公开(公告)号：US20180230546A1

公开(公告)日：2018-08-16

申请号：US15880007

申请日：2018-01-25

Applicant: Wisconsin Alumni Research Foundation

Inventor： Paul Gerald Ahlquist ,  Srikumar Sengupta ,  Johan Arie den Boon ,  Bill Sugden ,  Michael Abbott Newton

IPC: C12Q1/6886 ,  C12Q1/6809 ,  C12N15/113

CPC classification number: C12Q1/6886 ,  C12N15/113 ,  C12N2310/14 ,  C12N2320/11 ,  C12N2330/10 ,  C12Q1/6809 ,  C12Q2600/106 ,  C12Q2600/158 ,  C12Q2600/178 ,  C12Q2537/143 ,  C12Q2525/207

Abstract: This invention provides methods for amplifying, detecting, measuring, and identifying miRNAs from biological samples, particularly limited amounts of a biological sample. miRNAs that are differentially expressed in tumor samples and normal tissues are useful as cancer biomarkers for cancer diagnostics.

公开(公告)号：US20160319364A1

公开(公告)日：2016-11-03

申请号：US15013189

申请日：2016-07-19

Applicant: Wisconsin Alumni Research Foundation

Inventor： Paul Gerald Ahlquist ,  Srikumar Sengupta ,  Johan Arie den Boon ,  Bill Sugden ,  Michael Abbott Newton

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12N15/113 ,  C12N2310/14 ,  C12N2320/11 ,  C12N2330/10 ,  C12Q1/6809 ,  C12Q2600/106 ,  C12Q2600/158 ,  C12Q2600/178 ,  C12Q2537/143 ,  C12Q2525/207

Abstract: This invention provides methods for amplifying, detecting, measuring, and identifying miRNAs from biological samples, particularly limited amounts of a biological sample. miRNAs that are differentially expressed in tumor samples and normal tissues are useful as cancer biomarkers for cancer diagnostics.