公开(公告)号：US20130144139A1

公开(公告)日：2013-06-06

申请号：US13685198

申请日：2012-11-26

申请人： Wei Zhang ,  Christoph Bardorz ,  Carsten Mueller ,  Elke Schulte

发明人： Wei Zhang ,  Christoph Bardorz ,  Carsten Mueller ,  Elke Schulte

IPC分类号： A61B5/145

CPC分类号： A61B5/14525 ,  A61B5/14557 ,  A61M1/3609 ,  A61M2205/3313 ,  G01N21/53 ,  G01N21/85

摘要： A method and device for determining the concentration of blood constituents, in particular haemoglobin, in a hose line of an extracorporeal blood circuit of an extracorporeal blood treatment apparatus, and an extracorporeal blood treatment apparatus with a device for determining the concentration of a blood constituent, are based on the correction of the influence of the blood flow rate of the blood flowing through the hose line on the determination of the concentration of the blood constituent. The device comprises a computing and evaluation unit configured such that a correction factor is ascertained for the influence of the blood flow rate on the determination of the concentration of the blood constituent. The concentration of the blood constituent is then determined based on a relationship describing the dependence of the concentration of the blood constituent on the intensity of the decoupled electromagnetic radiation, taking account of the correction factor.

摘要翻译： 一种用于确定体外血液处理装置的体外血液回路的软管管线中的血液成分浓度特别是血红蛋白的浓度的方法和装置，以及具有用于测定血液成分浓度的装置的体外血液处理装置， 基于通过软管线流动的血液的血流速度对血液成分浓度的确定的影响的校正。 该装置包括计算和评估单元，其被配置为使得针对血液流量对血液成分浓度的确定的影响确定校正因子。 然后考虑校正因子，基于描述血液成分的浓度对解耦电磁辐射的强度的依赖性的关系来确定血液成分的浓度。

公开(公告)号：US20130033697A1

公开(公告)日：2013-02-07

申请号：US13554145

申请日：2012-07-20

申请人： Wei Zhang ,  Elke Schulte ,  Martin Kaiser ,  Carsten Mueller ,  Tom Klein ,  Stefan Zerle ,  Christoph Bardorz ,  Stefan Stuehler

发明人： Wei Zhang ,  Elke Schulte ,  Martin Kaiser ,  Carsten Mueller ,  Tom Klein ,  Stefan Zerle ,  Christoph Bardorz ,  Stefan Stuehler

IPC分类号： G01N33/49 ,  G01N27/00

CPC分类号： G01N33/49 ,  A61B5/14557 ,  A61M1/367 ,  A61M2205/14 ,  A61M2205/3306 ,  A61M2230/20 ,  G01N21/05 ,  G01N21/31 ,  G01N2021/0378 ,  G01N2021/3144

摘要： A device for determining the concentration of a constituent of blood in a hose line, in particular in the hose line of an extracorporeal blood circuit of an extracorporeal blood treatment apparatus, includes a clamping unit having an actuation mechanism configured to apply a clamping force such that first and second receiving elements are moved towards one another from a first position releasing the hose line into a second position clamping the hose line, in which the drive of the actuation mechanism takes place with an electric motor, and a monitoring unit configured to detect a hose line inserted into the receiving elements. A method for detecting a hose line in a clamping unit of a device for determining the concentration of a blood constituent in the hose line is also described. Automation of the measurement of the blood parameters is thus possible.

摘要翻译： 一种用于确定软管管线中的血液成分浓度的装置，特别是在体外血液处理设备的体外血液回路的软管管线中的装置，包括具有致动机构的夹紧单元，该致动机构构造成施加夹紧力，使得 第一和第二接收元件从第一位置朝向彼此移动，从而将软管线释放到夹紧软管线的第二位置，在该第二位置中，使用电动机进行致动机构的驱动;以及监视单元， 软管线插入接收元件。 还描述了用于检测用于确定软管管线中的血液成分浓度的装置的夹持单元中的软管线的方法。 因此血液参数测量的自动化是可能的。

公开(公告)号：US08858486B2

公开(公告)日：2014-10-14

申请号：US12744281

申请日：2008-11-22

申请人： Wei Zhang ,  Elke Schulte ,  Christoph Bardorz

发明人： Wei Zhang ,  Elke Schulte ,  Christoph Bardorz

IPC分类号： A61M37/00 ,  A61M1/36 ,  A61M1/16

CPC分类号： A61M1/16 ,  A61M1/1617 ,  A61M1/3658 ,  A61M2205/13

摘要： A method for determining the recirculation in a fistula and/or the cardiopulmonary recirculation part during an extracorporeal blood treatment is disclosed, where the blood to be treated flows in an extracorporeal blood circuit through a blood chamber of a dialyzer split by a semi-permeable membrane into the blood chamber and a liquid chamber, and dialysis liquid flows in a dialysis liquid path through the dialysis liquid chamber of the dialyzer. A device for determining the recirculation in a fistula and/or the cardiopulmonary recirculation part, and a blood treatment device including such a device are also disclosed. The method and device are based on the fact that the sum of the fistula recirculation and the cardiopulmonary recirculation part, i.e. the total recirculation, is determined for two blood flow rates which differ from each other. The fistula recirculation and/or the cardiopulmonary recirculation part are then determined from the recirculation for the two blood flow rates.

摘要翻译： 公开了一种用于在体外血液处理期间确定瘘管和/或心肺再循环部分中的再循环的方法，其中待治疗的血液通过半透膜分离的透析器的血室在体外血液回路中流动 进入血液室和液体室，并且透析液体在透析液体路径中流过透析器的透析液体室。 还公开了一种用于确定瘘管和/或心肺再循环部分中的再循环的装置，以及包括这种装置的血液处理装置。 该方法和装置基于以下事实：对于彼此不同的两个血液流速，确定瘘再循环和心肺再循环部分的总和，即总再循环。 然后从两次血流速率的再循环中确定瘘再循环和/或心肺再循环部分。

公开(公告)号：US08792089B2

公开(公告)日：2014-07-29

申请号：US13554145

申请日：2012-07-20

申请人： Wei Zhang ,  Elke Schulte ,  Martin Kaiser ,  Carsten Mueller ,  Tom Klein ,  Stefan Zerle ,  Christoph Bardorz ,  Stefan Stuehler

发明人： Wei Zhang ,  Elke Schulte ,  Martin Kaiser ,  Carsten Mueller ,  Tom Klein ,  Stefan Zerle ,  Christoph Bardorz ,  Stefan Stuehler

IPC分类号： G01N33/48

CPC分类号： G01N33/49 ,  A61B5/14557 ,  A61M1/367 ,  A61M2205/14 ,  A61M2205/3306 ,  A61M2230/20 ,  G01N21/05 ,  G01N21/31 ,  G01N2021/0378 ,  G01N2021/3144

摘要： A device for determining the concentration of a constituent of blood in a hose line, in particular in the hose line of an extracorporeal blood circuit of an extracorporeal blood treatment apparatus, includes a clamping unit having an actuation mechanism configured to apply a clamping force such that first and second receiving elements are moved towards one another from a first position releasing the hose line into a second position clamping the hose line, in which the drive of the actuation mechanism takes place with an electric motor, and a monitoring unit configured to detect a hose line inserted into the receiving elements. A method for detecting a hose line in a clamping unit of a device for determining the concentration of a blood constituent in the hose line is also described. Automation of the measurement of the blood parameters is thus possible.

摘要翻译： 一种用于确定软管管线中的血液成分浓度的装置，特别是在体外血液处理设备的体外血液回路的软管管线中的装置，包括具有致动机构的夹紧单元，该致动机构构造成施加夹紧力，使得 第一和第二接收元件从第一位置朝向彼此移动，从而将软管线释放到夹紧软管线的第二位置，其中致动机构的驱动通过电动机进行，以及监视单元，其被配置为检测 软管线插入接收元件。 还描述了用于检测用于确定软管管线中的血液成分浓度的装置的夹持单元中的软管线的方法。 因此血液参数测量的自动化是可能的。

公开(公告)号：US20110004141A1

公开(公告)日：2011-01-06

申请号：US12744281

申请日：2007-11-22

申请人： Wei Zhang ,  Elke Schulte ,  Christoph Bardorz

发明人： Wei Zhang ,  Elke Schulte ,  Christoph Bardorz

IPC分类号： A61M1/16 ,  A61M1/36

CPC分类号： A61M1/16 ,  A61M1/1617 ,  A61M1/3658 ,  A61M2205/13

摘要： A method for determining the recirculation in a fistula and/or the cardiopulmonary recirculation part during an extracorporeal blood treatment is disclosed, where the blood to be treated flows in an extracorporeal blood circuit through a blood chamber of a dialyzer split by a semi-permeable membrane into the blood chamber and a liquid chamber, and dialysis liquid flows in a dialysis liquid path through the dialysis liquid chamber of the dialyzer. A device for determining the recirculation in a fistula and/or the cardio-pulmonary recirculation part, and a blood treatment device including such a device are also disclosed. The method and device are based on the fact that the sum of the fistula recirculation and the cardiopulmonary recirculation part, i.e. the total recirculation, is determined for two blood flow rates which differ from each other. The fistula recirculation and/or the cardiopulmonary recirculation part are then determined from the recirculation for the two blood flow rates.

摘要翻译： 公开了一种用于在体外血液处理期间确定瘘管和/或心肺再循环部分中的再循环的方法，其中待治疗的血液通过半透膜分离的透析器的血室在体外血液回路中流动 进入血液室和液体室，并且透析液体在透析液体路径中流过透析器的透析液体室。 还公开了一种用于确定瘘管和/或心肺再循环部分中的再循环的装置，以及包括这种装置的血液处理装置。 该方法和装置基于以下事实：对于彼此不同的两个血液流速，确定瘘再循环和心肺再循环部分的总和，即总再循环。 然后从两次血流速率的再循环中确定瘘再循环和/或心肺再循环部分。

公开(公告)号：US09878081B2

公开(公告)日：2018-01-30

申请号：US12596613

申请日：2008-04-17

申请人： Claus Leiendecker ,  Carsten Müller ,  Elke Schulte ,  Wei Zhang

发明人： Claus Leiendecker ,  Carsten Müller ,  Elke Schulte ,  Wei Zhang

IPC分类号： G06Q50/22 ,  A61M1/14 ,  G06Q50/24 ,  A61B90/90 ,  A61B90/98 ,  A61B5/021 ,  A61B5/024 ,  A61B17/00 ,  A61B5/00

CPC分类号： A61M1/14 ,  A61B5/002 ,  A61B5/021 ,  A61B5/024 ,  A61B90/90 ,  A61B90/98 ,  A61B2017/00119 ,  A61B2017/00221 ,  A61B2017/00482 ,  A61B2562/08 ,  A61M2205/3569 ,  A61M2205/3576 ,  A61M2205/6018 ,  A61M2205/6054 ,  A61M2205/8237 ,  A61M2205/84 ,  G06F19/00 ,  G06Q50/24 ,  G16H10/60

摘要： An assembly includes at least two medical treatment units, each of which can be allocated to a patient and at least two peripheral devices, each of which can be allocated to a patient. The peripheral devices and the treatment units have means for allocating a peripheral device to a treatment unit and means for verifying the allocation of a peripheral device to a patient. To allocate a peripheral device to a treatment unit, the peripheral device is placed by operators in a receiving unit belonging to the treatment unit. Said receiving unit is preferably designed as a charging station for the battery of the peripheral device. In the event of a successful allocation of peripheral device and patient, confirmed by the receipt of physiological data of the patient, the operators verify the correct allocation of a peripheral device to the patient and must confirm the correct allocation by confirmation means. The peripheral device is only released if the operator has confirmed the correct allocation, preferably within a predefined time period.

公开(公告)号：US20090078622A1

公开(公告)日：2009-03-26

申请号：US11922433

申请日：2006-06-09

申请人： Wei Zhang ,  Elke Schulte

发明人： Wei Zhang ,  Elke Schulte

IPC分类号： A61M1/36 ,  A61M1/16 ,  B01D61/30

CPC分类号： A61M1/3639 ,  A61B5/0002 ,  A61B5/021 ,  A61B5/024 ,  A61M1/16 ,  A61M2205/3569 ,  A61M2205/3576 ,  A61M2205/3592 ,  A61M2230/06 ,  A61M2230/30

摘要： The invention relates to a dialyser with a measuring unit assigned thereto that transmits data to said dialyser via a wireless link, the measuring unit being able to determine and transmit to the dialyser at least one measurable variable which can also be determined by another measuring device that is connected physically to the dialyser, a comparison of the at least one measurable variable as determined by the measuring unit and by the measuring device indicating whether the measuring unit is indeed the one assigned to the dialyser in question and/or whether the measuring unit is working properly.

摘要翻译： 本发明涉及一种具有分配给其的测量单元的透析器，其经由无线链路将数据发送到所述透析器，所述测量单元能够确定并向透析器发送至少一个可测量的变量，其也可由另一测量设备确定 物理地与透析器连接，由测量单元确定的至少一个可测量变量与测量设备的比较，指示测量单元是否确实是分配给所述透析器的测量单元和/或测量单元是否为 好好工作。

公开(公告)号：US20100114639A1

公开(公告)日：2010-05-06

申请号：US12596613

申请日：2008-04-17

申请人： Claus Leiendecker ,  Carsten Müller ,  Elke Schulte ,  Wei Zhang

发明人： Claus Leiendecker ,  Carsten Müller ,  Elke Schulte ,  Wei Zhang

IPC分类号： G06Q10/00 ,  A61M1/14 ,  G06F15/16

CPC分类号： A61M1/14 ,  A61B5/002 ,  A61B5/021 ,  A61B5/024 ,  A61B90/90 ,  A61B90/98 ,  A61B2017/00119 ,  A61B2017/00221 ,  A61B2017/00482 ,  A61B2562/08 ,  A61M2205/3569 ,  A61M2205/3576 ,  A61M2205/6018 ,  A61M2205/6054 ,  A61M2205/8237 ,  A61M2205/84 ,  G06F19/00 ,  G06Q50/24 ,  G16H10/60

摘要： An assembly includes at least two medical treatment units, each of which can be allocated to a patient and at least two peripheral devices, each of which can be allocated to a patient. The peripheral devices and the treatment units have means for allocating a peripheral device to a treatment unit and means for verifying the allocation of a peripheral device to a patient. To allocate a peripheral device to a treatment unit, the peripheral device is placed by operators in a receiving unit belonging to the treatment unit. Said receiving unit is preferably designed as a charging station for the battery of the peripheral device. In the event of a successful allocation of peripheral device and patient, confirmed by the receipt of physiological data of the patient, the operators verify the correct allocation of a peripheral device to the patient and must confirm the correct allocation by confirmation means. The peripheral device is only released if the operator has confirmed the correct allocation, preferably within a predefined time period.

摘要翻译： 组件包括至少两个医疗单元，每个医疗单元可以分配给患者和至少两个外围设备，每个外围设备可以分配给患者。 外围设备和治疗单元具有用于将外围设备分配给治疗单元的装置和用于验证外围设备对患者的分配的装置。 为了将外围设备分配给治疗单元，外围设备由操作员放置在属于治疗单元的接收单元中。 所述接收单元优选地被设计为用于外围设备的电池的充电站。 在外部设备和患者的成功分配的情况下，通过接收患者的生理数据确认，操作者验证外部设备对患者的正确分配，并且必须通过确认手段确认正确的分配。 如果操作者已经确定了正确的分配，则优选地在预定的时间段内，外围设备才被释放。

公开(公告)号：US20090223880A2

公开(公告)日：2009-09-10

申请号：US11922433

申请日：2007-12-18

申请人： Wei Zhang ,  Elke Schulte

发明人： Wei Zhang ,  Elke Schulte

IPC分类号： A61M1/36 ,  A61M1/16 ,  B01D61/30

CPC分类号： A61M1/3639 ,  A61B5/0002 ,  A61B5/021 ,  A61B5/024 ,  A61M1/16 ,  A61M2205/3569 ,  A61M2205/3576 ,  A61M2205/3592 ,  A61M2230/06 ,  A61M2230/30

摘要： The invention relates to a dialyser with a measuring unit assigned thereto that transmits data to the dialyser via a wireless link, the measuring unit being able to determine and transmit to the dialyser at least one measurable variable which can also be determined by another measuring device that is connected physically to the dialyser, a comparison of the at least one measurable variable as determined by the measuring unit and by the measuring device indicating whether the measuring unit is indeed the one assigned to the dialyser in question and/or whether the measuring unit is working properly.

摘要翻译： 本发明涉及一种具有分配给其的测量单元的透析器，其经由无线链路将数据发送到透析器，所述测量单元能够确定并向透析器传送至少一个可测量的变量，其也可由另一测量设备确定 物理地与透析器连接，由测量单元确定的至少一个可测量变量与测量设备的比较，指示测量单元是否确实是分配给所述透析器的测量单元和/或测量单元是否为 好好工作。

公开(公告)号：US20100298751A1

公开(公告)日：2010-11-25

申请号：US12742415

申请日：2008-11-11

申请人： Elke Schulte ,  Carsten Müller

发明人： Elke Schulte ,  Carsten Müller

IPC分类号： A61M1/14

CPC分类号： A61M1/342 ,  A61B5/14532 ,  A61M1/1609 ,  A61M1/34 ,  A61M1/3434 ,  A61M1/3437 ,  A61M1/3458 ,  A61M5/1723 ,  A61M2230/201 ,  B01D61/32 ,  C12Q1/54

摘要： The present invention relates to a method for detecting at least one characteristic relating to a patient's glucose metabolism, having steps to be performed during an extracorporeal treatment of the patient's blood, particularly during a dialysis treatment, of the extracorporeal addition of glucose and/or insulin and extracorporeal measurement of a glucose concentration and/or an insulin concentration. The invention further proposes a corresponding device. In addition, the invention proposes a method for determining the composition of the dialysate for the extracorporeal treatment of a patient's blood having the steps of determining a glucose level in the patient's blood during the dialysis session and adapting the amount of glucose added to the dialysate or blood based on the glucose level determined. To this end, the invention proposes a corresponding device. The invention further proposes a blood treatment device.

摘要翻译： 本发明涉及一种用于检测与患者的葡萄糖代谢相关的至少一个特征的方法，其具有在体外加工葡萄糖和/或胰岛素的体外治疗患者血液，特别是在透析治疗期间进行的步骤 和体外测量葡萄糖浓度和/或胰岛素浓度。 本发明还提出了一种相应的装置。 此外，本发明提出了一种用于确定用于患者血液的体外治疗的透析液的组成的方法，该方法具有以下步骤：在透析期间确定患者血液中的葡萄糖水平并调整加入到透析液中的葡萄糖量， 血糖基于葡萄糖水平测定。 为此，本发明提出了一种相应的装置。 本发明还提出一种血液处理装置。