公开(公告)号：US20230154564A1

公开(公告)日：2023-05-18

申请号：US17985660

申请日：2022-11-11

Applicant: Tata Consultancy Services Limited

Inventor： Mohammed Monzoorul HAQUE ,  Sharmila Shekhar MANDE ,  Swadha ANAND

IPC: G16B25/10 ,  G16B45/00 ,  G16B30/10 ,  G16B50/30

CPC classification number: G16B25/10 ,  G16B45/00 ,  G16B30/10 ,  G16B50/30

Abstract: This disclosure relates generally to methods and systems for designing a personalized composition that can counteract or reduce skin malodor. Conventional techniques that prepare compositions to treat specific malodorants are limited and such compositions cannot be personalized to an individual according to the type of malodorant produced on skin of the individual. The present disclosure provides a method for designing a personalized composition for degrading the malodorant present in skin of the subject. First, a biological sample from the subject is collected, and metabolite composition of the sample is determined. next, one or more malodorant in the sample are identified based on the metabolite composition. Further, a combination of bacteria capable of degrading the identified malodorant are identified using the microbe-malodorant microbial knowledge base and lastly the personalized composition of the identified bacteria is designed using the combination of bacteria.

公开(公告)号：US20170308645A1

公开(公告)日：2017-10-26

申请号：US15268245

申请日：2016-09-16

Applicant: Tata Consultancy Services Limited

Inventor： Sharmila Shekhar MANDE ,  Mohammed Monzoorul HAQUE ,  Tungadri BOSE ,  Anirban DUTTA ,  Venkata Siva Kumar Reddy CHENNAREDDY

IPC: G06F19/24 ,  G06F19/22

CPC classification number: G16B40/00 ,  G16B30/00

Abstract: A method and system is provided for representing compositional properties of a biological sequence fragment and application thereof. The present application provides a method and system for representing compositional properties of a biological sequence fragment using a unidimensional compositional metric; comprising of collecting a plurality of biological sequence fragments; sequencing collected plurality of biological sequence fragments; generating a first set of reference vectors; computing a unidimensional compositional metric for each sequenced biological sequence fragment out of the plurality of sequenced biological sequence fragments as a cumulative function of the distance of the tetra-nucleotide frequency vector (v) from three or more reference vectors selected out of the generated first set of reference vectors; and segregating each sequenced biological sequence fragment out of the plurality of sequenced biological sequence fragments in to a plurality of groups based on respective unidimensional compositional metric.

公开(公告)号：US20240355443A1

公开(公告)日：2024-10-24

申请号：US18602287

申请日：2024-03-12

Applicant: Tata Consultancy Services Limited

Inventor： Tungadri BOSE ,  Harrisham KAUR ,  Rashmi SINGH ,  Anirban DUTTA ,  Mohammed Monzoorul HAQUE ,  Sharmila Shekhar MANDE

IPC: G16H20/10 ,  G06N20/20 ,  G16H10/40 ,  G16H10/60 ,  G16H50/30 ,  G16H50/70

CPC classification number: G16H20/10 ,  G06N20/20 ,  G16H10/40 ,  G16H10/60 ,  G16H50/30 ,  G16H50/70

Abstract: The present disclosure is related to a method and system for stratification of subjects as one of responders or non-responders to a therapy. It is imperative to critically evaluate the baseline/initial microbiome structure and composition of individuals and stratifying them before prescribing any microbiome-based drug/dietary interventions. The method identifies a panel of biological features/indicators/markers/signatures that can accurately stratify/classify/group individuals into responders and non-responders (for a given microbiome-based drug/therapy) based upon the differences in the metabolic functions of the gut microbial communities between the baseline gut microbiome profile (i.e. before the administration of an intervention) and after treatment gut microbiome profile (i.e. after the administration of the intervention). Individuals with samples showing an improvement in gut-health status after the administration of the pre-biotic intervention were tagged as responders and the rest were tagged as non-responders.

公开(公告)号：US20190046105A1

公开(公告)日：2019-02-14

申请号：US16076622

申请日：2017-02-15

Applicant: Tata Consultancy Services Limited

Inventor： Sharmila Shekhar MANDE ,  Mohammed Monzoorul HAQUE ,  Anirban DUTTA ,  Nishal Kumar PINNA ,  Mitali MERCHANT

IPC: A61B5/00 ,  C12Q1/689 ,  G06F19/12

Abstract: System and method for assessing preterm delivery risk for pregnant subject is disclosed. Existing preterm delivery risk assessment methods provide results in late second or third trimester of pregnancy, so little time is available for medical advice. Presently disclosed method and system predict preterm delivery risk within 15 weeks of pregnancy. Microbiome characterization data obtained from microbiome sample from pregnant subject. ‘Microbial taxonomic abundance profile’ generated from microbiome characterization data, contains abundance values of microbes present in the microbiome sample. ‘Taxonomic Composition Skew’ value, and distribution characteristic value for ‘microbial taxonomic abundance profile’, quantifying biases in abundance values of microbes from the microbial taxonomic abundance profile, is computed. Risk of preterm delivery is determined based on the distribution characteristic value or ‘taxonomic composition skew’ value of the set DSR, wherein the set DSR comprises values quantifying biases in the abundance values of microbes from the microbiome sample.

公开(公告)号：US20140244592A1

公开(公告)日：2014-08-28

申请号：US14157728

申请日：2014-01-17

Applicant: TATA CONSULTANCY SERVICES LIMITED

Inventor： Sharmila Shekhar MANDE ,  Anirban DUTTA ,  Tungadri BOSE ,  Mohammed Monzoorul HAQUE

IPC: G06F17/30

CPC classification number: G06F17/30073 ,  G06F17/30153 ,  H03M7/3059

Abstract: The present subject matter discloses a system and a method for data archival. A data archiving system comprises a processor and a compression module coupled to the processor and configured to compress an original data file to generate, for each level of lossy compression, a compressed base file and a patch file. The base file is generated using a lossy compression technique. The patch file for a particular level of lossy compression is generated using information lost at the particular level of lossy compression. The data archiving system further comprises a data archiving module coupled to the processor. The data archiving system is configured to save a last base file and a plurality of patch files corresponding to each level of lossy compression, where the last base file is the base file corresponding to a last level of lossy compression.

Abstract translation: 本主题公开了一种用于数据归档的系统和方法。 数据归档系统包括处理器和耦合到处理器的压缩模块，并且被配置为压缩原始数据文件，以针对每个有损压缩级别生成压缩的基本文件和补丁文件。 使用有损压缩技术生成基本文件。 使用在有损压缩的特定级别丢失的信息生成特定级别的有损压缩的补丁文件。 数据归档系统还包括耦合到处理器的数据归档模块。 数据归档系统被配置为保存最后的基本文件和对应于每个有损压缩级别的多个补丁文件，其中最后的基本文件是与最后一级有损压缩相对应的基本文件。