公开(公告)号：US20240316128A1

公开(公告)日：2024-09-26

申请号：US18427867

申请日：2024-01-31

申请人： Unique Biotech Limited

发明人： Manoj Pandurang Dandekar ,  Shubham Gopal Ghuge ,  Ziaur Rahman ,  Ratna Sudha Madempudi

IPC分类号： A61K35/747 ,  A61K31/198 ,  A61K35/742 ,  A61K35/745 ,  A61P25/00

CPC分类号： A61K35/747 ,  A61K31/198 ,  A61K35/742 ,  A61K35/745 ,  A61P25/00

摘要： The current invention discloses the use of a multi-strain probiotic formulation comprising one or more novel Lactobacilli, Bifidobacterium and Bacillus strains for the alleviation, prevention and treatment of obsessive-compulsive disorder and/or obsessive-compulsive disorder like symptoms. The multi-strain probiotic formulation disclosed herein for use as treatment for obsessive-compulsive disorder symptoms comprises Bacillus coagulans Unique IS-2, Lactobacillus plantarum UBLP-40, Lactobacillus rhamnosus UBLR-58, Bifidobacterium lactis UBBLa-70, Bifidobacterium breve UBBr-01, and Bifidobacterium infantis UBBI-01.

公开(公告)号：US20240261344A1

公开(公告)日：2024-08-08

申请号：US18609012

申请日：2024-03-19

申请人： Unique Biotech Limited

发明人： Ratna Sudha Madempudi ,  Manoj P. Dandekar ,  Manisurya Kumar Palepu ,  Srilakshmi Satya Satti

IPC分类号： A61K35/742 ,  A61P25/22 ,  A61P25/24

CPC分类号： A61K35/742 ,  A61P25/22 ,  A61P25/24

摘要： The current invention more specifically relates to methods of amelioration of symptoms of anxiety and depression by using a probiotic formulation comprising Bacillus coagulans. The probiotic formulation used for the amelioration of depression and anxiety symptoms may comprise a novel strain of Bacillus coagulans (Unique IS-2) (MTCC 5260, ATCC PTA-11748), which is used for treating, preventing or ameliorating at least one symptom of anxiety, stress, depression or a depressive disorder.
The current invention discloses a method for treating, preventing or ameliorating at least one symptom of depression or a depressive disorder, the method comprising the step of administering to a subject an effective dosage regimen of a probiotic formulation comprising Bacillus coagulans.

公开(公告)号：US20240335487A1

公开(公告)日：2024-10-10

申请号：US18609015

申请日：2024-03-19

申请人： Unique Biotech Limited

发明人： Ratna Sudha Madempudi ,  Manoj Pandurang Dandekar ,  Manisurya Kumar Palepu ,  Srilakshmi Satya Satti

IPC分类号： A61K35/747 ,  A61K31/198 ,  A61K35/742 ,  A61K35/745 ,  A61P25/24

CPC分类号： A61K35/747 ,  A61K31/198 ,  A61K35/742 ,  A61K35/745 ,  A61P25/24

摘要： Multi-strain probiotic formulation for ameliorating and preventing symptoms of treatment resistant depression
The current invention more specifically relates to methods and compositions comprising a multi-strain probiotic formulation that can be used for alleviating symptoms of treatment-resistant depression in humans.
The multi-strain probiotic formulation disclosed herein for use as treatment for treatment-resistant depression symptoms comprises Bacillus coagulans, Lactobacillus plantarum, Lactobacillus rhamnosus, Bifidobacterium lactis, Bifidobacterium breve, and Bifidobacterium infantis. More specifically, the multi-strain probiotic formulation comprises Bacillus coagulans Unique IS-2, Lactobacillus plantarum UBLP-40, Lactobacillus rhamnosus UBLR-58, Bifidobacterium lactis UBBLa-70, Bifidobacterium breve UBBr-01, and Bifidobacterium infantis UBBI-01.

公开(公告)号：US20240307461A1

公开(公告)日：2024-09-19

申请号：US18430704

申请日：2024-02-02

申请人： Unique Biotech Limited

发明人： Ratna Sudha Madempudi ,  Jayanthi Neelamraju

IPC分类号： A61K35/742 ,  A61P1/00

CPC分类号： A61K35/742 ,  A61P1/00

摘要： The current invention discloses the method of treating, preventing and/or ameliorating Inflammatory Bowel Disease in patients by administering a probiotic composition comprising Bacillus clausii. The current invention discloses a method for, prevention and/or treatment, and amelioration of symptoms of Inflammatory Bowel Disease by use of Bacillus clausii, which modulates the microbiome in the gastro-intestinal tract and decreases inflammation in the patients.