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1.发明公开公开(公告)号：US20240156737A1
公开(公告)日：2024-05-16
申请号：US18391998
申请日：2023-12-21
发明人： Martina Kovarova , Soumya Rahima Benhabbour , J. Victor Garcia-Martinez , Panita Maturavongsadit
CPC分类号： A61K9/204 , A61K9/0024 , A61K9/2095 , A61K45/06
摘要： Disclosed herein are polymeric implants and controlled release drug delivery systems to provide high drug loading and long-acting drug release. Provided herein are methods for making the same. Methods of administering pharmacologically active agents via the disclosed polymeric implants and controlled release drug delivery systems are also provided.
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公开(公告)号：US20220105042A1
公开(公告)日：2022-04-07
申请号：US17427190
申请日：2020-01-31
发明人： Martina Kovarova , Soumya Rahima Benhabbour , J. Victor Garcia-Martinez , Panita Maturavongsadit
摘要： Disclosed herein are polymeric implants and controlled release drug delivery systems to provide high drug loading and long-acting drug release. Provided herein are methods for making the same. Methods of administering pharmacologically active agents via the disclosed polymeric implants and controlled release drug delivery systems are also provided.
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公开(公告)号：US20220330530A1
公开(公告)日：2022-10-20
申请号：US17642768
申请日：2020-09-11
IPC分类号： A01K67/027
摘要： Provided are non-human animals, including humanized bone marrow/liver/thymus (BLT) non-human animals, that include a recipient immunodeficient animal with human thymus tissue and human liver tissue, both implanted under a kidney capsule of the recipient immunodeficient animal, and transplanted hematopoietic stem cells derived from a human liver tissue. Such non-human animals have human thymus tissue and human liver tissue that are autologous with the hematopoietic stem cells derived from the human liver tissue. Methods of making such BLT non-human animals are also provided. Also disclosed herein are human immune system non-human animals and methods of making the same.
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