专利检索 ap:("University of Rhode Island Board of Trustees" OR "Yale University") AND inv:"Kassie Picard" 第 1 页

1.

发明公开
POLY(ETHYLENE BRASSYLATE-CO-DIOXANONE) COPOLYMERS, METHOD OF SYNTHESIS AND BIOMEDICAL DEVICES MADE THEREFROM 审中-公开

公开(公告)号：US20240343859A1

公开(公告)日：2024-10-17

申请号：US18628340

申请日：2024-04-05

申请人： University of Rhode Island Board of Trustees , Yale University

发明人： Matthew Kiesewetter , Kassie Picard , Jinal Pothupitiya , W. Mark Saltzman

IPC分类号： C08G63/08 , A61L27/18 , A61L27/54 , A61L27/58

CPC分类号： C08G63/08 , A61L27/18 , A61L27/54 , A61L27/58

摘要： Embodiments of the present invention comprises one or more of an article composed of a copolymer, a copolymer made from a process, and a process for the preparation of a copolymer composition by metal free enzyme ring-opening polymerization of a monomer composition comprising i) an ethylene brassylate monomer; ii) a 1-4 dioxan-2-one (DO); iii) lipase B from Candida antarctica (Novozyme® 435) and at an elevated temperature, processing the monomer reactants i) and ii) to a copolymer via ring-opening polymerization under solvent-free conditions and a nitrogen atmosphere in the absence of a metal and the presence of the lipase to produce a random EB-co-DO copolymer.