公开(公告)号：US08049179B2

公开(公告)日：2011-11-01

申请号：US12443829

申请日：2007-10-03

申请人： Yoshimasa Miura ,  Yoshihiro Takiguchi ,  Masayuki Shirao ,  Sadaki Takata ,  Masato Hatao ,  Hiroshi Fukui

发明人： Yoshimasa Miura ,  Yoshihiro Takiguchi ,  Masayuki Shirao ,  Sadaki Takata ,  Masato Hatao ,  Hiroshi Fukui

IPC分类号： G01J1/02

CPC分类号： G01J1/429 ,  A61B5/0059 ,  A61B5/0075 ,  A61B5/441 ,  A61B5/445 ,  G01J3/42 ,  G01N21/33

摘要： An ultraviolet radiation detector 10, detecting an ultraviolet radiation transmitted through or reflected from a measurement sample 15 from a light beam including at least the ultraviolet radiation, is characterized by spectral means 19 for spectrally splitting the ultraviolet radiation from the light beam and photodetection means 20 for detecting the ultraviolet radiation spectrally split by the spectral means 19, the photodetection means 20 including a photoelectric surface detecting only the ultraviolet radiation and formed of an element selected from In, Ga, N, Al, O and Cs.

摘要翻译： 检测从至少包括紫外线辐射的光束透过或从测量样品15反射的紫外线辐射的紫外线辐射检测器10的特征在于用于光谱分解来自光束的紫外线辐射的光谱装置19和光电检测装置20 为了检测由光谱装置19光谱分割的紫外线辐射，光检测装置20包括仅检测紫外线并由选自In，Ga，N，Al，O和Cs的元素形成的光电表面。

公开(公告)号：US20100012850A1

公开(公告)日：2010-01-21

申请号：US12443829

申请日：2007-10-03

申请人： Yoshimasa Miura ,  Yoshihiro Takiguchi ,  Masayuki Shirao ,  Sadaki Takata ,  Masato Hatao ,  Hiroshi Fukui

发明人： Yoshimasa Miura ,  Yoshihiro Takiguchi ,  Masayuki Shirao ,  Sadaki Takata ,  Masato Hatao ,  Hiroshi Fukui

IPC分类号： G01J1/42

CPC分类号： G01J1/429 ,  A61B5/0059 ,  A61B5/0075 ,  A61B5/441 ,  A61B5/445 ,  G01J3/42 ,  G01N21/33

摘要： An ultraviolet radiation detector 10, detecting an ultraviolet radiation transmitted through or reflected from a measurement sample 15 from a light beam including at least the ultraviolet radiation, is characterized by spectral means 19 for spectrally splitting the ultraviolet radiation from the light beam and photodetection means 20 for detecting the ultraviolet radiation spectrally split by the spectral means 19, the photodetection means 20 including a photoelectric surface detecting only the ultraviolet radiation and formed of an element selected from In, Ga, N, Al, O and Cs.

摘要翻译： 检测从至少包括紫外线辐射的光束透过或从测量样品15反射的紫外线辐射的紫外线辐射检测器10的特征在于用于光谱分解来自光束的紫外线辐射的光谱装置19和光电检测装置20 为了检测由光谱装置19光谱分割的紫外线辐射，光检测装置20包括仅检测紫外线并由选自In，Ga，N，Al，O和Cs的元素形成的光电表面。

公开(公告)号：US20110098815A1

公开(公告)日：2011-04-28

申请号：US12996859

申请日：2009-03-24

申请人： Yoshimasa Miura ,  Hiroko Mizuno ,  Masato Hatao ,  Motoki Ooguri ,  Yusuke Hara

发明人： Yoshimasa Miura ,  Hiroko Mizuno ,  Masato Hatao ,  Motoki Ooguri ,  Yusuke Hara

IPC分类号： A61F2/10

CPC分类号： G01N33/5082

摘要： A skin substitute membrane includes a surface on one side including a groove-shaped depressed portion and a planar portion, the depressed portion having a cross section having a chamfered V-letter shape, the surface having an arithmetic mean roughness Sa of more than or equal to 10 μm to less than or equal to 50 μm. The depressed portion has a width of more than or equal to 50 μm to less than or equal to 500 μm and a depth of more than or equal to 30 μm to less than or equal to 150 μm. A spectral transmittance for light of more than or equal to 290 nm to less than or equal to 400 nm in wavelength is more than or equal to 50% and less than or equal to 100%.

摘要翻译： 皮肤替代膜包括在一侧的包括凹槽状凹部和平面部的表面，所述凹部具有倒角V字形的横截面，所述表面的算术平均粗糙度Sa大于或等于 至10μm至小于或等于50μm。 凹陷部具有大于或等于50μm至小于或等于500μm的宽度和大于或等于30μm至小于或等于150μm的深度。 对于波长大于或等于290nm至小于或等于400nm的光的光谱透射率大于或等于50％且小于或等于100％。

公开(公告)号：US07937227B2

公开(公告)日：2011-05-03

申请号：US12682286

申请日：2008-10-17

申请人： Yoshimasa Miura ,  Masato Hatao

发明人： Yoshimasa Miura ,  Masato Hatao

IPC分类号： G06F17/40 ,  G06F17/00

CPC分类号： G01N21/33

摘要： A method and apparatus for evaluating an ultraviolet radiation protection effect in a measurement sample is used for evaluating SPF (Sun Protection Factor). First, a temporal change of the spectral transmission spectrum in the measurement sample within a predetermined light wavelength range at predetermined wavelength intervals is measured. Second, a correlation between a light irradiating time and minimal erythema doses by predetermined lime intervals based on the temporal change of the spectral transmission spectrum is set. Third a predicted in vitro SPF in the measurement sample using a time until an accumulated minimal erythema dose that is obtained as a time integration of the minimal erythema doses based on the correlation obtained in the second step reaches 1 MED (Minimum Erythema Dose) is calculated.

摘要翻译： 用于评估测量样品中的紫外线辐射防护效果的方法和装置用于评估SPF（防晒因子）。 首先，测量在预定的波长范围内的预定波长间隔的测量样本中的光谱透射光谱的时间变化。 其次，设定基于光谱透射光谱的时间变化的光照射时间与最小红斑剂量之间的相关性。 第三，计算测量样品中的预测体外SPF，使用一段时间，直到基于第二步骤中获得的相关性获得的最小红斑剂量的时间积分获得的积累的最小红斑剂量达到1 MED（最小红细胞计数） 。

公开(公告)号：US20130169951A1

公开(公告)日：2013-07-04

申请号：US13823438

申请日：2011-07-13

申请人： Yoshimasa Miura ,  Masato Hatao

发明人： Yoshimasa Miura ,  Masato Hatao

IPC分类号： G01N21/59

CPC分类号： G01N21/59 ,  G01N17/004 ,  G01N21/33

摘要： An evaluation method for evaluating the ultraviolet protection effect of a measurement sample applied on a substrate includes a first step of measuring, at predetermined wavelength intervals, a change over time of a spectral transmission spectrum of the measurement sample within a predetermined wavelength range by irradiating light from a light source that includes ultraviolet light, visible light, and infrared light under a predetermined irradiation condition; a second step of establishing, based on the change over time of the spectral transmission spectrum, a correlation between a light irradiation time and an erythema effective dose per unit time, which is obtained by dividing an erythema effective dose of the measurement sample by an erythema effective dose per 1 MED; and a third step of calculating an in vitro rSPF predictive value for the measurement sample on the basis of a time until a cumulative erythema effective dose, which is obtained through time integration based on the correlation, reaches 1 MED.

摘要翻译： 用于评估施加在基板上的测量样品的紫外线保护效果的评估方法包括：第一步骤，以预定波长间隔，通过照射光来测量在预定波长范围内的测量样品的光谱透射光谱随时间的变化 从包含紫外光，可见光和红外光的光源在预定的照射条件下; 基于光谱透射光谱随时间的变化建立光照射时间和每单位时间的红斑有效剂量之间的相关性的第二步骤，其通过将测量样品的红斑有效剂量除以红斑 每1 MED有效剂量; 以及基于通过基于相关性的时间积分获得的累积红斑有效剂量之间的时间达到1 MED的时间来计算测量样品的体外rSPF预测值的第三步骤。

公开(公告)号：US08337554B2

公开(公告)日：2012-12-25

申请号：US13347203

申请日：2012-01-10

申请人： Yoshimasa Miura ,  Hiroko Mizuno ,  Masato Hatao ,  Motoki Ooguri ,  Yusuke Hara

发明人： Yoshimasa Miura ,  Hiroko Mizuno ,  Masato Hatao ,  Motoki Ooguri ,  Yusuke Hara

IPC分类号： A61F2/10 ,  B22C9/22 ,  A61B5/00

CPC分类号： G01N33/5082

摘要： A skin substitute membrane includes a surface on one side including a groove-shaped depressed portion and a planar portion, the depressed portion having a cross section having a chamfered V-letter shape, the surface having an arithmetic mean roughness Sa of more than or equal to 10 μm to less than or equal to 50 μm. The depressed portion has a width of more than or equal to 50 μm to less than or equal to 500 μm and a depth of more than or equal to 30 μm to less than or equal to 150 μm. A spectral transmittance for light of more than or equal to 290 nm to less than or equal to 400 nm in wavelength is more than or equal to 50% and less than or equal to 100%.

摘要翻译： 皮肤替代膜包括在一侧的包括凹槽状凹部和平面部的表面，所述凹部具有倒角V字形的横截面，所述表面的算术平均粗糙度Sa大于或等于 至10μm至小于或等于50μm。 凹陷部具有大于或等于50μm至小于或等于500μm的宽度和大于或等于30μm至小于或等于150μm的深度。 对于波长大于或等于290nm至小于或等于400nm的光的光谱透射率大于或等于50％且小于或等于100％。

公开(公告)号：US20100256924A1

公开(公告)日：2010-10-07

申请号：US12682286

申请日：2008-10-17

申请人： Yoshimasa Miura ,  Masato Hatao

发明人： Yoshimasa Miura ,  Masato Hatao

IPC分类号： G01N21/84 ,  G01N21/25 ,  G06F19/00

CPC分类号： G01N21/33

摘要： An evaluating method for evaluating an ultraviolet radiation protection effect in a measurement sample includes a first step of measuring a temporal change of the spectral transmission spectrum in the measurement sample within a predetermined wavelength range at predetermined wavelength intervals by irradiating with light including ultraviolet radiation from a light source under a predetermined light irradiating condition, a second step of setting a correlation between a light irradiating time and minimal erythema doses by predetermined time intervals based on the temporal change of the spectral transmission spectrum obtained in the first step, and a third step of calculating a predicted in vitro SPF in the measurement sample using a time until an accumulated minimal erythema dose that is obtained as a time integration of the minimal erythema doses based on the correlation obtained in the second step reaches 1 MED.

摘要翻译： 用于评价测定试样的紫外线防护效果的评价方法包括：第一步骤，通过用包含紫外线辐射的光进行照射，以规定的波长间隔测定预定波长范围内的测定样品中的光谱透射光谱的时间变化 光源，在第一步骤中获得的光谱透射光谱的时间变化的第二步骤，将光照射时间和最小红斑剂量之间的相关性设定预定时间间隔;第三步骤， 使用一段时间计算测量样品中预测的体外SPF，直到基于在第二步骤中获得的相关性的最小红斑剂量的时间积分获得的累积最小红斑剂量达到1 MED。

公开(公告)号：US08598535B2

公开(公告)日：2013-12-03

申请号：US13823438

申请日：2011-07-13

申请人： Yoshimasa Miura ,  Masato Hatao

发明人： Yoshimasa Miura ,  Masato Hatao

IPC分类号： G01J1/42

CPC分类号： G01N21/59 ,  G01N17/004 ,  G01N21/33

摘要： An evaluation method for evaluating the ultraviolet protection effect of a measurement sample applied on a substrate includes measuring, at predetermined wavelength intervals, a change over time of a spectral transmission spectrum of the measurement sample within a predetermined wavelength range by irradiating light from a light source that includes ultraviolet light, visible light, and infrared light under a predetermined irradiation condition; establishing, based on the change over time of the spectral transmission spectrum, a correlation between a light irradiation time and an erythema effective dose per unit time, which is obtained by dividing an erythema effective dose of the measurement sample by an erythema effective dose per 1 MED; and calculating an in vitro rSPF predictive value for the measurement sample on the basis of a time until a cumulative erythema effective dose, which is obtained through time integration based on the correlation, reaches 1 MED.

摘要翻译： 用于评估施加在基板上的测量样品的紫外线保护效果的评估方法包括：以预定波长间隔，通过照射来自光源的光来测量在预定波长范围内的测量样品的光谱透射光谱的变化 其包括在预定照射条件下的紫外光，可见光和红外光; 基于光谱透射光谱随时间的变化建立光照射时间和每单位时间红斑有效剂量之间的相关性，其通过将测量样品的红斑有效剂量除以每1个红斑有效剂量而获得 MED; 并且基于通过基于相关性的时间积分获得的累积红斑有效剂量之间的时间达到1 MED，计算测量样品的体外rSPF预测值。

公开(公告)号：US20120109300A1

公开(公告)日：2012-05-03

申请号：US13347203

申请日：2012-01-10

申请人： Yoshimasa Miura ,  Hiroko Mizuno ,  Masato Hatao ,  Motoki Ooguri ,  Yusuke Hara

发明人： Yoshimasa Miura ,  Hiroko Mizuno ,  Masato Hatao ,  Motoki Ooguri ,  Yusuke Hara

IPC分类号： A61F2/10 ,  B22C9/22 ,  A61B5/00

CPC分类号： G01N33/5082

摘要： A skin substitute membrane includes a surface on one side including a groove-shaped depressed portion and a planar portion, the depressed portion having a cross section having a chamfered V-letter shape, the surface having an arithmetic mean roughness Sa of more than or equal to 10 μm to less than or equal to 50 μm. The depressed portion has a width of more than or equal to 50 μm to less than or equal to 500 μm and a depth of more than or equal to 30 μm to less than or equal to 150 μm. A spectral transmittance for light of more than or equal to 290 nm to less than or equal to 400 nm in wavelength is more than or equal to 50% and less than or equal to 100%.

摘要翻译： 皮肤替代膜包括在一侧的包括凹槽状凹部和平面部的表面，所述凹部具有倒角V字形的横截面，所述表面的算术平均粗糙度Sa大于或等于 至10μm至小于或等于50μm。 凹陷部具有大于或等于50μm至小于或等于500μm的宽度和大于或等于30μm至小于或等于150μm的深度。 对于波长大于或等于290nm至小于或等于400nm的光的光谱透射率大于或等于50％且小于或等于100％。

公开(公告)号：US5182103A

公开(公告)日：1993-01-26

申请号：US361880

申请日：1989-06-06

申请人： Toshihiko Nakane ,  Masumi Koishi ,  Hiroshi Fukui ,  Yutaka Okunuki ,  Yoshio Yahata ,  Shigenori Kumagai ,  Hiroyuki Yokoyama ,  Eiichiro Yagi ,  Minoru Fukuda ,  Tadao Ohta ,  Fujihiro Kanda ,  Kazuhisa Ohno ,  Toshihide Ebisawa ,  Tomiyuki Nanba ,  Susumu Takada ,  Masato Hatao ,  Masaru Suetsugu ,  Toshihiro Tanaka ,  Osamu Moro

发明人： Toshihiko Nakane ,  Masumi Koishi ,  Hiroshi Fukui ,  Yutaka Okunuki ,  Yoshio Yahata ,  Shigenori Kumagai ,  Hiroyuki Yokoyama ,  Eiichiro Yagi ,  Minoru Fukuda ,  Tadao Ohta ,  Fujihiro Kanda ,  Kazuhisa Ohno ,  Toshihide Ebisawa ,  Tomiyuki Nanba ,  Susumu Takada ,  Masato Hatao ,  Masaru Suetsugu ,  Toshihiro Tanaka ,  Osamu Moro

IPC分类号： A43B17/00 ,  A61K8/11 ,  A61K8/22 ,  A61K8/26 ,  A61K31/695 ,  A61K33/06 ,  A61Q1/02 ,  A61Q1/06 ,  A61Q1/08 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/10

CPC分类号： A61Q19/00 ,  A43B17/003 ,  A61K31/695 ,  A61K33/06 ,  A61K8/11 ,  A61K8/22 ,  A61K8/26 ,  A61Q15/00 ,  A61K2800/412 ,  A61Q1/02 ,  A61Q1/06 ,  A61Q1/08 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q11/00 ,  A61Q19/10 ,  Y10S514/951

摘要： A magnesium aluminometasilicate coated composite powder which comprises magnesium aluminometasilicate, or magnesium aluminometasilicate and at least one other powder coated on a surface of a core powder and which is usable in, for example, a skin treatment agent, decodorant, and oral composition.

摘要翻译： 一种铝硅酸铝硅酸盐涂层复合粉末，其包含硅酸铝镁或硅铝酸镁，以及涂覆在芯粉表面上的至少一种其它粉末，其可用于例如皮肤处理剂，除臭剂和口腔组合物。