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公开(公告)号:US20190216945A1
公开(公告)日:2019-07-18
申请号:US16334301
申请日:2017-10-13
发明人: Jiyuan Yang , Jindrich Kopecek , Libin Zhang , Yixin Fang
CPC分类号: A61K47/6883 , A61K31/337 , A61K31/351 , A61K38/07 , A61K39/395 , A61K47/58 , A61K2039/505 , A61P35/00 , C07K16/2803 , C07K16/2887 , C07K2317/92 , C07K2319/035
摘要: Disclosed herein, are antibody-polymer-drug conjugates. The conjugate comprises a targeting moiety, one or more polymers, and one or more therapeutic agents. Also described herein, are compositions comprising the conjugates, methods of their preparation, and methods of treating various disorders with the conjugates or their compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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公开(公告)号:US11801307B2
公开(公告)日:2023-10-31
申请号:US16334301
申请日:2017-10-13
发明人: Jiyuan Yang , Jindrich Kopecek , Libin Zhang , Yixin Fang
IPC分类号: A61K47/68 , A61P35/00 , C07K16/28 , A61K39/395 , A61K38/07 , A61K47/58 , A61K39/00 , A61K31/337 , A61K31/351
CPC分类号: A61K47/6883 , A61K38/07 , A61K39/395 , A61K47/58 , A61P35/00 , C07K16/2803 , C07K16/2887 , A61K31/337 , A61K31/351 , A61K2039/505 , C07K2317/92 , C07K2319/035
摘要: Disclosed herein, are antibody-polymer-drug conjugates. The conjugate comprises a targeting moiety, one or more polymers, and one or more therapeutic agents. Also described herein, are compositions comprising the conjugates, methods of their preparation, and methods of treating various disorders with the conjugates or their compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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