公开(公告)号：US20210015422A1

公开(公告)日：2021-01-21

申请号：US16866208

申请日：2020-05-04

Applicant: THE GENERAL HOSPITAL CORPORATION

Inventor： Patrick L. Purdon ,  Eran A. Mukamel ,  Emery N. Brown

IPC: A61B5/00 ,  A61B5/0478 ,  A61B5/048 ,  A61B5/04

Abstract: A system and method for monitoring and/or controlling a state of consciousness of a subject experiencing anesthesia are provided. In some aspects, the system includes a plurality of sensors placed about the subject and configured to acquire electroencephalogram (“EEG”) data therefrom while the subject is receiving anesthesia, and at least one processor configured to receive the EEG data from the plurality of sensors, and perform a phase-amplitude coupling analysis using the received EEG data to determine a phase-amplitude frequency distribution. The at least one processor is also configured to identify a state of consciousness of the subject using the determined phase-amplitude frequency distribution, and generate a report indicative of the state of consciousness of the subject.

公开(公告)号：US11751770B2

公开(公告)日：2023-09-12

申请号：US16165580

申请日：2018-10-19

Applicant: The General Hospital Corporation

Inventor： Emery N. Brown ,  Patrick L. Purdon ,  Aylin Cimenser ,  Eran A. Mukamel ,  Michael J. Prerau

IPC: A61B5/00 ,  A61B5/0205 ,  G16H50/70 ,  G16H50/20 ,  G06F17/18 ,  A61B5/369 ,  A61B5/374 ,  A61B5/02 ,  A61B5/38

CPC classification number: A61B5/0205 ,  A61B5/369 ,  A61B5/374 ,  A61B5/4821 ,  A61B5/7246 ,  G06F17/18 ,  G16H50/20 ,  G16H50/70 ,  A61B5/02 ,  A61B5/38 ,  A61B5/7264 ,  G06F2218/00

Abstract: A method and system for determining the state of a patients brain under anesthesia. The present invention recognizes that anesthesia compounds induce different signatures in physiological characteristics of the patient under anesthesia and aids interpretation of physiological characteristics and signatures therein based on a selected anesthesia compound. The present invention aids the monitoring and/or interpreting of the physiological characteristics to a state of the patient's brain.

公开(公告)号：US10674956B2

公开(公告)日：2020-06-09

申请号：US15111002

申请日：2015-01-14

Applicant: THE GENERAL HOSPITAL CORPORATION

Inventor： Patrick L. Purdon ,  Eran A. Mukamel ,  Emery N. Brown

IPC: A61B5/00 ,  A61B5/04 ,  A61B5/0478 ,  A61B5/048

Abstract: A system and method for monitoring and/or controlling a state of consciousness of a subject experiencing anesthesia are provided. In some aspects, the system includes a plurality of sensors placed about the subject and configured to acquire electroencephalogram (“EEG”} data therefrom while the subject is receiving anesthesia, and at least one processor configured to receive the EEG data from the plurality of sensors, and perform a phase-amplitude coupling analysis using the received EEG data to determine a phase-amplitude frequency distribution. The at least one processor is also configured to identify a state of consciousness of the subject using the determined phase-amplitude frequency distribution, and generate a report indicative of the state of consciousness of the subject.

公开(公告)号：US20190117085A1

公开(公告)日：2019-04-25

申请号：US16165580

申请日：2018-10-19

Applicant: The General Hospital Corporation

Inventor： Emery N. Brown ,  Patrick L. Purdon ,  Aylin Cimenser ,  Eran A. Mukamel ,  Michael J. Prerau

IPC: A61B5/0205 ,  G06K9/00 ,  A61B5/00 ,  A61B5/048 ,  A61B5/0476

Abstract: A method and system for determining the state of a patients brain under anesthesia. The present invention recognizes that anesthesia compounds induce different signatures in physiological characteristics of the patient under anesthesia and aids interpretation of physiological characteristics and signatures therein based on a selected anesthesia compound. The present invention aids the monitoring and/or interpreting of the physiological characteristics to a state of the patient's brain.

公开(公告)号：US20160331307A1

公开(公告)日：2016-11-17

申请号：US15111002

申请日：2015-01-14

Applicant: THE GENERAL HOSPITAL CORPORATION

Inventor： Patrick L. Purdon ,  Eran A. Mukamel ,  Emery N. Brown

IPC: A61B5/00 ,  A61B5/0478 ,  A61B5/04 ,  A61B5/048

CPC classification number: A61B5/4821 ,  A61B5/04015 ,  A61B5/0478 ,  A61B5/048 ,  A61B5/4839 ,  A61B5/7246 ,  A61B5/742

Abstract: A system and method for monitoring and/or controlling a state of consciousness of a subject experiencing anesthesia are provided. In some aspects, the system includes a plurality of sensors placed about the subject and configured to acquire electroencephalogram (“EEG”} data therefrom while the subject is receiving anesthesia, and at least one processor configured to receive the EEG data from the plurality of sensors, and perform a phase-amplitude coupling analysis using the received EEG data to determine a phase-amplitude frequency distribution. The at least one processor is also configured to identify a state of consciousness of the subject using the determined phase-amplitude frequency distribution, and generate a report indicative of the state of consciousness of the subject.

Abstract translation: 提供了一种用于监测和/或控制经历麻醉的受试者的意识状态的系统和方法。 在一些方面，所述系统包括围绕所述对象放置的多个传感器，并被配置为在所述对象正在接收麻醉时从其获取脑电图（“EEG”），以及配置成从所述多个传感器接收所述EEG数据的至少一个处理器 并且使用所接收的EEG数据执行相位幅度耦合分析以确定相位幅度频率分布，所述至少一个处理器还被配置为使用所确定的相位幅度频率分布来识别所述对象的意识状态，以及 产生一个指示主体意识状态的报告。