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公开(公告)号：US20240327400A1
公开(公告)日：2024-10-03
申请号：US18013808
申请日：2021-06-29
发明人： Daniel L. Sun , Michael E. Jung , Daniel Gil , William E. Lowry , Heather R. Christofk , Aimee Flores , Xiaoguang Liu
IPC分类号： C07D471/04 , A61P17/14
CPC分类号： C07D471/04 , A61P17/14
摘要： The present disclosure relates to novel compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
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公开(公告)号：US20200157093A1
公开(公告)日：2020-05-21
申请号：US16627630
申请日：2018-06-29
IPC分类号： C07D471/04 , A61K9/00 , A61P17/14 , C07D209/22 , C07D413/06 , C07D417/06 , C07F9/535
摘要： The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
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公开(公告)号：US11787804B2
公开(公告)日：2023-10-17
申请号：US17847980
申请日：2022-06-23
IPC分类号： C07D471/04 , A61P17/14 , A61K9/00 , C07D209/22 , C07D413/06 , C07D417/06 , C07F9/535
CPC分类号： C07D471/04 , A61K9/0014 , A61P17/14 , C07D209/22 , C07D413/06 , C07D417/06 , C07F9/535
摘要： The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
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公开(公告)号：US20220153738A1
公开(公告)日：2022-05-19
申请号：US17584091
申请日：2022-01-25
IPC分类号： C07D471/04 , C07D209/22 , C07D417/06
摘要： The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
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公开(公告)号：US20240025895A1
公开(公告)日：2024-01-25
申请号：US18241583
申请日：2023-09-01
IPC分类号： C07D471/04 , A61P17/14 , A61K9/00 , C07D209/22 , C07D413/06 , C07D417/06 , C07F9/535
CPC分类号： C07D471/04 , A61P17/14 , A61K9/0014 , C07F9/535 , C07D413/06 , C07D417/06 , C07D209/22
摘要： The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
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公开(公告)号：US20230190736A1
公开(公告)日：2023-06-22
申请号：US17917445
申请日：2021-04-09
发明人： Vaithilingaraja Arumugaswami , Heather R. Christofk , Robert Damoiseaux , Gustavo Garcia , Peter Mullen , Brigitte N. Gomperts
IPC分类号： A61K31/497 , A61K45/06 , A61P31/14 , A61K31/5377 , A61K31/436 , A61K31/4706
CPC分类号： A61K31/497 , A61K45/06 , A61P31/14 , A61K31/5377 , A61K31/436 , A61K31/4706
摘要： This disclosure relates to methods of treating viral infections, such as influenza or coronavirus, with certain inhibitors, such as kinase inhibitors.
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公开(公告)号：US11472804B2
公开(公告)日：2022-10-18
申请号：US17584091
申请日：2022-01-25
IPC分类号： C07D471/04 , A61P17/14 , A61K9/00 , C07D209/22 , C07D413/06 , C07D417/06 , C07F9/535
摘要： The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
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公开(公告)号：US20230114220A1
公开(公告)日：2023-04-13
申请号：US17847980
申请日：2022-06-23
IPC分类号： C07D471/04 , A61P17/14 , A61K9/00 , C07D209/22 , C07D413/06 , C07D417/06 , C07F9/535
摘要： The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
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公开(公告)号：US11312714B2
公开(公告)日：2022-04-26
申请号：US16627630
申请日：2018-06-29
IPC分类号： C07D471/04 , A61K9/00 , A61P17/14 , C07D209/22 , C07D413/06 , C07D417/06 , C07F9/535
摘要： The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
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公开(公告)号：US11213513B2
公开(公告)日：2022-01-04
申请号：US16488451
申请日：2017-08-25
摘要： Provided herein are methods of accelerating, promoting, or restoring hair growth, comprising administering to a subject in need thereof an effective amount of a compound of formula (I). Also provided are compositions comprising the compound of formula (I).
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