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公开(公告)号：US10029122B2
公开(公告)日：2018-07-24
申请号：US15176025
申请日：2016-06-07
摘要： The invention comprises a system for controlling a charged particle beam shape and direction relative to a controlled and dynamically positioned patient and/or an imaging surface, such as a scintillation plate of a tomography system and/or a first two-dimensional imaging system coupled to a second two-dimensional imaging system. Multiple interlinked beam/patient/imaging control stations allow safe zone operation and clear interaction with the charged particle beam system and the patient. Both treatment and imaging are facilitated using automated sequences controlled with a work-flow control system.
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公开(公告)号：US10118052B2
公开(公告)日：2018-11-06
申请号：US15727596
申请日：2017-10-07
摘要： The invention comprises a method for installing a proton based cancer therapy system in a hospital related brownfield building, comprising the steps of: (1) transporting gantry system elements to a basement of the brownfield, the gantry system comprising: a rotatable gantry support; a gantry counterweight; a rotatable gantry arm, and a main bearing, comprising: a diameter of at least ten feet, a first circular segment, comprising a first arc-to-chord section, a second circular segment, comprising a second arc-to-chord section, and an intermediate section; (2) transporting through a pre-existing elevator shaft in the hospital related brownfield building the main bearing in a disassembled form; and (3) after the step of transporting through the pre-existing elevator shaft, assembling the gantry system on the ground floor, the step of assembling comprising attaching the first circular segment of the main bearing to the second circular segment of the main bearing using the intermediate section.
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公开(公告)号：US10279198B2
公开(公告)日：2019-05-07
申请号：US15868966
申请日：2018-01-11
摘要： A scintillation material is longitudinally packaged in a circumferentially surrounding sheath, where the sheath has a lower index of refraction than the scintillation material, to form a scintillation optic or scintillation fiber optic. The scintillation material yields secondary photons upon passage of a charged particle beam, such as a positively charged residual particle beam having transmitted through a sample. The internally generated secondary photons within the sheath are guided to a detector element by the difference in index of refraction. Multiple scintillation optics are assembled to form a two-dimensional scintillation array coupled to a two-dimensional detector array, such as for use in determination of state of the residual charged particle beam, determination of an exit point of the particle beam from the sample, path of the treatment beam, and/or tomographic imaging.
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公开(公告)号：US10070831B2
公开(公告)日：2018-09-11
申请号：US15182507
申请日：2016-06-14
CPC分类号： A61B6/4085 , A61B6/032 , A61B6/4014 , A61B6/4258 , A61B6/487 , A61B6/5205 , A61N5/1044 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1061 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要： The invention comprises a positively charged particle based cancer therapy system integrated with at least one off-axis imaging system, where elements of the off-axis imaging system and the cancer therapy system are co-positioned/co-rotated with a gantry. The imaging apparatus optionally functions with a tomography system using the positively charged particles of the cancer therapy system for enhanced patient/tumor imaging at and/or prior to a time of treatment.
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公开(公告)号：US20180133512A1
公开(公告)日：2018-05-17
申请号：US15868966
申请日：2018-01-11
CPC分类号： A61N5/1069 , A61B6/03 , A61B6/032 , A61B6/0457 , A61B6/4014 , A61B6/4092 , A61B6/4258 , A61B6/4266 , A61B6/4417 , A61B6/4435 , A61B6/5205 , A61B6/5247 , A61N5/1037 , A61N5/1039 , A61N5/1067 , A61N5/107 , A61N5/1077 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1061 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G01N23/046 , G01N2223/107 , G01N2223/203 , G21K1/093 , G21K5/04
摘要： A scintillation material is longitudinally packaged in a circumferentially surrounding sheath, where the sheath has a lower index of refraction than the scintillation material, to form a scintillation optic or scintillation fiber optic. The scintillation material yields secondary photons upon passage of a charged particle beam, such as a positively charged residual particle beam having transmitted through a sample. The internally generated secondary photons within the sheath are guided to a detector element by the difference in index of refraction. Multiple scintillation optics are assembled to form a two-dimensional scintillation array coupled to a two-dimensional detector array, such as for use in determination of state of the residual charged particle beam, determination of an exit point of the particle beam from the sample, path of the treatment beam, and/or tomographic imaging.
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公开(公告)号：US20160354616A1
公开(公告)日：2016-12-08
申请号：US15239773
申请日：2016-08-17
IPC分类号： A61N5/10
CPC分类号： A61N5/1069 , A61B6/03 , A61B6/032 , A61B6/0457 , A61B6/4014 , A61B6/4092 , A61B6/4258 , A61B6/4266 , A61B6/4417 , A61B6/4435 , A61B6/5205 , A61B6/5247 , A61N5/1037 , A61N5/1039 , A61N5/1067 , A61N5/107 , A61N5/1077 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1061 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G01N23/046 , G01N2223/107 , G01N2223/203 , G21K1/093 , G21K5/04
摘要： A scintillation material is longitudinally packaged in a circumferentially surrounding sheath, where the sheath has a lower index of refraction than the scintillation material, to form a scintillation optic or scintillation fiber optic. The scintillation material yields secondary photons upon passage of a charged particle beam, such as a positively charged residual particle beam having transmitted through a sample. The internally generated secondary photons within the sheath are guided to a detector element by the difference in index of refraction. Multiple scintillation optics are assembled to form a two-dimensional scintillation array coupled to a two-dimensional detector array, such as for use in determination of state of the residual charged particle beam, determination of an exit point of the particle beam from the sample, path of the treatment beam, and/or tomographic imaging.
摘要翻译： 闪烁材料纵向包装在周向环绕的护套中，其中护套具有比闪烁材料更低的折射率，以形成闪烁光学或闪烁光纤。 闪烁材料在带电粒子束通过时产生次级光子，例如透过样品的带正电荷的残余粒子束。 鞘内的内部产生的次级光子被折射率的差引导到检测器元件。 组合多个闪烁光学器件以形成耦合到二维检测器阵列的二维闪烁阵列，例如用于确定残留带电粒子束的状态，确定来自样品的粒子束的出口点， 治疗束的路径和/或层析成像。
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7.发明申请公开(公告)号：US20160287908A1
公开(公告)日：2016-10-06
申请号：US15182507
申请日：2016-06-14
CPC分类号： A61B6/4085 , A61B6/032 , A61B6/4014 , A61B6/4258 , A61B6/487 , A61B6/5205 , A61N5/1044 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1061 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要： The invention comprises a positively charged particle based cancer therapy system integrated with at least one off-axis imaging system, where elements of the off-axis imaging system and the cancer therapy system are co-positioned/co-rotated with a gantry. The imaging apparatus optionally functions with a tomography system using the positively charged particles of the cancer therapy system for enhanced patient/tumor imaging at and/or prior to a time of treatment.
摘要翻译： 本发明包括与至少一个离轴成像系统集成的带正电粒子的癌症治疗系统，其中离轴成像系统的元件和癌症治疗系统与台架共同定位/共转动。 成像设备可选地与使用癌症治疗系统的带正电颗粒的断层摄影系统一起起作用，以在治疗时和/或之前进行增强的患者/肿瘤成像。
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公开(公告)号：US09974978B2
公开(公告)日：2018-05-22
申请号：US15239773
申请日：2016-08-17
CPC分类号： A61N5/1069 , A61B6/03 , A61B6/032 , A61B6/0457 , A61B6/4014 , A61B6/4092 , A61B6/4258 , A61B6/4266 , A61B6/4417 , A61B6/4435 , A61B6/5205 , A61B6/5247 , A61N5/1037 , A61N5/1039 , A61N5/1067 , A61N5/107 , A61N5/1077 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1061 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G01N23/046 , G01N2223/107 , G01N2223/203 , G21K1/093 , G21K5/04
摘要： A scintillation material is longitudinally packaged in a circumferentially surrounding sheath, where the sheath has a lower index of refraction than the scintillation material, to form a scintillation optic or scintillation fiber optic. The scintillation material yields secondary photons upon passage of a charged particle beam, such as a positively charged residual particle beam having transmitted through a sample. The internally generated secondary photons within the sheath are guided to a detector element by the difference in index of refraction. Multiple scintillation optics are assembled to form a two-dimensional scintillation array coupled to a two-dimensional detector array, such as for use in determination of state of the residual charged particle beam, determination of an exit point of the particle beam from the sample, path of the treatment beam, and/or tomographic imaging.
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公开(公告)号：US09910166B2
公开(公告)日：2018-03-06
申请号：US15170744
申请日：2016-06-01
CPC分类号： G01T1/20 , A61B6/032 , A61B6/4258 , A61B6/5205 , A61N5/1044 , A61N5/1049 , A61N5/1067 , A61N5/107 , A61N5/1082 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要： The invention comprises a system for redundantly determining the state of a charged particle beam, such as beam position, direction, energy, and/or intensity. For example, the charged particle beam state is determined: (1) in an extraction system from a synchrotron, (2) in a charged particle beam transport path, and/or (3) at or about a patient undergoing charged particle cancer therapy using one or more film layers designed to emit photons upon passage of a charged particle beam, which yields information on position and/or intensity of the charged particle beam. The emitted photons are used to calculate position, direction, and/or intensity of the treatment beam in imaging and/or during tumor treatment.
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10.发明申请CHARGED PARTICLE - PATIENT MOTION CONTROL SYSTEM APPARATUS AND METHOD OF USE THEREOF 审中-公开充电颗粒 - 患者运动控制系统装置及其使用方法公开(公告)号：US20160287907A1
公开(公告)日：2016-10-06
申请号：US15176025
申请日：2016-06-07
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61B6/032 , A61B6/4258 , A61B6/5205 , A61N5/1044 , A61N5/1067 , A61N5/107 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要： The invention comprises a system for controlling a charged particle beam shape and direction relative to a controlled and dynamically positioned patient and/or an imaging surface, such as a scintillation plate of a tomography system and/or a first two-dimensional imaging system coupled to a second two-dimensional imaging system. Multiple interlinked beam/patient/imaging control stations allow safe zone operation and clear interaction with the charged particle beam system and the patient. Both treatment and imaging are facilitated using automated sequences controlled with a work-flow control system.
摘要翻译： 本发明包括一种用于控制带电粒子束形状和相对于被控和动态定位的患者和/或成像表面的方向的系统，诸如层析成像系统的闪烁板和/或第一二维成像系统 第二个二维成像系统。 多个相互连接的束/患者/成像控制站允许安全区域操作和与带电粒子束系统和患者的清晰的相互作用。 使用通过工作流控制系统控制的自动化序列便于治疗和成像。
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