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公开(公告)号：US20190225628A1
公开(公告)日：2019-07-25
申请号：US16238363
申请日：2019-01-02
Applicant: VenatoRx Pharmaceuticals, Inc.
Inventor： Christopher J. BURNS , Denis DAIGLE , Bin LIU , Daniel McGARRY , Daniel C. PEVEAR , Robert E. Lee TROUT
Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
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公开(公告)号：US20170342093A1
公开(公告)日：2017-11-30
申请号：US15675262
申请日：2017-08-11
Applicant: VenatoRx Pharmaceuticals, Inc.
Inventor： Christopher J. BURNS , Denis DAIGLE , Bin LIU , Daniel McGARRY , Daniel C. PEVEAR , Robert E. Lee TROUT , Randy W. JACKSON
IPC: C07F5/02 , A61K31/546 , A61K31/407 , A61K31/496 , A61K45/06 , A61K31/69
CPC classification number: C07F5/025 , A61K31/407 , A61K31/496 , A61K31/546 , A61K31/69 , A61K45/06 , Y02A50/47 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , Y02A50/483
Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
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公开(公告)号：US20170145037A1
公开(公告)日：2017-05-25
申请号：US15366769
申请日：2016-12-01
Applicant: VenatoRx Pharmaceuticals, Inc.
Inventor： Christopher J. BURNS , Denis DAIGLE , Jodie HAMRICK , Bin LIU , Randy W. JACKSON , Daniel McGARRY , Daniel C. PEVEAR , Robert E. Lee TROUT
CPC classification number: C07F5/025 , A61K31/427 , A61K31/43 , A61K31/69 , A61K45/06 , Y02A50/473 , Y02A50/475 , Y02A50/481 , A61K2300/00
Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases and methods thereof. In some embodiments, the compounds described herein are biologically hydrolyzed to a beta-lactamase inhibitor. In certain embodiments, the compounds described herein are useful for the treatment of bacterial infections.
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公开(公告)号：US20140194386A1
公开(公告)日：2014-07-10
申请号：US14152916
申请日：2014-01-10
Applicant: VenatoRx Pharmaceuticals, Inc.
Inventor： Christopher J. BURNS , Denis DAIGLE , Bin LIU , Daniel McGARRY , Daniel C. PEVEAR , Robert E. Lee TROUT , Randy W. JACKSON
IPC: C07F5/02
CPC classification number: C07F5/025 , A61K31/407 , A61K31/496 , A61K31/546 , A61K31/69 , A61K45/06 , Y02A50/47 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , Y02A50/483
Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
Abstract translation: 本文描述了调节β-内酰胺酶活性的化合物和组合物。 在一些实施方案中，本文所述的化合物抑制β-内酰胺酶。 在某些实施方案中，本文所述的化合物可用于治疗细菌感染。
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公开(公告)号：US20210163506A1
公开(公告)日：2021-06-03
申请号：US17115514
申请日：2020-12-08
Applicant: VENATORX PHARMACEUTICALS, INC.
Inventor： Franz AMANN , Matthew M. BIO , Jonas BÜRGLER , Yuanqing FANG , David FORD , Daniel McGARRY
IPC: C07F5/02
Abstract: Described herein are boron-containing compounds, compositions, and methods for their preparation.
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Patent Agency Ranking
公开(公告)号：US20160264598A1
公开(公告)日：2016-09-15
申请号：US15162395
申请日：2016-05-23
Applicant: VenatoRx Pharmaceuticals, Inc.
Inventor： Christopher J. BURNS , Denis DAIGLE , Bin LIU , Randy W. JACKSON , Jodie HAMRICK , Daniel McGARRY , Daniel C. PEVEAR , Robert E. Lee TROUT
CPC classification number: C07F5/025 , A61K31/198 , A61K31/69 , A61K45/06 , A61K2300/00
Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
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公开(公告)号：US20150361108A1
公开(公告)日：2015-12-17
申请号：US14737156
申请日：2015-06-11
Applicant: VenatoRX Pharmaceuticals, Inc.
Inventor： Christopher J. BURNS , Denis DAIGLE , Jodie HAMRICK , Bin LIU , Randy W. JACKSON , Daniel McGARRY , Daniel C. PEVEAR , Robert E. Lee TROUT
CPC classification number: C07F5/025 , A61K31/427 , A61K31/43 , A61K31/69 , A61K45/06 , Y02A50/473 , Y02A50/475 , Y02A50/481 , A61K2300/00
Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases and methods thereof. In some embodiments, the compounds described herein are biologically hydrolyzed to a beta-lactamase inhibitor. In certain embodiments, the compounds described herein are useful for the treatment of bacterial infections.
Abstract translation: 本文描述了调节β-内酰胺酶活性的化合物和组合物及其方法。 在一些实施方案中，本文所述的化合物生物水解成β-内酰胺酶抑制剂。 在某些实施方案中，本文所述的化合物可用于治疗细菌感染。
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公开(公告)号：US20200317698A1
公开(公告)日：2020-10-08
申请号：US16864634
申请日：2020-05-01
Applicant: VenatoRx Pharmaceuticals, Inc.
Inventor： Christopher J. BURNS , Denis DAIGLE , Bin LIU , Daniel McGARRY , Daniel C. PEVEAR , Robert E. Lee TROUT , Randy W. JACKSON
IPC: C07F5/02 , A61K31/69 , A61K45/06 , A61K31/407 , A61K31/496 , A61K31/546
Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
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公开(公告)号：US20170226135A1
公开(公告)日：2017-08-10
申请号：US15435097
申请日：2017-02-16
Applicant: VenatoRx Pharmaceuticals, Inc.
Inventor： Christopher J. BURNS , Denis DAIGLE , Bin LIU , Randy W. JACKSON , Jodie HAMRICK , Daniel McGARRY , Daniel C. PEVEAR , Robert E. Lee TROUT
CPC classification number: C07F5/025 , A61K31/198 , A61K31/69 , A61K45/06 , A61K2300/00
Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
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公开(公告)号：US20160016978A1
公开(公告)日：2016-01-21
申请号：US14759853
申请日：2014-01-10
Applicant: VENATORX PHARMACEUTICALS, INC.
Inventor： Christopher J. BURNS , Denis DAIGLE , Bin LIU , Daniel McGARRY , Daniel C. PEVEAR , Robert E. Lee TROUT , Randy W. JACKSON
IPC: C07F5/02 , A61K31/496 , A61K31/407 , A61K31/69 , A61K31/546
CPC classification number: C07F5/025 , A61K31/407 , A61K31/496 , A61K31/546 , A61K31/69 , A61K45/06 , Y02A50/47 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , Y02A50/483
Abstract: Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
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