公开(公告)号：US20130142730A1

公开(公告)日：2013-06-06

申请号：US13676929

申请日：2012-11-14

Applicant: ZIOPHARM Oncology, Inc.

Inventor： Paul GUTSCH ,  Brian RENZELMANN

IPC: A61K45/06 ,  A61K31/285 ,  C07F9/72

CPC classification number: A61K45/06 ,  A61K31/285 ,  C07F9/72

Abstract: The present invention provides organic arsenicals. Many of these compounds have potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia.

Abstract translation: 本发明提供有机砷。 许多这些化合物对许多人类肿瘤细胞系（包括固体和血液来源）以及来自患有白血病的患者的恶性血细胞具有有效的体外细胞毒活性。