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    AQUEOUS IRON CARBOHYDRATE COMPLEXES, THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM
    2.
    发明申请
    AQUEOUS IRON CARBOHYDRATE COMPLEXES, THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM 审中-公开
    水溶性碳水化合物复合物，其生产和药物含有它们

    公开(公告)号：US20130203698A1

    公开(公告)日：2013-08-08

    申请号：US13835400

    申请日：2013-03-15

    申请人： Vifor (International) AG.

    发明人： Peter Geisser ,  Erik Philipp ,  Walter Richle

    IPC分类号： C08B37/00

    摘要： Water soluble Iron carbohydrate complex obtainable from an aqueous solution of iron(III) salt and an aqueous solution of the oxidation product of one or more maltrodextrins using an aqueous hypochlorite solution at a pH-value within the alkaline range, where, when one maltodextrin is applied, its dextrose equivalent lies between 5 and 20, and when a mixture of several maltodextrins is applied, the dextrose equivalent of the mixture lies between 5 and 20 and the dextrose equivalent of each individual maltodextrin contained in the mixture lies between 2 and 40, process for its production and medicament for the treatment and prophylaxis of iron deficiency conditions.

    摘要翻译： 水溶性铁碳水化合物复合物可以使用碱性范围内的pH值，使用碱性范围内的pH值从铁（III）盐水溶液和一种或多种麦芽糖糊精的氧化产物的水溶液中获得，其中当一个麦芽糖糊精为 其葡萄糖当量为5至20，当应用几种麦芽糖糊精的混合物时，混合物的葡萄糖当量为5至20，并且混合物中所含的每个单独的麦芽糖糊精的葡萄糖当量为2至40， 其制备方法和用于治疗和预防缺铁病症的药物。

    Preparation Comprising Iron(III) Complex Compounds And Redox-Active Substance(s)
    6.
    发明申请
    Preparation Comprising Iron(III) Complex Compounds And Redox-Active Substance(s) 审中-公开
    包含铁（III）络合物和氧化还原活性物质的制备

    公开(公告)号：US20130157974A1

    公开(公告)日：2013-06-20

    申请号：US13735228

    申请日：2013-01-07

    申请人： VIFOR (INTERNATIONAL) AG

    发明人： Priska Ziegler ,  Peter Geisser

    IPC分类号： A61K31/715 ,  A61K31/375 ,  A61K45/06

    CPC分类号： A61K31/715 ,  A61K31/295 ,  A61K31/375 ,  A61K33/26 ,  A61K45/06 ,  A61K2300/00

    摘要： A preparation is disclosed that comprises one or more iron(III) complex compounds which have a redox potential at pH 7 of from −324 mV to −750 mV relative to a normal hydrogen electrode (NHE), and one or more redox-active substances, wherein the carbohydrates are selected from the group consisting of dextrans and hydrogenated dextrans, dextrins, oxidised or hydrogenated dextrins, as well as pullulan, oligomers thereof and/or hydrogenated pullulans, and wherein the redox-active substance(s) is/are selected from the group consisting of ascorbic acid; vitamin E; cysteine; physiologically acceptable phenols/polyphenols selected from the group consisting of quercetin, rutin, flavones, flavonoids, hydroquinones; and glutathione, and in particular is ascorbic acid.

    摘要翻译： 公开了一种制剂，其包含一种或多种相对于正常氢电极（NHE）在pH7为-324mV至-750mV的氧化还原电位的一种或多种铁（III）络合物化合物，以及一种或多种氧化还原活性物质 其中所述碳水化合物选自葡聚糖和氢化葡聚糖，糊精，氧化或氢化糊精，以及支链淀粉，其低聚物和/或氢化支链淀粉，并且其中所述氧化还原活性物质被选择 由抗坏血酸组成; 维生素E; 半胱氨酸 选自槲皮素，芦丁，黄酮，类黄酮，氢醌的生理学上可接受的酚/多酚; 和谷胱甘肽，特别是抗坏血酸。