公开(公告)号：US11981892B2

公开(公告)日：2024-05-14

申请号：US16384612

申请日：2019-04-15

Applicant: UNIVERSITY OF MASSACHUSETTS

Inventor： Craig Cameron Mello ,  Krishna Sumanth Ghanta ,  Gregoriy Dokshin ,  Aamir Mir ,  Hassan Gneid ,  Jonathan Kenneth Watts ,  Erik Joseph Sontheimer

IPC: C12N15/10 ,  C12N9/22 ,  C12N15/113 ,  C12N15/66 ,  C12N15/90

CPC classification number: C12N15/102 ,  C12N9/22 ,  C12N15/113 ,  C12N15/66 ,  C12N15/902

Abstract: The disclosure provides novel methods and compositions for gene editing. In particular, the disclosure relates to compositions and methods of making modified nucleic acid donor templates for highly efficient and precise gene editing.

公开(公告)号：US20240124870A1

公开(公告)日：2024-04-18

申请号：US18332029

申请日：2023-06-09

Applicant: UNIVERSITY OF MASSACHUSETTS

Inventor： Craig Cameron Mello ,  Krishna Sumanth Ghanta ,  Gregoriy Dokshin ,  Aamir Mir ,  Hassan Gneid ,  Jonathan Kenneth Watts ,  Erik Joseph Sontheimer

IPC: C12N15/10 ,  C12N9/22 ,  C12N15/113 ,  C12N15/66 ,  C12N15/90

CPC classification number: C12N15/102 ,  C12N9/22 ,  C12N15/113 ,  C12N15/66 ,  C12N15/902

Abstract: The disclosure provides novel methods and compositions for gene editing. In particular, the disclosure relates to compositions and methods of making modified nucleic acid donor templates for highly efficient and precise gene editing.