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公开(公告)号：US11607466B2
公开(公告)日：2023-03-21
申请号：US16471678
申请日：2017-12-21
摘要： The presently disclosed subject matter provides compositions, kits, and methods comprising imaging agents that can detect Programmed Death Ligand 1 (PD-L1). The presently disclosed imaging agents can be used to detect diseases and disorders, such as cancer, infection, and inflammation, in a subject.
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公开(公告)号：US10898594B2
公开(公告)日：2021-01-26
申请号：US15771786
申请日：2016-10-27
发明人： Wojciech Lesniak , Sridhar Nimmagadda , Nikita Oskolkov , Michael McMahon , Xiaolei Song , Martin G. Pomper
IPC分类号： A61K49/12 , A61K49/14 , A61K49/10 , A61K51/04 , C08G73/02 , C08G83/00 , C08G79/08 , A61K49/16 , A61K51/06
摘要： PAMAM dendrimer based CEST imaging agents, pharmaceutical compositions comprising the same and methods of uses thereof are disclosed.
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3.发明公开公开(公告)号：US20240293584A1
公开(公告)日：2024-09-05
申请号：US18585905
申请日：2024-02-23
CPC分类号： A61K51/0485 , A61K47/545 , A61K51/0478 , A61K51/0482
摘要： Imaging and radiotherapeutics agents targeting fibroblast-activation protein-α (FAP-α) and their use in imaging and treating FAP-α related diseases and disorders are disclosed.
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4.发明授权公开(公告)号：US11938201B2
公开(公告)日：2024-03-26
申请号：US18354282
申请日：2023-07-18
CPC分类号： A61K51/0485 , A61K47/545 , A61K51/0478 , A61K51/0482
摘要： Imaging and radiotherapeutics agents targeting fibroblast-activation protein-α (FAP-α) and their use in imaging and treating FAP-α related diseases and disorders are disclosed.
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5.发明公开公开(公告)号：US20230364274A1
公开(公告)日：2023-11-16
申请号：US18354282
申请日：2023-07-18
CPC分类号： A61K51/0485 , A61K47/545 , A61K51/0478 , A61K51/0482
摘要： Imaging and radiotherapeutics agents targeting fibroblast-activation protein-α (FAP-α) and their use in imaging and treating FAP-α related diseases and disorders are disclosed.
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公开(公告)号：US20230271923A1
公开(公告)日：2023-08-31
申请号：US18040858
申请日：2021-08-06
IPC分类号： C07D209/04 , G01N33/534 , G01N33/543 , G01N33/569
CPC分类号： C07D209/04 , G01N33/534 , G01N33/54326 , G01N33/54346 , G01N33/56911 , G01N2800/7095
摘要： The presently disclosed subject matter provides compositions, kits, and methods comprising imaging agents that can detect Programmed Cell Death Ligand 1 (PD-L1). The presently disclosed imaging agents can be used to detect diseases and disorders, such as cancer, infection, and inflammation, in a subject.
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公开(公告)号：US20190314531A1
公开(公告)日：2019-10-17
申请号：US16471678
申请日：2017-12-21
摘要： The presently disclosed subject matter provides compositions, kits, and methods comprising imaging agents that can detect Programmed Death Ligand 1 (PD-L1). The presently disclosed imaging agents can be used to detect diseases and disorders, such as cancer, infection, and inflammation, in a subject.
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公开(公告)号：US12115233B2
公开(公告)日：2024-10-15
申请号：US18585905
申请日：2024-02-23
CPC分类号： A61K51/0485 , A61K47/545 , A61K51/0478 , A61K51/0482
摘要： Imaging and radiotherapeutics agents targeting fibroblast-activation protein-α (FAP-α) and their use in imaging and treating FAP-α related diseases and disorders are disclosed.
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9.发明申请公开(公告)号：US20200330624A1
公开(公告)日：2020-10-22
申请号：US16758182
申请日：2018-10-23
摘要： Imaging and radiotherapeutics agents targeting fibroblast-activation protein-α (FAP-α) and their use in imaging and treating FAP-α related diseases and disorders are disclosed.
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