these peptides and their products, as well as medicaments including such peptides and methods of producing the peptides.

    摘要翻译: 描述了具有许多治疗效果的山羊血清产物的分析。 该产物被鉴定为含有促皮质素皮质素(POMC)和促皮质激素释放因子(CRF)肽,以及这些肽的分解产物。 我们描述了使用这些肽及其产物的包括癌症,多发性硬化和神经障碍在内的疾病的治疗方法,以及包括这些肽的药物和生产肽的方法。

    TREATMENT OF DISEASES
    5.
    发明申请
    TREATMENT OF DISEASES 审中-公开
    治疗疾病

    公开(公告)号:US20140105998A1

    公开(公告)日:2014-04-17

    申请号:US14141347

    申请日:2013-12-26

    申请人: AIMSCO Limited

    发明人: Bryan Youl

    IPC分类号: A61K35/16

    摘要: Methods of treatment of various non-demyelinating and demyelinating neural disorders are provided, comprising administering a serum composition obtained from a goat after challenge with an immunogen. Also provided are methods of treatment of certain autommune disorders using such a composition.

    摘要翻译: 提供了治疗各种非脱髓鞘和脱髓鞘神经障碍的方法,包括用免疫原施用从攻击后的山羊获得的血清组合物。 还提供了使用这样的组合物治疗某些自身紊乱的方法。

    TREATMENT OF DISEASES
    8.
    发明申请
    TREATMENT OF DISEASES 审中-公开
    治疗疾病

    公开(公告)号:US20160101131A1

    公开(公告)日:2016-04-14

    申请号:US14968889

    申请日:2015-12-14

    申请人: AIMSCO Limited

    发明人: Bryan Youl

    IPC分类号: A61K35/16 A61K9/00

    摘要: Provided are methods for the treatment of various neural disorders including non-demyelinating neural disorders, such as Alzheimer's disease, as well as methods for the treatment of various autoimmune or immune-mediated disorders, such as scleroderma. Also provided are methods for restoring or improving one or more nerve functions, such as neural transmission, in a human with a neural disorder, such as a non-demyelinating neural disorder. Each of these methods comprise the administration of a serum composition obtained from a goat after challenge with an immunogen, in particular HIV or a lysate thereof.

    摘要翻译: 提供了用于治疗各种神经障碍的方法,包括非脱髓鞘性神经障碍,例如阿尔茨海默病,以及治疗各种自身免疫或免疫介导的疾病如硬皮病的方法。 还提供了用于在具有神经障碍(例如非脱髓鞘性神经障碍)的人中恢复或改善一种或多种神经功能(例如神经传递)的方法。 这些方法中的每一种包括在用免疫原特别是HIV或其裂解物攻击后从山羊获得的血清组合物的施用。