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公开(公告)号：US11472787B2
公开(公告)日：2022-10-18
申请号：US16648945
申请日：2018-09-20
发明人： Aditi Das , Jahnabi Roy
IPC分类号： C07D331/02 , C07D303/46 , C07D203/12 , A61P29/00
摘要： The present disclosure provides novel compounds derived from docosahexaenoic acid endocannabinoid epoxides having anti-cancer, anti-inflammatory, anti-platelet aggregation and anti-angiogenic properties. Methods of synthesizing and using the compositions are also provided.
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2.发明申请LIPOPROTEIN NANOPLATELETS: FLUORESCENT, ZWITTERIONIC PROBES FOR MOLECULAR AND CELLULAR IMAGING 审中-公开LIPOPROTEIN NANOPLATELETS：荧光，分子和细胞成像的ZWITTERICIC PROBES公开(公告)号：US20170059575A1
公开(公告)日：2017-03-02
申请号：US15244026
申请日：2016-08-23
发明人： Andrew Smith , Sung Jun Lim , Aditi Das
CPC分类号： G01N33/588 , A61K49/0067 , G01N33/5032
摘要： Compositions are provided comprising water-stable semi-conductor nanoplatelets encapsulated in a hydrophilic coating further comprising lipids and lipoproteins. Uses include biomolecular imaging and sensing, and methods of making comprise: colloidal synthesis of CdSe core NPLs; layer-by-layer growth of a CdS shell; and encapsulation of CdSe/CdScore/shell NPLs in lipid and lipoprotein components through an evaporation-encapsulation using zwitterionic phospholipids, detergents, and amphipathic membrane scaffold proteins.
摘要翻译： 提供的组合物包含包封在还包含脂质和脂蛋白的亲水涂层中的水稳定性半导体纳米片。 用途包括生物分子成像和感测，制作方法包括：CdSe核心不良物质的胶体合成; CdS壳的逐层生长; 并通过使用两性离子磷脂，洗涤剂和两亲性膜支架蛋白的蒸发封装将CdSe / CdScore /壳NPLs包封在脂质和脂蛋白组分中。
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公开(公告)号：US20200247777A1
公开(公告)日：2020-08-06
申请号：US16648953
申请日：2018-09-20
发明人： Aditi Das , Josephine E. Watson
IPC分类号： C07D331/02 , C07D303/46 , C07D203/08 , A61P29/00
摘要： The present disclosure provides chemical compound derivatives of a class of biological lipid mediators known as endocannabinoids and methods of synthesizing the compositions. These compounds are useful for treating cancer, reducing inflammation, reducing platelet aggregation, and reducing angiogenesis.
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公开(公告)号：US11407728B2
公开(公告)日：2022-08-09
申请号：US16648953
申请日：2018-09-20
发明人： Aditi Das , Josephine E. Watson
IPC分类号： C07D331/02 , C07D303/46 , C07D203/08 , A61P29/00
摘要： The present disclosure provides chemical compound derivatives of a class of biological lipid mediators known as endocannabinoids and methods of synthesizing the compositions. These compounds are useful for treating cancer, reducing inflammation, reducing platelet aggregation, and reducing angiogenesis.
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公开(公告)号：US20200247776A1
公开(公告)日：2020-08-06
申请号：US16648945
申请日：2018-09-20
发明人： Aditi Das , Jahnabi Roy
IPC分类号： C07D331/02 , C07D303/46 , C07D203/12 , A61P29/00
摘要： The present disclosure provides novel compounds derived from docosahexaenoic acid endocamabinoid epoxides having anti-cancer, anti-inflammatory, anti-platelet aggregation and anti-angiogenic properties. Methods of synthesizing and using the compositions are also provided.
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6.发明授权公开(公告)号：US10209258B2
公开(公告)日：2019-02-19
申请号：US15244026
申请日：2016-08-23
发明人： Andrew Smith , Sung Jun Lim , Aditi Das
摘要： Compositions are provided comprising water-stable semi-conductor nanoplatelets encapsulated in a hydrophilic coating further comprising lipids and lipoproteins. Uses include biomolecular imaging and sensing, and methods of making comprise: colloidal synthesis of CdSe core NPLs; layer-by-layer growth of a CdS shell; and encapsulation of CdSe/CdScore/shell NPLs in lipid and lipoprotein components through an evaporation-encapsulation using zwitterionic phospholipids, detergents, and amphipathic membrane scaffold proteins.
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