公开(公告)号：US20210307611A1

公开(公告)日：2021-10-07

申请号：US16838875

申请日：2020-04-02

申请人： University of Rochester

发明人： Jose Fernando ZVIETCOVICH ZEGARRA ,  Jannick P. Rolland ,  Cristina Canavesi ,  Kevin J. Parker

IPC分类号： A61B5/00 ,  G02B21/00 ,  G02B6/42 ,  G02B21/36 ,  G06T7/00

摘要： a) A Gabor domain optical coherence microscopy (GD-OCM) system providing high resolution of structural and motion imaging of objects such as tissues is combined with the use of reverberant shear wave fields (RevSW) or longitudinal shear waves (LSW) and two novel mechanical excitation sources: a coaxial coverslip excitation (CCE) and a multiple pronged excitation (MPE) sources providing structured and controlled mechanical excitation in tissues and leading to accurate derivation of elastographic properties. Alternatively, general optical computed tomography (OCT) is combined with RevSW or LWC in the object to derive elastographic properties. The embodiments include (a) GD-OCM with RevSW; (b) GD-OCM with LSW; (c) General OCT with RevSW; and General OCT with LSW.