Patent search ap:("The Broad Institute Page Inc.") AND inv:"Fanny Lazzaro"

1.

发明授权
Cycloalkenyl hydroxamic acid derivatives and their use as histone deacetylase inhibitors 有权

公开(公告)号：US10793538B2

公开(公告)日：2020-10-06

申请号：US15878694

申请日：2018-01-24

Applicant: The Broad Institute, Inc.

Inventor： Edward Holson , Fanny Lazzaro , David Olson , Florence Fevrier Wagner , Michel Weiwer

IPC: C07D309/28 , C07C259/08 , C07C323/61 , C07D209/08 , C07D211/78 , C07D211/96 , C07D263/16

Abstract: The present invention provides compounds of formula (I): or a pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein W, X, n, s, t, and Ra are as described herein. The present invention relates generally to selective inhibitors of histone deacetylase and to methods of making and using them.

2.

发明授权
Cycloalkenyl hydroxamic acid derivatives and their use as histone deacetylase inhibitors 有权

公开(公告)号：US09914717B2

公开(公告)日：2018-03-13

申请号：US14654296

申请日：2013-12-19

Applicant: The Broad Institute, Inc.

Inventor： Edward Holson , Fanny Lazzaro , David Olson , Florence Fevrier Wagner , Michel Weiwer

IPC: C07D309/28 , C07C259/08 , C07C323/61 , C07D263/16 , C07D209/08 , C07D211/78 , C07D211/96

CPC classification number: C07D309/28 , C07C259/08 , C07C323/61 , C07C2601/10 , C07C2601/16 , C07C2602/08 , C07C2602/10 , C07D209/08 , C07D211/78 , C07D211/96 , C07D263/16

Abstract: The present invention provides compounds of formula (I) or a pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein W, X, n, s, t, and Ra are as described herein. The present invention relates generally to selective inhibitors of histone deacetylase and to methods of making and using them.

3.

发明申请
CYCLOALKENYL HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS HISTONE DEACETYLASE INHIBITORS 审中-公开

公开(公告)号：US20180215726A1

公开(公告)日：2018-08-02

申请号：US15878694

申请日：2018-01-24

Applicant: The Broad Institute, Inc.

Inventor： Edward Holson , Fanny Lazzaro , David Olson , Florence Fevrier Wagner , Michel Weiwer

IPC: C07D309/28 , C07D211/96 , C07C259/08 , C07C323/61 , C07D209/08 , C07D211/78 , C07D263/16

Abstract: The present invention provides compounds of formula (I): or a pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein W, X, n, s, t, and Ra are as described herein. The present invention relates generally to selective inhibitors of histone deacetylase and to methods of making and using them.

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