公开(公告)号：US20100106132A1

公开(公告)日：2010-04-29

申请号：US12260700

申请日：2008-10-29

Applicant: Thomas A. SIMONTON

Inventor： Thomas A. SIMONTON

IPC: A61M5/31

CPC classification number: A61M37/0069

Abstract: A drug cartridge is provided for delivering a drug pellet to a site beneath the skin of a patient, the drug cartridge comprising: two or more chambers, each chamber holding a drug pellet and having a proximal end and a distal end, the proximal end of the chamber having an opening to receive the drug pellet and a plunger, the distal end of the chamber having an opening for receiving the plunger and passage of the drug pellet, superior and inferior locking covers disposed on at least one chamber opening, wherein movement of the plunger to an extended position moves the drug pellet within the chamber of the cartridge out the distal end of the chamber and out of the drug cartridge. Devices that utilize the drug cartridge are also provided.

Abstract translation: 提供了药物盒，用于将药物丸粒输送到患者皮肤下方的部位，药物盒包括：两个或更多个腔室，每个腔室容纳药物丸粒并具有近端和远端，近端 所述腔室具有用于接收药物丸粒的开口和柱塞，所述腔室的远端具有用于接收所述柱塞并且所述药丸的通道的开口，设置在至少一个腔室开口上的上下锁定盖，其中， 柱塞到延伸位置将药筒内的药丸从药筒的远端移出药物盒。 还提供了利用药物盒的装置。

公开(公告)号：US20100106136A1

公开(公告)日：2010-04-29

申请号：US12260673

申请日：2008-10-29

Applicant: Thomas A. SIMONTON

Inventor： Thomas A. SIMONTON

IPC: A61M5/315

CPC classification number: A61M37/0069

Abstract: Drug depot delivery devices and methods for delivering a drug depot to a site beneath the skin of a patient are provided. In various embodiments, a device for delivering a drug depot to a site beneath the skin of a patient is provided, the device comprising: a cannula capable of insertion to the site beneath the skin of the patient and having an opening for passage of the drug depot; a drug cartridge comprising at least two chambers, wherein each chamber is configured to store and release a drug depot into the cannula when the cannula is aligned with a first chamber and the plunger. In some embodiments, the drug depot delivery device and methods provide slide-a-dose technology for delivering the drug depot to the target tissue site.

Abstract translation: 提供了用于将药剂库递送到患者皮肤下方的部位的药物库递送装置和方法。 在各种实施例中，提供了一种用于将药物储存器递送到患者皮肤下方的部位的装置，该装置包括：套管，能够插入患者皮肤下方的位置并具有用于药物通过的开口 仓库; 药筒，其包括至少两个腔室，其中每个腔室配置成当所述插管与第一腔室和所述柱塞对准时，将药物储存器储存并释放到所述套管中。 在一些实施方案中，药物储库递送装置和方法提供用于将药物贮库递送至靶组织部位的滑动一剂量技术。

公开(公告)号：US20100121310A1

公开(公告)日：2010-05-13

申请号：US12268075

申请日：2008-11-10

Applicant: Thomas A. SIMONTON ,  Sean M. HADDOCK ,  Lehmann K. LI

Inventor： Thomas A. SIMONTON ,  Sean M. HADDOCK ,  Lehmann K. LI

IPC: A61M5/31

CPC classification number: B01F15/0205 ,  B01F7/00075 ,  B01F11/0082 ,  B01F11/0091 ,  B01F13/002 ,  B01F13/0023 ,  B01F15/0215 ,  B01F15/0223 ,  B01F15/0279 ,  B01F2215/0027 ,  B01F2215/0029

Abstract: A multiple component cartridge includes a barrel defining a chamber and a longitudinal axis. A first plunger is disposed within the chamber and in sealing engagement with the barrel. The first plunger includes at least one member and is movable relative to the barrel such that the at least one member is configured for movement relative to the first plunger to facilitate passage of at least a first component through the first plunger. A second plunger is disposed within the chamber and in sealing engagement with the barrel. The second plunger includes at least one member and is movable relative to the barrel such that the at least one member of the second plunger is configured for movement relative to the second plunger to facilitate passage of at least a second component through the second plunger.

Abstract translation: 多部件盒包括限定腔室和纵向轴线的筒体。 第一柱塞设置在室内并与筒密封接合。 所述第一柱塞包括至少一个构件并且可相对于所述筒移动，使得所述至少一个构件被构造成相对于所述第一柱塞运动，以促进至少第一构件通过所述第一柱塞。 第二柱塞设置在腔室内并与枪管密封接合。 所述第二柱塞包括至少一个构件并且可相对于所述筒移动，使得所述第二柱塞的所述至少一个构件被构造成相对于所述第二柱塞移动以便于至少第二构件通过所述第二柱塞。

公开(公告)号：US20100114075A1

公开(公告)日：2010-05-06

申请号：US12262823

申请日：2008-10-31

Applicant: Thomas A. SIMONTON ,  Sean M. HADDOCK ,  John Myers ZANELLA ,  William F. MCKAY

Inventor： Thomas A. SIMONTON ,  Sean M. HADDOCK ,  John Myers ZANELLA ,  William F. MCKAY

IPC: A61K9/22

CPC classification number: A61M25/00 ,  A61B5/04001 ,  A61B5/4893 ,  A61M25/007 ,  A61M25/0084

Abstract: Drug depot delivery devices and methods are provided for delivering one or more drug depots to one or more sites beneath the skin of a patient with or without repositioning the cannula. The device has a cannula capable of insertion to the site beneath the skin of the patient and one or more side port openings for delivering a drug depot. The side port openings are spaced a distance from the blunt tip, which will allow the user to implant at a set distance from a nerve. The device may also include an electronic monitor for detecting the proximity of the tip of the cannula to a nerve. In some embodiments, a method of delivering a drug depot is provided by detecting the nerve and delivering the drug depot at or near the nerve.

Abstract translation: 提供药物库递送装置和方法用于将一个或多个药物储存器递送到具有或不具有重新定位插管的患者皮肤下方的一个或多个部位。 该装置具有能够插入到患者皮肤下方的部位的插管和用于递送药物库的一个或多个侧口开口。 侧端口与钝头间隔开一段距离，这将允许使用者以距离神经一定距离植入。 该装置还可以包括用于检测套管尖端与神经的接近的电子监视器。 在一些实施方案中，通过检测神经并将药物贮存库输送到神经中或附近来提供递送药物库的方法。