公开(公告)号：US20230190655A1

公开(公告)日：2023-06-22

申请号：US17291588

申请日：2019-11-12

申请人： THE GENERAL HOSPITAL CORPORATION

发明人： Orhun K. MURATOGLU ,  Ebru ORAL ,  Ali Eren ATICI

IPC分类号： A61K9/16 ,  A61K31/7036 ,  A61J3/00 ,  B29B9/16 ,  B29B9/10

CPC分类号： A61K9/1641 ,  A61K31/7036 ,  A61K9/1682 ,  A61J3/00 ,  B29B9/16 ,  B29B9/10 ,  B29K2105/0011

摘要： Methods of making consolidated blend(s) of polymeric material(s) with one or more therapeutic agents (such as an antibiotic) are provided, wherein the method comprises the steps of providing a polymeric material, blending the polymeric material with one or more therapeutic agent(s), pelletizing the blended polymeric material, environmentally treating by various approaches the pelletized polymeric material, and consolidating the environmentally treated pellet. Products made by the methods and uses of the products also are provided.

公开(公告)号：US20210395472A1

公开(公告)日：2021-12-23

申请号：US16635105

申请日：2018-08-28

申请人： THE GENERAL HOSPITAL CORPORATION

发明人： Ebru ORAL ,  Ayse Bakar ATICI ,  Ali Eren ATICI ,  Orhuri K. MURATOGLU

IPC分类号： C08J3/28 ,  C08L23/06 ,  C08K5/132 ,  C08F220/20 ,  C08F255/02 ,  C08F2/48 ,  C08J3/24

摘要： Methods of making crosslinked polymeric materials and crosslinked interlocked hybrid polymeric materials using photoinitiator, antioxidant, additive, and photoirradiation of polymeric blend and/or interlocked hybrid materials are provided. Methods of spatially controlling macroscopic properties and morphology of polymeric materials, and products made by the methods also are provided.