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公开(公告)号：USD660967S1
公开(公告)日：2012-05-29
申请号：US29375253
申请日：2010-09-20
CPC分类号： A61F2/91 , A61F2230/005 , A61F2230/0054 , A61F2230/008
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公开(公告)号：US09039759B2
公开(公告)日：2015-05-26
申请号：US13215901
申请日：2011-08-23
CPC分类号： A61F2/2436 , A61F2/24 , A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/243 , A61F2/2472 , A61F2002/9517 , A61F2002/9534 , A61F2220/005 , A61F2220/0066 , A61F2220/0075 , A61F2230/0013 , A61F2230/0021 , A61F2230/0054 , A61F2230/008 , A61F2240/008 , A61F2250/0039
摘要： A collapsible prosthetic heart valve includes a stent and a valve assembly. The stent has an annulus section with a relatively small cross-section, and an aortic section with a relatively large cross-section. The valve assembly, including a cuff and a plurality of leaflets, is secured to the stent in the annulus section such that the valve assembly can be entirely deployed in the native valve annulus and function as intended while at least a portion of the aortic section is held by the delivery device in a manner that allows for resheathing. The configuration of the prosthetic valve is such that the valve leaflets can fully coapt and the valve can function properly even when the stent and/or valve assembly become distorted upon deployment or use.
摘要翻译： 可折叠假体心脏瓣膜包括支架和阀组件。 支架具有横截面相对较小的环形部分和具有相对较大横截面的主动脉部分。 包括袖带和多个小叶的阀组件在环形部分中固定到支架，使得阀组件可以完全展开在天然瓣膜环中并按照预期的方式起作用，而主动脉部分的至少一部分是 由输送装置以允许再感染的方式保持。 假体瓣膜的构造使得即使当展开和/或瓣膜组件在展开或使用时变形时，瓣膜小叶片也可以完全适应并且阀门可正常工作。
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公开(公告)号：USD660433S1
公开(公告)日：2012-05-22
申请号：US29375257
申请日：2010-09-20
申请人： Peter Nicholas Braido , Thomas Mark Benson , Yousef F. Alkhatib , Aaron J. Chalekian , Jacob John Daly , Peter J. Ness
设计人： Peter Nicholas Braido , Thomas Mark Benson , Yousef F. Alkhatib , Aaron J. Chalekian , Jacob John Daly , Peter J. Ness
CPC分类号： A61F2/91 , A61F2230/005 , A61F2230/0054 , A61F2230/008
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公开(公告)号：US08932343B2
公开(公告)日：2015-01-13
申请号：US13215893
申请日：2011-08-23
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2002/9517 , A61F2002/9534 , A61F2220/0075 , A61F2230/0013 , A61F2250/0039
摘要： A collapsible prosthetic heart valve includes a stent and a valve assembly. The stent has a proximal end and a distal end and includes a plurality of struts. The struts have free ends configured to inhibit tissue penetration. The valve assembly, including a plurality of leaflets, is disposed within the stent.
摘要翻译： 可折叠假体心脏瓣膜包括支架和阀组件。 支架具有近端和远端，并且包括多个支柱。 支柱具有构造成抑制组织穿透的自由端。 包括多个小叶的阀组件设置在支架内。
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公开(公告)号：US20120197390A1
公开(公告)日：2012-08-02
申请号：US13215893
申请日：2011-08-23
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2002/9517 , A61F2002/9534 , A61F2220/0075 , A61F2230/0013 , A61F2250/0039
摘要： A collapsible prosthetic heart valve includes a stent and a valve assembly. The stent has a proximal end and a distal end and includes a plurality of struts. The struts have free ends configured to inhibit tissue penetration. The valve assembly, including a plurality of leaflets, is disposed within the stent.
摘要翻译： 可折叠假体心脏瓣膜包括支架和阀组件。 支架具有近端和远端，并且包括多个支柱。 支柱具有构造成抑制组织穿透的自由端。 包括多个小叶的阀组件设置在支架内。
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公开(公告)号：US20120053681A1
公开(公告)日：2012-03-01
申请号：US13215901
申请日：2011-08-23
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/24 , A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/243 , A61F2/2472 , A61F2002/9517 , A61F2002/9534 , A61F2220/005 , A61F2220/0066 , A61F2220/0075 , A61F2230/0013 , A61F2230/0021 , A61F2230/0054 , A61F2230/008 , A61F2240/008 , A61F2250/0039
摘要： A collapsible prosthetic heart valve includes a stent and a valve assembly. The stent has an annulus section with a relatively small cross-section, and an aortic section with a relatively large cross-section. The valve assembly, including a cuff and a plurality of leaflets, is secured to the stent in the annulus section such that the valve assembly can be entirely deployed in the native valve annulus and function as intended while at least a portion of the aortic section is held by the delivery device in a manner that allows for resheathing. The configuration of the prosthetic valve is such that the valve leaflets can fully coapt and the valve can function properly even when the stent and/or valve assembly become distorted upon deployment or use.
摘要翻译： 可折叠假体心脏瓣膜包括支架和阀组件。 支架具有横截面相对较小的环形部分和具有相对较大横截面的主动脉部分。 包括袖带和多个小叶的阀组件在环形部分中固定到支架，使得阀组件可以完全展开在天然瓣膜环中并按照预期的方式起作用，而主动脉部分的至少一部分是 由输送装置以允许再感染的方式保持。 假体瓣膜的构造使得即使当展开和/或瓣膜组件在展开或使用时变形时，瓣膜小叶片也可以完全适应并且阀门可正常工作。
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公开(公告)号：US09021674B2
公开(公告)日：2015-05-05
申请号：US13364501
申请日：2012-02-02
申请人： Brett Allen Hillukka , Huisun Wang , Valerie J. Glazier , Yousef F. Alkhatib , Jacob John Daly , Ralph Joseph Thomas
发明人： Brett Allen Hillukka , Huisun Wang , Valerie J. Glazier , Yousef F. Alkhatib , Jacob John Daly , Ralph Joseph Thomas
CPC分类号： A61F2/2427 , A61F2/0095 , A61F2/2412 , A61F2/2436 , A61F2/97 , A61F2002/9522 , A61F2250/0039 , Y10T29/49826 , Y10T29/53909 , Y10T29/53943
摘要： An assembly for collapsing a self-expanding prosthetic heart valve includes a compression member, a support member and a constricting member. The compression member has a tapered wall between its first open end and its second open end, the tapered wall defining an open space adapted to receive the valve. The support member has a base and a recess adapted to receive an end of the valve. The support member and the compression member are movable toward one another to compress the valve and push it through a relatively small aperture in the second open end of the compression member. The second end of the constricting member is sized to receive the compressed valve from the second open end of the compression member for loading into a delivery device.
摘要翻译： 用于塌缩自膨胀假体心脏瓣膜的组件包括压缩构件，支撑构件和收缩构件。 压缩构件在其第一开口端和其第二开口端之间具有锥形壁，锥形壁限定适于接收阀的开放空间。 支撑构件具有适于容纳阀的端部的基部和凹部。 支撑构件和压缩构件可彼此移动以压缩阀并将其推压通过压缩构件的第二开口端中的相对小的孔。 收缩构件的第二端的尺寸被设计成从压缩构件的第二开口端接收压缩的阀，用于装载到输送装置中。
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公开(公告)号：US08728154B2
公开(公告)日：2014-05-20
申请号：US12733344
申请日：2008-08-21
申请人： Yousef F. Alkhatib
发明人： Yousef F. Alkhatib
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2/2445 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054 , A61F2230/0076
摘要： A prosthetic aortic valve includes an annular, annulus inflow portion that is designed to reside in or near the patient's native aortic valve annulus, and an annular, aortic outflow portion that is designed to reside in the patient's aorta downstream from at least a portion of the valsalva sinus. The annulus inflow portion and the aortic outflow portion are connected to one another by a plurality of connecting struts that are confined to regions near the commissures of the patient's native aortic valve. The connecting struts are designed to bulge out into the valsalva sinus to help anchor the prosthetic valve in place. The valve is circumferentially collapsible to a relatively small diameter for less-invasive delivery into the patient. The valve circumferentially expands to a larger operational diameter when deployed at the implant site.
摘要翻译： 假体主动脉瓣包括环形环形流入部分，其被设计为驻留在患者的天然主动脉瓣膜环内或附近，以及环形主动脉流出部分，其被设计为驻留在患者主动脉中的至少一部分 valsalva窦。 环形流入部分和主动脉流出部分通过多个连接支柱彼此连接，所述多个连接支柱被限制在靠近病人天然主动脉瓣的连合处的区域。 连接支柱被设计成凸出到瓦尔萨瓦窦中，以帮助将假肢瓣锚定到位。 瓣膜周向可折叠到相对较小的直径，用于较少侵入性地输送到患者体内。 当部署在植入部位时，阀周向地膨胀到更大的操作直径。
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9.发明授权Apparatus and method for implanting collapsible/expandable prosthetic heart valves 有权用于植入可折叠/可扩张的假体心脏瓣膜的装置和方法公开(公告)号：US08512398B2
公开(公告)日：2013-08-20
申请号：US12452128
申请日：2008-06-26
申请人： Yousef F. Alkhatib
发明人： Yousef F. Alkhatib
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/013 , A61F2/24 , A61F2/2418 , A61F2/2439 , A61F2002/016 , A61F2002/018 , A61F2002/9517 , A61F2230/0071 , A61F2230/008 , A61F2230/0093
摘要： Apparatus for delivering a prosthetic heart valve into a patient by means that are less invasive than conventional open-chest, open-heart surgery. The prosthetic valve may be collapsed while in a delivery device. When the valve reaches the desired implant site in the patient, the valve can be released from the delivery device, which allows the valve to re-expand to the configuration in which it can function as a heart valve. For example, the delivery device may be constructed to facilitate delivery of the prosthetic valve into the patient via the apex of the patient's heart.
摘要翻译： 用于将假体心脏瓣膜输送到患者体内的装置，其方式是比传统的胸腔开放心脏手术侵入性较差。 假体瓣膜可能在输送装置中折叠。 当阀门到达病人所需的植入部位时，阀门可以从输送装置中释放出来，这样可以使阀门重新膨胀到其可用作心脏瓣膜的结构。 例如，输送装置可以构造成便于经由患者心脏的顶点将假体瓣膜输送到患者体内。
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10.发明申请APPARATUS AND METHOD FOR IMPLANTING COLLAPSIBLE/EXPANDABLE PROSTHETIC HEART VALVES 有权用于植入可膨胀/可扩展的前置心脏瓣膜的装置和方法公开(公告)号：US20100191326A1
公开(公告)日：2010-07-29
申请号：US12452128
申请日：2008-06-26
申请人： Yousef F. Alkhatib
发明人： Yousef F. Alkhatib
CPC分类号： A61F2/2436 , A61F2/013 , A61F2/24 , A61F2/2418 , A61F2/2439 , A61F2002/016 , A61F2002/018 , A61F2002/9517 , A61F2230/0071 , A61F2230/008 , A61F2230/0093
摘要： Apparatus for delivering a prosthetic heart valve into a patient by means that are less invasive than conventional open-chest, open-heart surgery. The prosthetic valve may be collapsed while in a delivery device. When the valve reaches the desired implant site in the patient, the valve can be released from the delivery device, which allows the valve to re-expand to the configuration in which it can function as a heart valve. For example, the delivery device may be constructed to facilitate delivery of the prosthetic valve into the patient via the apex of the patient's heart.
摘要翻译： 用于将假体心脏瓣膜输送到患者体内的装置，其方式是比传统的胸腔开放心脏手术侵入性较差。 假体瓣膜可能在输送装置中折叠。 当阀门到达病人所需的植入部位时，阀门可以从输送装置中释放出来，这样可以使阀门重新膨胀到其可用作心脏瓣膜的结构。 例如，输送装置可以构造成便于经由患者心脏的顶点将假体瓣膜输送到患者体内。
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