公开(公告)号：US20250060301A1

公开(公告)日：2025-02-20

申请号：US18915034

申请日：2024-10-14

Applicant: ThinkCyte K.K.

Inventor： Toru Imai ,  Keisuke Toda

IPC: G01N15/14 ,  G01N15/10 ,  G01N15/1433 ,  G01N15/1434

Abstract: A flow cytometer includes: a flow channel allowing a measurement object not labeled with a fluorescent dye to flow along with a fluid; a light source emitting illumination light; an illumination optical system irradiating the measurement object flowing in the flow channel with the illumination light emitted from the light source as a spotlight which is illumination light condensed in at least one of a width direction and a depth direction of the flow channel at an irradiation position in the flow channel; a light detector detecting fluorescence emitted from a specific molecule of the measurement object in response to irradiation with the spotlight via the illumination optical system; a detection optical system allowing the fluorescence to propagate to the light detector; and a discrimination unit configured to discriminate whether the measurement object is a target measurement object based on information of the fluorescence detected by the light detector.

公开(公告)号：US20230266229A1

公开(公告)日：2023-08-24

申请号：US18118670

申请日：2023-03-07

Applicant: ThinkCyte K.K.

Inventor： Toru Imai ,  Hiroaki Adachi ,  Keisuke Toda

IPC: G01N15/14

CPC classification number: G01N15/1459 ,  G01N15/1484 ,  G01N15/1436 ,  G01N2015/1006

Abstract: A flow cytometer includes: a light source; a microfluidic device; a photodetector; an information generation device which generates optical information indicating a morphology of an observation target on the basis of optical signal intensity; and a spatial light modulation unit which is installed on an optical path between the light source and the photodetector and structures any one of illumination light irradiated from the light source toward the flow path and signal light from the observation target. In the flow path provided with the microfluidic device, a plurality of optical signal detection positions are arranged linearly at equal intervals in a predetermined direction of the flow path by structuring the illumination light or the signal light and a plurality of trigger signal detection positions for detecting a trigger signal by which the information generation device starts the generation of the optical information are arranged to be separated by the same predetermined distance in a length direction of the flow path while respectively corresponding to the plurality of optical signal detection positions.