-
公开(公告)号：US20190169166A1
公开(公告)日：2019-06-06
申请号：US16323863
申请日：2017-08-09
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Jun FUJIMOTO , Xin LIU , Osamu KURASAWA , Terufumi TAKAGI , Douglas Robert CARY , Hiroshi BANNO , Yasutomi ASANO , Takuto KOJIMA
IPC: C07D401/12 , C07D239/42 , A61P35/00
Abstract: Provided is a heterocyclic compound that may have a GCN2 inhibitory action, and is expected to be useful for the prophylaxis or treatment of GCN2 associated diseases including cancer and the like. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.
-
公开(公告)号：US20180170874A1
公开(公告)日：2018-06-21
申请号：US15565891
申请日：2016-04-19
Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventor： Yasutomi ASANO , Takuto KOJIMA , Osamu KURASAWA , Tzu-Tshin WONG , Yasuhiro HIRATA , Naoki IWAMURA , Bunnai SAITO , Yuta TANAKA , Ryosuke ARAI , Shinichi IMAMURA , Kazuko YONEMORI , Yasufumi MIYAMOTO , Shuji KITAMURA , Osamu SANO
IPC: C07D211/58 , C07D471/04 , C07D498/04 , C07D513/04 , C07D519/00 , C07D215/42 , C07D401/12 , C07D417/12 , C07D405/06 , C07D413/06 , C07D401/06 , C07D417/06 , C07D401/14 , C07D417/14 , C07D413/14 , C07B59/00 , A61P35/00 , A61P3/00
CPC classification number: C07D211/58 , A61K31/437 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/4468 , A61K31/451 , A61K31/452 , A61K31/4709 , A61K31/498 , A61K31/506 , A61K31/517 , A61K31/5355 , A61K31/661 , A61K33/22 , A61P3/00 , A61P35/00 , C07B59/002 , C07B2200/05 , C07D215/42 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/06 , C07D409/12 , C07D413/06 , C07D413/14 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D498/04 , C07D513/04 , C07D519/00 , C07F5/02 , C07F9/6509
Abstract: The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease).
-
公开(公告)号：US20170209452A1
公开(公告)日：2017-07-27
申请号：US15484755
申请日：2017-04-11
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Misaki HOMMA , Toru MIYAZAKI , Yuya OGURO , Osamu KURASAWA
IPC: A61K31/519 , A61K31/541 , A61K31/55 , A61K31/5377
CPC classification number: A61K31/519 , A61K31/5377 , A61K31/541 , A61K31/55 , C07D495/04 , C07D498/20
Abstract: Provided is a compound useful for the prophylaxis or treatment of cancer.The present invention relates to a compound represented by formula (I): wherein each symbol in the formula is as defined in the specification, or a salt thereof or a prodrug thereof, which is useful for the prophylaxis or treatment of cancer.
-
Patent Agency Ranking
公开(公告)号：US20150158882A1
公开(公告)日：2015-06-11
申请号：US14566157
申请日：2014-12-10
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Misaki HOMMA , Toru MIYAZAKI , Yuya OGURO , Osamu KURASAWA
IPC: C07D495/04 , C07D498/20
CPC classification number: A61K31/519 , A61K31/5377 , A61K31/541 , A61K31/55 , C07D495/04 , C07D498/20
Abstract: Provided is a compound useful for the prophylaxis or treatment of cancer.The present invention relates to a compound represented by formula (I): wherein each symbol in the formula is as defined in the specification, or a salt thereof or a prodrug thereof, which is useful for the prophylaxis or treatment of cancer.
Abstract translation: 提供一种可用于预防或治疗癌症的化合物。 本发明涉及由式（I）表示的化合物：其中式中的每个符号如本说明书中所定义，或其盐或其前药，其可用于预防或治疗癌症。
-
公开(公告)号：US20140235615A1
公开(公告)日：2014-08-21
申请号：US14223329
申请日：2014-03-24
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Misaki HOMMA , Toru MIYAZAKI , Yuya OGURO , Osamu KURASAWA
IPC: C07D498/20 , C07D495/04
CPC classification number: A61K31/519 , A61K31/5377 , A61K31/541 , A61K31/55 , C07D495/04 , C07D498/20
Abstract: Provided is a compound useful for the prophylaxis or treatment of cancer.The present invention relates to a compound represented by formula (I): wherein each symbol in the formula is as defined in the specification, or a salt thereof or a prodrug thereof, which is useful for the prophylaxis or treatment of cancer.
Abstract translation: 提供一种可用于预防或治疗癌症的化合物。 本发明涉及由式（I）表示的化合物：其中式中的每个符号如本说明书中所定义，或其盐或其前药，其可用于预防或治疗癌症。
-
公开(公告)号：US20190062274A1
公开(公告)日：2019-02-28
申请号：US16175144
申请日：2018-10-30
Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventor： Yasutomi ASANO , Takuto KOJIMA , Osamu KURASAWA , Tzu-Tshin WONG , Yasuhiro HIRATA , Naoki IWAMURA , Bunnai SAITO , Yuta TANAKA , Ryosuke ARAI , Shinichi IMAMURA , Kazuko YONEMORI , Yasufumi MIYAMOTO , Shuji KITAMURA , Osamu SANO
IPC: C07D211/58 , C07F9/6509 , C07D405/06 , A61P3/00 , A61P35/00 , C07B59/00 , C07D413/14 , C07F5/02 , C07D519/00 , C07D513/04 , C07D498/04 , C07D487/04 , C07D471/04 , C07D417/14 , C07D417/12 , C07D417/06 , C07D413/06 , C07D409/12 , C07D401/12 , C07D401/06 , C07D215/42 , A61K33/22 , A61K31/661 , A61K31/5355 , A61K31/517 , A61K31/506 , A61K31/498 , A61K31/4709 , A61K31/452 , A61K31/451 , A61K31/4468 , A61K31/444 , A61K31/4439 , A61K31/4436 , A61K31/4433 , A61K31/443 , A61K31/437 , C07D401/14
CPC classification number: C07D211/58 , A61K31/437 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/4468 , A61K31/451 , A61K31/452 , A61K31/4709 , A61K31/498 , A61K31/506 , A61K31/517 , A61K31/5355 , A61K31/661 , A61K33/22 , A61P3/00 , A61P35/00 , C07B59/002 , C07B2200/05 , C07D215/42 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/06 , C07D409/12 , C07D413/06 , C07D413/14 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D498/04 , C07D513/04 , C07D519/00 , C07F5/02 , C07F9/6509 , Y02P20/55
Abstract: The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease).
-
公开(公告)号：US20160310494A1
公开(公告)日：2016-10-27
申请号：US15176893
申请日：2016-06-08
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Misaki HOMMA , Toru MIYAZAKI , Yuya OGURO , Osamu KURASAWA
IPC: A61K31/519 , A61K31/541 , A61K31/55 , A61K31/5377
CPC classification number: A61K31/519 , A61K31/5377 , A61K31/541 , A61K31/55 , C07D495/04 , C07D498/20
Abstract: Provided is a compound useful for the prophylaxis or treatment of cancer.The present invention relates to a compound represented by formula (I): wherein each symbol in the formula is as defined in the specification, or a salt thereof or a prodrug thereof, which is useful for the prophylaxis or treatment of cancer.
Abstract translation: 其中式中的每个符号如说明书中所定义，或其盐或其前药，其可用于预防或治疗癌症。
-
公开(公告)号：US20140228352A1
公开(公告)日：2014-08-14
申请号：US14223259
申请日：2014-03-24
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Misaki HOMMA , Toru MIYAZAKI , Yuya OGURO , Osamu KURASAWA
IPC: C07D495/04 , C07D498/20
CPC classification number: A61K31/519 , A61K31/5377 , A61K31/541 , A61K31/55 , C07D495/04 , C07D498/20
Abstract: Provided is a compound useful for the prophylaxis or treatment of cancer.The present invention relates to a compound represented by formula (I): wherein each symbol in the formula is as defined in the specification, or a salt thereof or a prodrug thereof, which is useful for the prophylaxis or treatment of cancer.
-
-
-
-
-
-
-
Search Results
8
records
(took 0.033 seconds)
