专利检索 ap:("THE UNIVERSITY OF CHICAGO") AND inv:"Michal RACZY" 第 1 页

1.

发明公开
METHODS AND COMPOSITIONS FOR TREATING DISORDERS WITH ORAL SYSTEMICALLY BIOAVAILABLE BUTYRATE CONJUGATES 审中-公开

公开(公告)号：US20240207213A1

公开(公告)日：2024-06-27

申请号：US18556006

申请日：2022-04-18

申请人： THE UNIVERSITY OF CHICAGO

发明人： Jeffrey HUBBELL , Shijie CAO , Michal RACZY , Elyse WATKINS , Erica BUDINA

IPC分类号： A61K31/221 , A61K9/00 , A61P37/00

CPC分类号： A61K31/221 , A61K9/0053 , A61P37/00

摘要： Described herein are novel methods of treating disorders using oral, systemically bioavailable forms of butyrate. Aspects of the disclosure relate to a method for treating a disorder in a subject comprising administering the oral, systemically bioavailable composition to the subject, wherein the disorder is selected from inflammatory bowel disease (IBD), multiple sclerosis (MS), a neuroinflammatory condition, food allergies, rheumatoid arthritis (RA), asthma, celiac disease, non-alcoholic steatohepatitis (NASH), diabetes, Alzheimer's disease (AD), inflammaging, beta-hemoglobinopathies, vascular inflammatory conditions, atopic dermatitis and psoriasis, pulmonary fibrosis, and systemic sclerosis.