公开(公告)号：US20240295554A1

公开(公告)日：2024-09-05

申请号：US18378736

申请日：2023-10-11

申请人： The Walter and Eliza Hall Institute of Medical Research

发明人： Ivo Mueller ,  Takafumi Tsuboi ,  Michael White ,  Rhea Longley

IPC分类号： G01N33/569 ,  C07K14/415 ,  C07K16/20 ,  G01N33/68

CPC分类号： G01N33/56905 ,  C07K14/415 ,  C07K16/205 ,  G01N33/6857 ,  G01N2333/445

摘要： A system, method, apparatus and diagnostic test for Plasmodium vivax, to determine a likelihood of a specific timing of infection by P. vivax in a subject, and hence identify individuals with a high probability of being infected with otherwise undetectable liver-stage hypnozoites. The system, method, apparatus and diagnostic test relate to the identification of hypnozoites (“dormant” liver-stages), or at least of the likelihood of the subject being so infected. Optionally and preferably, the specific timing relates to recent infections, for example within the last 9 months.

公开(公告)号：US11835520B2

公开(公告)日：2023-12-05

申请号：US16472269

申请日：2017-12-21

申请人： The Walter and Eliza Hall Institute of Medical Research

发明人： Ivo Mueller ,  Takafumi Tsuboi ,  Michael White ,  Rhea Longley

IPC分类号： G01N33/573 ,  G01N33/569 ,  C07K14/415 ,  C07K16/20 ,  G01N33/68

CPC分类号： G01N33/56905 ,  C07K14/415 ,  C07K16/205 ,  G01N33/6857 ,  G01N2333/445

摘要： A system, method, apparatus and diagnostic test for Plasmodium vivax, to determine a likelihood of a specific timing of infection by P. vivax in a subject, and hence identify individuals with a high probability of being infected with otherwise undetectable liver-stage hypnozoites. The system, method, apparatus and diagnostic test relate to the identification of hypnozoites (“dormant” liver-stages), or at least of the likelihood of the subject being so infected. Optionally and preferably, the specific timing relates to recent infections, for example within the last 9 months.

公开(公告)号：US20210132063A1

公开(公告)日：2021-05-06

申请号：US16472269

申请日：2017-12-21

申请人： THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH

发明人： Ivo Mueller ,  Takafumi Tsuboi ,  Michael White ,  Rhea Longley

IPC分类号： G01N33/569 ,  C07K14/415 ,  C07K16/20 ,  G01N33/68

摘要： A system, method, apparatus and diagnostic test for Plasmodium vivax, to determine a likelihood of a specific timing of infection by P. vivax in a subject, and hence identify individuals with a high probability of being infected with otherwise undetectable liver-stage hypnozoites. The system, method, apparatus and diagnostic test relate to the identification of hypnozoites (“dormant” liver-stages), or at least of the likelihood of the subject being so infected. Optionally and preferably, the specific timing relates to recent infections, for example within the last 9 months.