公开(公告)号：US09265970B2

公开(公告)日：2016-02-23

申请号：US13393418

申请日：2011-03-02

Applicant: Taizo Honda ,  Masahiro Ikeda

Inventor： Taizo Honda ,  Masahiro Ikeda

IPC: H01J3/26 ,  A61N5/10

CPC classification number: A61N5/1043 ,  A61N5/1067 ,  A61N5/1068 ,  A61N2005/1059 ,  A61N2005/1087 ,  A61N2005/1095

Abstract: A particle beam irradiation system comprises deflection electromagnets which scan by deflecting the particle beam in two dimensions in the lateral direction which is perpendicular to an irradiation direction of the particle beam, and an energy width expanding device through which the particle beam passes so as to expand an energy width of the particle beam and form a SOBP in a depth direction of the irradiation target, that is, in an irradiation direction of the particle beam, wherein the energy width expanding device is configured to form the SOBP in the depth direction along whole irradiation area in the depth direction of the irradiation target, and the deflection electromagnets are controlled so as for an irradiation spot which is formed in the irradiation target by the particle beam to move stepwise along whole irradiation area in the lateral direction of the irradiation target.

Abstract translation: 粒子束照射系统包括偏转电磁体，该偏转电磁体通过在与粒子束的照射方向垂直的横向方向上的二维偏转粒子束进行扫描;以及能量扩大装置，粒子束通过该能量扩张装置以扩展 粒子束的能量宽度，并且在照射对象的深度方向，即在粒子束的照射方向上形成SOBP，其中，能量宽度扩展装置被构造成沿着整个深度方向形成SOBP 照射对象的深度方向的照射区域，并且对于通过粒子束形成在照射对象物上的照射点，控制偏转电磁体，沿着照射对象的横向的整个照射区域逐步移动。

公开(公告)号：US08854048B2

公开(公告)日：2014-10-07

申请号：US13262866

申请日：2011-03-10

Applicant: Toshihiro Otani ,  Hisashi Harada ,  Masahiro Ikeda ,  Kazushi Hanakawa ,  Taizo Honda

Inventor： Toshihiro Otani ,  Hisashi Harada ,  Masahiro Ikeda ,  Kazushi Hanakawa ,  Taizo Honda

IPC: G01N27/62 ,  A61N5/10

CPC classification number: H01J37/304 ,  A61N5/1048 ,  A61N5/1071 ,  A61N5/1077 ,  A61N2005/1087 ,  H01J47/02

Abstract: In a particle beam therapy system which scans a particle beam and irradiates the particle beam to an irradiation position of an irradiation subject and has a dose monitoring device for measuring a dose of the particle beam and an ionization chamber smaller than the dose monitoring device, the ionization chamber measuring a dose of a particle beam passing through the dose monitoring device, the dose of the particle beam irradiated by the dose monitoring device is measured; the dose of the particle beam passing through the dose monitoring device is measured by the small ionization chamber; and a correction coefficient of the dose measured by the dose monitoring device corresponding to the irradiation position is found based on the dose of the particle beam measured by the small ionization chamber.

Abstract translation: 在粒子束治疗系统中，扫描粒子束并将粒子束照射到照射对象的照射位置，并且具有用于测量粒子束的剂量和小于剂量监测装置的电离室的剂量监测装置， 电离室测量通过剂量监测装置的粒子束的剂量，测量由剂量监测装置照射的粒子束的剂量; 通过小电离室测量通过剂量监测装置的粒子束的剂量; 并且基于由小电离室测量的粒子束的剂量，求出由与照射位置对应的剂量监测装置测量的剂量的校正​​系数。

公开(公告)号：US20140228615A1

公开(公告)日：2014-08-14

申请号：US14240650

申请日：2011-11-03

Applicant: Masahiro Ikeda ,  Hisashi Harada ,  Kazushi Hanakawa ,  Toshihiro Otani ,  Tadashi Katayose ,  Taizo Honda ,  Yukiko Yamada ,  Yuehu Pu

Inventor： Masahiro Ikeda ,  Hisashi Harada ,  Kazushi Hanakawa ,  Toshihiro Otani ,  Tadashi Katayose ,  Taizo Honda ,  Yukiko Yamada ,  Yuehu Pu

IPC: A61N5/10

CPC classification number: A61N5/1081 ,  A61N5/1077 ,  A61N2005/1087 ,  A61N2005/1095

Abstract: A particle beam irradiation apparatus according to the present invention is provided with a vacuum duct that forms a vacuum region through which the charged particle beam passes, a vacuum window through which the charged particle beam is launched from the vacuum region, a scanning electromagnet that scans the charged particle beam; a monitoring apparatus including a position monitor that detects the passing position of a charged particle beam and the beam size thereof, a low-scattering gas filling chamber including the monitoring apparatus, and an irradiation management apparatus that controls irradiation of the charged particle beam; the particle beam irradiation apparatus is characterized in that the low-scattering gas filling chamber is changeably disposed in such a manner that the beam-axis-direction positional relationship between the monitoring apparatus and the vacuum window is a desired one and in that the low-scattering gas filling chamber is filled with a low-scattering gas.

Abstract translation: 根据本发明的粒子束照射装置设置有真空管道，该真空管道形成带电粒子束通过的真空区域，从真空区域发射带电粒子束的真空窗口，扫描的扫描电磁体 带电粒子束; 监视装置，其包括检测带电粒子束的通过位置的位置监视器及其光束尺寸，包括监视装置的低散射气体填充室以及控制带电粒子束的照射的照射管理装置; 所述粒子束照射装置的特征在于，所述低散射气体充填室可变地设置成使得所述监视装置和所述真空窗口之间的射束轴向位置关系是期望的， 散射气体填充室填充有低散射气体。

公开(公告)号：US20140187847A1

公开(公告)日：2014-07-03

申请号：US14240197

申请日：2011-11-02

Applicant: Masahiro Ikeda ,  Hisashi Harada ,  Kazushi Hanakawa ,  Toshihiro Otani ,  Tadashi Katayose ,  Taizo Honda ,  Yukiko Yamada ,  Yuehu Pu

Inventor： Masahiro Ikeda ,  Hisashi Harada ,  Kazushi Hanakawa ,  Toshihiro Otani ,  Tadashi Katayose ,  Taizo Honda ,  Yukiko Yamada ,  Yuehu Pu

IPC: A61N5/10

CPC classification number: A61N5/1077 ,  A61N5/1049 ,  A61N5/1069 ,  A61N2005/1087

Abstract: A particle beam therapy system comprising a treatment table, a treatment table control unit and an irradiation control unit configured to output an instruction for controlling the treatment table control unit, an accelerator and a scanning electromagnet, wherein after the treatment table control unit controls the treatment table so as for a patient isocenter which is reference position of an affected area of a patient to move to a position of an irradiation isocenter which is set at a position which is closer to an irradiation nozzle than an equipment isocenter which is reference of positional relation of the irradiation nozzle and the treatment table, the irradiation control unit outputs an instruction for irradiating the patient with a particle beam.

Abstract translation: 一种粒子束治疗系统，包括治疗台，治疗台控制单元和照射控制单元，其被配置为输出用于控制治疗台控制单元的指令，加速器和扫描电磁体，其中在治疗台控制单元控制治疗 将患者的中心位置作为患者的受影响区域的基准位置移动到被设定在比作为位置关系的参照的设备等角点更靠近照射喷嘴的位置的照射等角点的位置 的照射喷嘴和处理台，照射控制单元输出用于对粒子束照射患者的指示。

公开(公告)号：US20130289333A1

公开(公告)日：2013-10-31

申请号：US13977093

申请日：2011-03-07

Applicant: Kengo Sugahara ,  Masahiro Ikeda ,  Kazushi Hanakawa ,  Taizo Honda ,  Hisashi Harada

Inventor： Kengo Sugahara ,  Masahiro Ikeda ,  Kazushi Hanakawa ,  Taizo Honda ,  Hisashi Harada

IPC: A61N5/10

CPC classification number: A61N5/1077 ,  A61N5/1043 ,  A61N2005/1074 ,  A61N2005/1087

Abstract: The present invention is intended to enable proper elimination of the remanent magnetization of the scanning magnet, which is used in a particle beam therapy system, in a short time. In the particle beam therapy system that irradiates an irradiation target with a particle beam 18 accelerated by an accelerator and scanned by scanning magnets 11 and 12, power supplies 13 and 14 to operate the scanning magnets 11 and 12 output pattern currents for demagnetizing the scanning magnets 11 and 12. The pattern current is controlled by a control circuit 15 that reads a demagnetization pattern 17 and controls the power supplies 13 and 14.

Abstract translation: 本发明旨在能够在短时间内适当消除用于粒子束治疗系统的扫描磁体的剩余磁化。 在用由加速器加速并通过扫描磁体11和12扫描的粒子束18照射照射目标的粒子束治疗系统中，用于操作扫描磁体11和12的电源13和14输出用于使扫描磁体去磁的图案电流 图案电流由读取去磁图案17并控制电源13和14的控制电路15控制。

公开(公告)号：US08421031B2

公开(公告)日：2013-04-16

申请号：US13258772

申请日：2011-03-10

Applicant: Taizo Honda ,  Masahiro Ikeda ,  Yuehu Pu ,  Kazushi Hanakawa

Inventor： Taizo Honda ,  Masahiro Ikeda ,  Yuehu Pu ,  Kazushi Hanakawa

IPC: H01J3/26 ,  A61N5/10

CPC classification number: A61N5/1043 ,  A61N5/1048 ,  A61N5/1077 ,  A61N2005/1074 ,  A61N2005/1087

Abstract: The objective is to obtain a particle beam therapy system that can suppress the effect of a leakage dose. There are provided a scanning nozzle that irradiates in a predetermined direction a particle beam emitted from an accelerator; an irradiation control unit that controls operation of the irradiation nozzle in such a way that the particle beam of a predetermined dose is sequentially irradiated onto each of a plurality of spots set in a planar direction in an irradiation subject; and a control unit that on/off-controls emission of the particle beam from the accelerator. The irradiation control unit makes the irradiation nozzle scan in a diluting manner the particle beam onto a predetermined area in the irradiation subject, in a predetermined period after a time point when emission is switched from ON to OFF, or in a period from the time point when emission is switched from ON to OFF to a time point when the particle beam is cut off.

Abstract translation: 目的是获得能够抑制泄漏剂量影响的粒子束治疗系统。 提供了沿预定方向照射从加速器发射的粒子束的扫描喷嘴; 照射控制单元，其以照射对象的平面方向上设置的多个点顺序地照射预定剂量的粒子束的方式控制照射喷嘴的动作; 以及控制单元，其控制来自加速器的粒子束的发射。 照射控制单元使得照射喷嘴在发射从ON切换到OFF之后的预定时间内或在从时间点开始的时间段内，将粒子束以稀释的方式扫描到照射对象的预定区域上 当发射从ON切换到截止到粒子束的时间点时。

公开(公告)号：US20120223247A1

公开(公告)日：2012-09-06

申请号：US13393418

申请日：2011-03-02

Applicant: Taizo Honda ,  Masahiro Ikeda

Inventor： Taizo Honda ,  Masahiro Ikeda

IPC: H01J3/26

CPC classification number: A61N5/1043 ,  A61N5/1067 ,  A61N5/1068 ,  A61N2005/1059 ,  A61N2005/1087 ,  A61N2005/1095

Abstract: A particle beam irradiation system comprises deflection electromagnets which scan by deflecting the particle beam in two dimensions in the lateral direction which is perpendicular to an irradiation direction of the particle beam, and an energy width expanding device through which the particle beam passes so as to expand an energy width of the particle beam and form a SOBP in a depth direction of the irradiation target, that is, in an irradiation direction of the particle beam, wherein the energy width expanding device is configured to form the SOBP in the depth direction along whole irradiation area in the depth direction of the irradiation target, and the deflection electromagnets are controlled so as for an irradiation spot which is formed in the irradiation target by the particle beam to move stepwise along whole irradiation area in the lateral direction of the irradiation target.

Abstract translation: 粒子束照射系统包括偏转电磁体，该偏转电磁体通过在垂直于粒子束的照射方向的横向方向上的二维偏转粒子束进行扫描;以及能量扩大装置，粒子束通过该能量扩展装置以扩展 粒子束的能量宽度，并且在照射对象的深度方向，即在粒子束的照射方向上形成SOBP，其中，能量宽度扩展装置被构造成沿着整个深度方向形成SOBP 照射对象的深度方向的照射区域，并且对于通过粒子束形成在照射对象物上的照射点，控制偏转电磁体，沿着照射对象的横向的整个照射区域逐步移动。

公开(公告)号：US09067066B2

公开(公告)日：2015-06-30

申请号：US14356629

申请日：2012-03-27

Applicant: Yukiko Yamada ,  Hisashi Harada ,  Taizo Honda ,  Masahiro Ikeda ,  Kazushi Hanakawa ,  Toshihiro Otani ,  Tadashi Katayose

Inventor： Yukiko Yamada ,  Hisashi Harada ,  Taizo Honda ,  Masahiro Ikeda ,  Kazushi Hanakawa ,  Toshihiro Otani ,  Tadashi Katayose

IPC: G21K5/04 ,  A61N5/10

CPC classification number: A61N5/1048 ,  A61N5/1043 ,  A61N5/1077 ,  A61N2005/1074 ,  A61N2005/1087 ,  H05H13/04 ,  H05H2277/11

Abstract: A control unit is provided with, a retaining section that retains a plurality of operation patterns each being a pattern of operation to be periodically repeated by an accelerator, the operation patterns having respective operation conditions adjusted for different emission times of an particle beam, to cause a deflection electromagnet in the accelerator to have an intended magnetic field intensity even under a presence of a hysteresis; a reading section for a plurality of slices of an irradiation target in a depth direction, which reads an irradiation condition for each of the slices; a selection section that selects the operation pattern suitable for each of the slices, on the basis of the read irradiation condition; and a main control section that controls, for each of the slices, the accelerator on the basis of the selected operation pattern and an irradiation device on the basis of the irradiation condition.

Abstract translation: 控制单元设置有保持部，其保持多个操作模式，每个操作模式是由加速器周期性重复的操作模式，所述操作模式具有针对粒子束的不同发射次数调整的各自的操作条件，以使得 加速器中的偏转电磁体即使在滞后的情况下也具有预期的磁场强度; 用于读取每个切片的照射条件的用于在深度方向上的照射目标的多个切片的读取部分; 选择部，其基于读取的照射条件选择适合于每个切片的操作模式; 以及主控制部，其基于所述照射条件，基于所选择的操作模式和照射装置对每个切片进行加速器的控制。

公开(公告)号：US20150038766A1

公开(公告)日：2015-02-05

申请号：US14386626

申请日：2012-03-21

Applicant: Yuehu PU ,  Masahiro Ikeda ,  Taizo Honda

Inventor： Yuehu PU ,  Masahiro Ikeda ,  Taizo Honda

IPC: A61N5/10

CPC classification number: A61N5/1071 ,  A61N5/103 ,  A61N5/1031 ,  A61N5/1043 ,  A61N2005/1087

Abstract: A particle beam scanning irradiation method includes the steps of calculating a planned irradiating particle count of a particle beam for each of irradiation spots, on the basis of a relative amount of particle beam irradiation and a prescription particle-beam dose determined from a particle-beam therapy plan; simulating an irradiation process of the particle beam at each irradiation spot, on the basis of the planned irradiating particle count and a beam current waveform of the particle beam, and calculating a particle count of the particle beam irradiating the diseased portion during a scan shift of the particle beam; correcting the planned irradiating particle count for each irradiation spot by using the irradiating particle count during the scan shift; converting the corrected planned-irradiation particle count into a count value used in a dose monitor; and irradiating the irradiation spot with the particle beam, on the basis of the converted count value.

Abstract translation: 粒子束扫描照射方法包括以下步骤：基于粒子束照射的相对量和从粒子束确定的处方粒子束剂量来计算每个照射点的粒子束的计划照射粒子数 治疗方案; 基于所计划的照射粒子数和粒子束的束电流波形，模拟在各照射点处的粒子束的照射过程，计算在扫描位移期间照射患病部位的粒子束的粒子数 粒子束; 通过使用扫描偏移期间的照射粒子数来校正每个照射点的计划照射粒子数; 将校正的计划照射粒子数转换为剂量监视器中使用的计数值; 并且基于转换后的计数值，用粒子束照射照射点。

公开(公告)号：US08933420B2

公开(公告)日：2015-01-13

申请号：US14240197

申请日：2011-11-02

Applicant: Masahiro Ikeda ,  Hisashi Harada ,  Kazushi Hanakawa ,  Toshihiro Otani ,  Tadashi Katayose ,  Taizo Honda ,  Yukiko Yamada ,  Yuehu Pu

Inventor： Masahiro Ikeda ,  Hisashi Harada ,  Kazushi Hanakawa ,  Toshihiro Otani ,  Tadashi Katayose ,  Taizo Honda ,  Yukiko Yamada ,  Yuehu Pu

IPC: A61N5/10

CPC classification number: A61N5/1077 ,  A61N5/1049 ,  A61N5/1069 ,  A61N2005/1087

Abstract: A particle beam therapy system comprising a treatment table, a treatment table control unit and an irradiation control unit configured to output an instruction for controlling the treatment table control unit, an accelerator and a scanning electromagnet, wherein after the treatment table control unit controls the treatment table so as for a patient isocenter which is reference position of an affected area of a patient to move to a position of an irradiation isocenter which is set at a position which is closer to an irradiation nozzle than an equipment isocenter which is reference of positional relation of the irradiation nozzle and the treatment table, the irradiation control unit outputs an instruction for irradiating the patient with a particle beam.

Abstract translation: 一种粒子束治疗系统，包括治疗台，治疗台控制单元和照射控制单元，其被配置为输出用于控制治疗台控制单元的指令，加速器和扫描电磁体，其中在治疗台控制单元控制治疗 将患者的中心位置作为患者的受影响区域的基准位置移动到被设定在比作为位置关系的参照的设备等角点更靠近照射喷嘴的位置的照射等角点的位置 的照射喷嘴和处理台，照射控制单元输出用于对粒子束照射患者的指示。