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公开(公告)号：US20240201208A1
公开(公告)日：2024-06-20
申请号：US18527954
申请日：2023-12-04
申请人： Tecan Trading AG
发明人： Michael Keller , Thomas Geiges , Volfgang Vilaj
CPC分类号： G01N35/00584 , G01N35/04 , G01N2035/0434
摘要： A method for determining physical parameters of an unknown liquid to be aspirated and/or dispensed by a laboratory automation device comprises: determining physical parameters of a pipette, the physical parameters including geometric parameters of the pipette, which at least include a tip radius of an orifice of the pipette; aspirating and/or dispensing the unknown liquid with a pipette of the laboratory automation device and measuring a measured pressure curve in the pipette during aspirating and/or dispensing; determining the physical parameters of the unknown liquid by minimizing an objective function depending on a difference between a simulated pressure curve and the measured pressure curve, wherein the simulated pressure curve simulates a pressure in the pipette during aspirating and/or dispensing and is calculated based on a physical model of the laboratory automation device including the physical parameters of the pipette.
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公开(公告)号：US20240201219A1
公开(公告)日：2024-06-20
申请号：US18528347
申请日：2023-12-04
申请人： Tecan Trading AG
发明人： Michael Keller , Thomas Geiges , Volfgang Vilaj
CPC分类号： G01N35/1009 , G01N11/00 , G01N13/02 , G01N2013/0208
摘要： A method for determining physical parameters of a liquid to be aspirated and/or dispensed by a laboratory automation device comprises: picking up of a pipette with the laboratory automation device; lowering the pipette into a sample container with the laboratory automation device, the sample container containing the liquid; aspirating and dispensing air and liquid with the laboratory automation device in such a way, that a liquid level in the pipette solely rises in a first step and solely lowers in a second step, such that an interior surface of the pipette is wetted with liquid solely one time; and during aspirating and dispensing air and liquid, measuring a pressure curve in the pipette and determining the physical parameters from the pressure curve, the physical parameters comprising at least one of a surface tension, a wetting angle and a viscosity.
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