公开(公告)号：US20240325529A1

公开(公告)日：2024-10-03

申请号：US18573750

申请日：2022-06-22

Applicant: TORAY INDUSTRIES, INC.

Inventor： Fumiyoshi OKANO ,  Daisuke AKAZAWA

IPC: A61K39/395 ,  A61K31/282 ,  A61K31/7068 ,  A61K33/243 ,  A61P35/00

CPC classification number: A61K39/3955 ,  A61K31/282 ,  A61K31/7068 ,  A61K33/243 ,  A61P35/00

Abstract: A medicament characterized by comprising: an antibody or a fragment thereof having an immunological reactivity with CAPRIN-1 protein; a pyrimidine-based drug; a platinum formulation; and an angiogenesis inhibitor together or separately in combination is useful as a medicament for treatment and/or prevention of a cancer of a cancer patient having a medical history of another treatment of the cancer.

公开(公告)号：US20230165957A1

公开(公告)日：2023-06-01

申请号：US17910532

申请日：2021-03-11

Applicant: TORAY INDUSTRIES, INC.

Inventor： Fumiyoshi OKANO ,  Daisuke AKAZAWA

IPC: A61K39/395 ,  A61P35/04 ,  A61K33/243 ,  A61K31/7068

CPC classification number: A61K39/3955 ,  A61P35/04 ,  A61K33/243 ,  A61K31/7068

Abstract: An object of the present invention is to provide a medicament for treatment and/or prevention of cancer. The present invention provides a medicament for treatment and/or prevention of cancer in a cancer patient with a previous history of another cancer treatment, comprising an antibody or a fragment thereof having an immunological reactivity with CAPRIN-1 protein, and a pyrimidine-based drug and cisplatin together or separately in combination.

公开(公告)号：US20140046034A1

公开(公告)日：2014-02-13

申请号：US14060157

申请日：2013-10-22

Applicant: Japan as Represented by Director-General of National Institute of Infectious Diseases ,  TORAY INDUSTRIES, INC.

Inventor： Takaji WAKITA ,  Kazumi NISHIMURA ,  Noriko NAKAMURA ,  Daisuke AKAZAWA

IPC: C07K16/10

CPC classification number: C07K16/109 ,  A61K2039/505 ,  C07K2317/30 ,  C07K2317/76

Abstract: An object of the present invention is to provide an antibody inhibiting infection with hepatitis C virus (HCV). The present invention provides an anti-hepatitis C virus antibody that recognizes a whole or a part of the conformation of a hepatitis C virus particle as an epitope and binds thereto, so as to be able to inhibit the binding of hepatitis C virus to the surface of a host cell and to inhibit HCV infection, a humanized antibody thereof, and an inhibitory agent for infection with hepatitis C virus.

Abstract translation: 本发明的目的是提供抗丙型肝炎病毒（HCV）的抗体抑制感染。 本发明提供一种抗丙型肝炎病毒抗体，其识别丙型肝炎病毒颗粒的构象的全部或一部分作为表位并与其结合，从而能够抑制丙型肝炎病毒与表面的结合 的宿主细胞并抑制HCV感染，其人源化抗体和用于感染丙型肝炎病毒的抑制剂。

公开(公告)号：US20230129035A1

公开(公告)日：2023-04-27

申请号：US17910538

申请日：2021-03-11

Applicant: TORAY INDUSTRIES, INC.

Inventor： Fumiyoshi OKANO ,  Daisuke AKAZAWA

IPC: C07K16/28 ,  A61K31/337 ,  A61P35/00 ,  C07K16/22

Abstract: An object of the preset invention is to provide a medicament for treatment and/or prevention of cancer. The present invention relates to a medicament for treatment and/or prevention of cancer in a cancer patient with a previous history of another cancer treatment, comprising an antibody or a fragment thereof haying an immunological reactivity with CAPRIN-1 protein, and an angiogenesis inhibitor or an angiogenesis inhibitor and a taxane-based drug together or separately in combination.