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公开(公告)号：US11898162B2
公开(公告)日：2024-02-13
申请号：US16818958
申请日：2020-03-13
Applicant: Wisconsin Alumni Research Foundation
Inventor： James A. Thomson , Junying Yu
IPC: C12N5/00 , C12N5/074 , C12N5/0735
CPC classification number: C12N5/0607 , C12N5/0696 , C12N5/0606 , C12N2501/60 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/605 , C12N2501/606 , C12N2501/608 , C12N2502/99 , C12N2510/00 , C12N2799/027
Abstract: The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method.
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公开(公告)号：US20200239840A1
公开(公告)日：2020-07-30
申请号：US16818958
申请日：2020-03-13
Applicant: Wisconsin Alumni Research Foundation
Inventor： James A. Thomson , Junying Yu
IPC: C12N5/074
Abstract: The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method.
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3.发明授权Enriched population of human pluripotent cells with Oct-4 and Sox2 integrated into their genome 有权富含人类的多能细胞与Oct-4和Sox2整合到其基因组中公开(公告)号：US09499786B2
公开(公告)日：2016-11-22
申请号：US13766100
申请日：2013-02-13
Applicant: Wisconsin Alumni Research Foundation
Inventor： James A. Thomson , Junying Yu
IPC: C12N15/00 , C12N5/00 , C12N5/074 , C12N5/0735
CPC classification number: C12N5/0607 , C12N5/0606 , C12N5/0696 , C12N2501/60 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/605 , C12N2501/606 , C12N2501/608 , C12N2502/99 , C12N2510/00 , C12N2799/027
Abstract: The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method.
Abstract translation: 本发明涉及通过向体细胞施用至少一种或多种效力决定因素来将体细胞重编程为多能性的方法。 本发明还涉及使用重编程方法获得的多能细胞群体。
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Patent Agency Ranking
公开(公告)号：US20190106675A1
公开(公告)日：2019-04-11
申请号：US16137899
申请日：2018-09-21
Applicant: Wisconsin Alumni Research Foundation
Inventor： James A. Thomson , Junying Yu
IPC: C12N5/074
Abstract: The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method.
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公开(公告)号：US20240271087A1
公开(公告)日：2024-08-15
申请号：US18404213
申请日：2024-01-04
Applicant: Wisconsin Alumni Research Foundation
Inventor： James A. Thomson , Junying Yu
IPC: C12N5/074 , C12N5/0735
CPC classification number: C12N5/0607 , C12N5/0696 , C12N5/0606 , C12N2501/60 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/605 , C12N2501/606 , C12N2501/608 , C12N2502/99 , C12N2510/00 , C12N2799/027
Abstract: The present invention relates to methods for reprogramming a somatic call to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method.
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公开(公告)号：US20190330654A1
公开(公告)日：2019-10-31
申请号：US16209722
申请日：2018-12-04
Applicant: Wisconsin Alumni Research Foundation
Inventor： James Thomson , Junying Yu
Abstract: Methods for reprogramming primate somatic cells to pluripotency using an episomal vector that does not encode an infectious virus are disclosed. Pluripotent cells produced in the methods are also disclosed.
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公开(公告)号：US10106772B2
公开(公告)日：2018-10-23
申请号：US13793594
申请日：2013-03-11
Applicant: Wisconsin Alumni Research Foundation
Inventor： James A. Thomson , Junying Yu
IPC: C12N15/00 , C12N5/074 , C12N5/0735
Abstract: The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method.
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公开(公告)号：US20140057355A1
公开(公告)日：2014-02-27
申请号：US13793594
申请日：2013-03-11
Applicant: Wisconsin Alumni Research Foundation
Inventor： James A. Thomson , Junying Yu
IPC: C12N5/074
CPC classification number: C12N5/0607 , C12N5/0606 , C12N5/0696 , C12N2501/60 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/605 , C12N2501/606 , C12N2501/608 , C12N2502/99 , C12N2510/00 , C12N2799/027
Abstract: The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method.
Abstract translation: 本发明涉及通过向体细胞施用至少一种或多种效力决定因素来将体细胞重编程为多能性的方法。 本发明还涉及使用重编程方法获得的多能细胞群体。
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