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公开(公告)号:US06552246B1
公开(公告)日:2003-04-22
申请号:US08451318
申请日:1995-05-26
IPC分类号: A61K67027
CPC分类号: C12N15/8509 , A01K2217/05 , A01K2227/105 , A01K2267/0387 , A61K38/00 , C07K14/70503 , C07K14/70521 , C07K14/70589
摘要: A mammal lacking expression of particular CD45 isoform in certain cells of the immune system is provided. The mammal may optionally contain a transgene encoding the CD45RO isoform. Also provided are methods of using these mammals.
摘要翻译: 提供了在免疫系统的某些细胞中缺乏特异性CD45同种型表达的哺乳动物。 哺乳动物可以任选地含有编码CD45RO同种型的转基因。 还提供了使用这些哺乳动物的方法。
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公开(公告)号:US6034230A
公开(公告)日:2000-03-07
申请号:US303862
申请日:1999-05-03
CPC分类号: C07K14/4716 , A61K38/00
摘要: Disclosed are novel peptides that modulate inflammatory heart disease. Also disclosed are DNA molecules encoding the peptides, and methods of making the peptides.
摘要翻译: 公开了调节炎性心脏病的新型肽。 还公开了编码肽的DNA分子和制备肽的方法。
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公开(公告)号:US5962636A
公开(公告)日:1999-10-05
申请号:US133774
申请日:1998-08-12
CPC分类号: C07K14/4716 , A61K38/00
摘要: Disclosed are novel peptides that modulate inflammatory heart disease. Also disclosed are DNA molecules encoding the peptides, and methods of making the peptides.
摘要翻译: 公开了调节炎性心脏病的新型肽。 还公开了编码肽的DNA分子和制备肽的方法。
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