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1.发明申请Oligonucleotides and method for characterizing and detecting genogroup II type small round structured virus 审中-公开用于表征和检测基因组II型小圆结构病毒的寡核苷酸和方法公开(公告)号：US20040063096A1
公开(公告)日：2004-04-01
申请号：US10678124
申请日：2003-10-06
Applicant: TOSOH CORPORATION
Inventor： Noriyoshi Masuda , Takahiko Ishiguro , Juichi Saito , Toshiki Taya , Kiyoshi Yasukawa
IPC: C12Q001/70 , C12Q001/68 , C07H021/04 , C07H021/02
CPC classification number: C12Q1/701
Abstract: Nucleic acid sequences, oligonucleotides and a method for detection of SRSV, in particular, a virus which belongs to Genotype II (GII), in clinical examinations, public health examinations, food evaluations and food poisoning examinations are provided.
Abstract translation: 提供了核酸序列，寡核苷酸和用于检测SRSV的方法，特别是属于基因型II（GII）的病毒，用于临床检查，公众健康检查，食物评估和食物中毒检查。
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公开(公告)号：US20030008278A1
公开(公告)日：2003-01-09
申请号：US10126611
申请日：2002-04-22
Applicant: TOSOH CORPORATION
Inventor： Tetsuya Ishizuka , Kiyoshi Yasukawa , Takahiko Ishiguro
IPC: C12Q001/70 , C12Q001/68 , C12P019/34
CPC classification number: C12Q1/703
Abstract: A simple, speedy and sensitive method of detecting HIV-RNA using an oligonucleotide which can bind to an intramolecularly free region of the genomic RNA of HIV-1 at relatively low and constant temperatures (at 35null C. to 50null C., preferably at 41null C.) as an oligonucleotide primer for use in amplification of a nucleic acid.
Abstract translation: 使用寡核苷酸检测HIV-RNA的简单，快速和灵敏的方法，所述寡核苷酸可以在相对低的和恒定的温度（在35℃至50℃，优选地）结合HIV-1的基因组RNA的分子内游离区域 在41℃）作为用于核酸扩增的寡核苷酸引物。
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公开(公告)号：US20040202998A1
公开(公告)日：2004-10-14
申请号：US10804002
申请日：2004-03-19
Applicant: TOSOH CORPORATION
Inventor： Tetsuya Ishizuka , Kiyoshi Yasukawa , Takahiko Ishiguro
IPC: C12Q001/70 , C12P019/34
CPC classification number: C12Q1/703
Abstract: A simple, speedy and sensitive method of detecting HIV-RNA using an oligonucleotide which can bind to an intramolecularly free region of the genomic RNA of HIV-1 at relatively low and constant temperatures (at 35null C. to 50null C., preferably at 41null C.) as an oligonucleotide primer for use in amplification of a nucleic acid.
Abstract translation: 使用寡核苷酸检测HIV-RNA的简单，快速和灵敏的方法，所述寡核苷酸可以在相对低的和恒定的温度（在35℃至50℃，优选地）结合HIV-1的基因组RNA的分子内游离区域 在41℃）作为用于核酸扩增的寡核苷酸引物。
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公开(公告)号：US20030219729A1
公开(公告)日：2003-11-27
申请号：US10382328
申请日：2003-03-06
Applicant: TOSOH CORPORATION
Inventor： Kiyoshi Yasukawa , Takahiko Ishiguro
IPC: C12Q001/70 , C12Q001/68 , C12P019/34 , C12N009/22
CPC classification number: C12N9/1276
Abstract: An avian myeloblastosis virus reverse transcriptase composition which comprises a heterodimer consisting of an null subunit having a molecular weight of 68000 and a null subunit having a molecular weight of 92000 in an amount of at least 80%.
Abstract translation: 一种禽成髓细胞病毒病毒逆转录酶组合物，其包含由分子量为68000的α亚单位组成的异源二聚体和分子量为92000的β亚基，其量至少为80％。
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5.发明申请Oligonucleotides and method for characterizing and detecting genogroup II type small round structured virus 失效用于表征和检测基因组II型小圆结构病毒的寡核苷酸和方法公开(公告)号：US20020099201A1
公开(公告)日：2002-07-25
申请号：US09989002
申请日：2001-11-21
Applicant: TOSOH CORPORATION
Inventor： Noriyoshi Masuda , Takahiko Ishiguro , Juichi Saito , Toshiki Taya , Kiyoshi Yasukawa
IPC: C12Q001/70 , C12Q001/68 , C07H021/04
CPC classification number: C12Q1/701
Abstract: Nucleic acid sequences, oligonucleotides and a method for detection of SRSV, in particular, a virus which belongs to Genotype II (GII), in clinical examinations, public health examinations, food evaluations and food poisoning examinations are provided.
Abstract translation: 提供了核酸序列，寡核苷酸和用于检测SRSV的方法，特别是属于基因型II（GII）的病毒，用于临床检查，公众健康检查，食物评估和食物中毒检查。
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Patent Agency Ranking
公开(公告)号：US20040170604A1
公开(公告)日：2004-09-02
申请号：US10806422
申请日：2004-03-23
Applicant: TOSOH CORPORATION
Inventor： Teiji Ekida , Harutaka Yagame , Hiroshi Iida , Kiyoshi Yasukawa , Shigeo Tsuchiya , Teruhiko Ide
IPC: A61K038/20 , C07H021/04 , C12P021/04 , C12N001/18 , C12N015/74
CPC classification number: C12N5/0647 , A61K38/00 , C07K14/5412 , C07K14/7155 , C07K2319/00 , C12N2501/125
Abstract: The present invention intends to provide an IL-6RnullIL-6 fusion protein and the like in which IL-6R and IL-6 are directly linked without a linker. The IL-6 receptornullIL-6 fusion protein of the present invention has a structure in which one amino acid residue constituting IL-6 receptor and one amino acid residue constituting IL-6 are directly bonded.
Abstract translation: 本发明意图提供IL-6R.IL-6融合蛋白等，其中IL-6R和IL-6直接连接而不连接。 本发明的IL-6受体-IL-6融合蛋白具有构成IL-6受体的一个氨基酸残基和构成IL-6的一个氨基酸残基直接结合的结构。
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7.发明申请公开(公告)号：US20040161783A1
公开(公告)日：2004-08-19
申请号：US10737894
申请日：2003-12-18
Applicant: TOSOH CORPORATION
Inventor： Noriyoshi Masuda , Yuichi Isawa , Ryuichi Horie , Kiyoshi Yasukawa
IPC: C12Q001/68
CPC classification number: C12Q1/689
Abstract: A method of detecting a specific acid-fast bacterium, wherein primers having nucleotide sequences homologous or complementary to the specific regions in the rRNAs of the specific acid-fast bacterium are used to specifically amplify only the rRNAs of the specific acid-fast bacterium.
Abstract translation: 检测特异性耐酸细菌的方法，其中使用具有与特异性耐酸细菌的rRNA中的特定区域同源或互补的核苷酸序列的引物仅特异性扩增特异性耐酸细菌的rRNA。
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8.发明申请Oligonucleotides and method for characterizing and detecting Genogroup II type small round structured virus 失效用于表征和检测Genogroup II型小圆结构病毒的寡核苷酸和方法公开(公告)号：US20030180894A1
公开(公告)日：2003-09-25
申请号：US10441126
申请日：2003-05-20
Applicant: TOSOH CORPORATION
Inventor： Noriyoshi Masuda , Takahiko Ishiguro , Juichi Saito , Toshiki Taya , Kiyoshi Yasukawa
IPC: C12Q001/68 , C12P019/34 , C12N005/06 , C12N005/16
CPC classification number: C12Q1/701
Abstract: Nucleic acid sequences, oligonucleotides and a method for detection of SRSV, in particular, a virus which belongs to Genotype II (GII), in clinical examinations, public health examinations, food evaluations and food poisoning examinations are provided.
Abstract translation: 提供了核酸序列，寡核苷酸和用于检测SRSV的方法，特别是属于基因型II（GII）的病毒，用于临床检查，公众健康检查，食物评估和食物中毒检查。
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9.发明申请Oligonucleotide for detection of atypical mycobacteria mycobacterium avium and detection method 审中-公开用于检测非典型分枝杆菌鸟分枝杆菌的寡核苷酸和检测方法公开(公告)号：US20030219811A1
公开(公告)日：2003-11-27
申请号：US10403090
申请日：2003-04-01
Applicant: TOSOH CORPORATION
Inventor： Noriyoshi Masuda , Kiyoshi Yasukawa , Takahiko Ishiguro
IPC: C12Q001/68 , C07H021/04 , C12P019/34
CPC classification number: C12Q1/689 , C12Q1/6865
Abstract: An oligonucleotide for detection of the Pst S-3 gene of an atypical mycobacterium Mycobacterium avium or an RNA derived from the gene consisting of at least 10 bases in any of SEQ ID NOS:1 to 12, which can bind to a specific site of the gene or the RNA.
Abstract translation: 用于检测非典型分枝杆菌鸟分枝杆菌的Pst S-3基因的寡核苷酸或源自由SEQ ID NO：1至12中任一项中至少10个碱基组成的基因的RNA，其可以结合到 基因或RNA。
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公开(公告)号：US20030219730A1
公开(公告)日：2003-11-27
申请号：US10391631
申请日：2003-03-20
Applicant: TOSOH CORPORATION
Inventor： Kiyoshi Yasukawa , Takahiko Ishiguro
IPC: C12Q001/70 , C07H021/04
CPC classification number: C12Q1/701
Abstract: A cDNA sequence of any one of SEQ ID NOS:1 to 4 or a derivative thereof, which binds to a genogroup I small round-structured virus genome, or a fragment of a cDNA sequence of any one of SEQ ID NOS:1 to 4 or a derivative thereof, which is large enough to bind to a genogroup I small round-structured virus genome.
Abstract translation: SEQ ID NO：1至4中任一项的cDNA序列或其衍生物，其结合到基因组I小圆结构病毒基因组，或SEQ ID NO：1至4中任一个的cDNA序列的片段 或其衍生物，其足够大以结合基因组I小圆形结构病毒基因组。
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