公开(公告)号：US09486646B2

公开(公告)日：2016-11-08

申请号：US14473858

申请日：2014-08-29

Applicant: Wisconsin Alumni Research Foundation

Inventor： Bhudatt Paliwal ,  Yue Yan

IPC: A61N5/10

CPC classification number: A61N5/1042 ,  A61N5/1067 ,  A61N2005/1095

Abstract: A system for radiation therapy includes an ionizing radiation source for producing a beam oriented along an axis aligned with a target volume for delivering ionizing radiation to the target volume along a beam path and at a dose rate, wherein the beam includes a soft spectrum and a hard spectrum. The system also includes a filter arranged within the beam path and including a central aperture that is free of beam-filtering material, wherein the central aperture is surrounded by a beam-filtering material having a thickness dimension selected and positioned in the beam path to highly attenuate the soft spectrum of the beam to reduces external scatter of the beam and allow a majority of the hard spectrum of the beam to pass through the central aperture unfiltered. The beam path is free of beam-filtering material arranged to attenuate a central portion of the beam.

Abstract translation: 一种用于放射治疗的系统包括用于产生沿着与靶体积对准的轴定向的光束的电离辐射源，用于沿光束路径和剂量率将电离辐射传送到目标体积，其中该束包括软光谱和 硬谱。 该系统还包括布置在光束路径内的滤光器，并且包括不具有光束过滤材料的中心孔，其中中心孔由具有选择并定位在光束路径中的厚度尺寸的光束过滤材料包围 衰减光束的软光谱以减少光束的外部散射，并允许光束的大部分硬谱通过未过滤的中心孔。 光束路径没有布置成衰减光束的中心部分的光束过滤材料。

公开(公告)号：US09355447B2

公开(公告)日：2016-05-31

申请号：US13971913

申请日：2013-08-21

Applicant: Wisconsin Alumni Research Foundation

Inventor： Paulina E. Galavis ,  Bhudatt Paliwal ,  James Holden ,  Robert Jeraj

IPC: G06K9/00 ,  G06T7/00 ,  G06T7/40 ,  A61N5/10

CPC classification number: G06T7/0012 ,  A61N5/103 ,  G06T7/11 ,  G06T7/155 ,  G06T7/194 ,  G06T7/41 ,  G06T2207/10104 ,  G06T2207/10108 ,  G06T2207/30016 ,  G06T2207/30096

Abstract: A system and method for analyzing medical images of a subject includes acquiring the medical images of the subject and texture images. A computer system determines, using the medical images and the texture feature images, a plurality of segmentation surfaces by iteratively adjusting a relationship between a region growing algorithm that selects a region of interest (ROI) to determine a given segmentation surface and cost function for evaluating the given segmentation surface. The computer system generates a report using the plurality of segmentation surfaces indicating at least boundaries between anatomical structures with functional differences in the medical images.

Abstract translation: 用于分析对象的医学图像的系统和方法包括获取对象的医学图像和纹理图像。 计算机系统通过迭代地调整选择感兴趣区域（ROI）的区域增长算法之间的关系来确定使用医学图像和纹理特征图像多个分割表面，以确定给定的分割表面和用于评估的成本函数 给定的分割表面。 计算机系统使用多个分割表面生成报告，所述多个分割表面至少指示解剖结构与医学图像中的功能差异之间的边界。

公开(公告)号：US20150055849A1

公开(公告)日：2015-02-26

申请号：US13971913

申请日：2013-08-21

Applicant: Wisconsin Alumni Research Foundation

Inventor： Paulina E. Galavis ,  Bhudatt Paliwal ,  James Holden ,  Robert Jeraj

IPC: G06T7/00 ,  A61N5/00

CPC classification number: G06T7/0012 ,  A61N5/103 ,  G06T7/11 ,  G06T7/155 ,  G06T7/194 ,  G06T7/41 ,  G06T2207/10104 ,  G06T2207/10108 ,  G06T2207/30016 ,  G06T2207/30096

Abstract: A system and method for analyzing medical images of a subject includes acquiring the medical images of the subject and texture images. A computer system determines, using the medical images and the texture feature images, a plurality of segmentation surfaces by iteratively adjusting a relationship between a region growing algorithm that selects a region of interest (ROI) to determine a given segmentation surface and cost function for evaluating the given segmentation surface. The computer system generates a report using the plurality of segmentation surfaces indicating at least boundaries between anatomical structures with functional differences in the medical images.

Abstract translation: 用于分析对象的医学图像的系统和方法包括获取对象的医学图像和纹理图像。 计算机系统通过迭代地调整选择感兴趣区域（ROI）的区域增长算法之间的关系来确定使用医学图像和纹理特征图像多个分割表面，以确定给定的分割表面和用于评估的成本函数 给定的分割表面。 计算机系统使用多个分割表面生成报告，所述多个分割表面至少指示解剖结构与医学图像中的功能差异之间的边界。

公开(公告)号：US20160059040A1

公开(公告)日：2016-03-03

申请号：US14473858

申请日：2014-08-29

Applicant: Wisconsin Alumni Research Foundation

Inventor： Bhudatt Paliwal ,  Yue Yan

IPC: A61N5/10

CPC classification number: A61N5/1042 ,  A61N5/1067 ,  A61N2005/1095

Abstract: A system for radiation therapy includes an ionizing radiation source for producing a beam oriented along an axis aligned with a target volume for delivering ionizing radiation to the target volume along a beam path and at a dose rate, wherein the beam includes a soft spectrum and a hard spectrum. The system also includes a filter arranged within the beam path and including a central aperture that is free of beam-filtering material, wherein the central aperture is surrounded by a beam-filtering material having a thickness dimension selected and positioned in the beam path to highly attenuate the soft spectrum of the beam to reduces external scatter of the beam and allow a majority of the hard spectrum of the beam to pass through the central aperture unfiltered. The beam path is free of beam-filtering material arranged to attenuate a central portion of the beam.

Abstract translation: 一种用于放射治疗的系统包括用于产生沿着与靶体积对准的轴定向的光束的电离辐射源，用于沿光束路径和剂量率将电离辐射传送到目标体积，其中该束包括软光谱和 硬谱。 该系统还包括布置在光束路径内的滤光器，并且包括不具有光束过滤材料的中心孔，其中中心孔由具有选择并定位在光束路径中的厚度尺寸的光束过滤材料包围 衰减光束的软光谱以减少光束的外部散射，并允许光束的大部分硬谱通过未过滤的中心孔。 光束路径没有布置成衰减光束的中心部分的光束过滤材料。