公开(公告)号：US20220395611A1

公开(公告)日：2022-12-15

申请号：US17774875

申请日：2020-12-18

申请人： Spiderwort Inc. ,  University of Ottawa

发明人： Maxime LEBLANC LATOUR ,  Ryan HICKEY ,  Charles M. CUERRIER ,  Andrew E. PELLING ,  Maryam TARAR ,  Isabelle CATELAS

IPC分类号： A61L27/36 ,  A61L27/52 ,  A61L27/24 ,  A61L27/20 ,  A61L27/38 ,  A61L27/12 ,  A61L27/04 ,  A61L27/10

摘要： Provided herein are scaffold biomaterials including a decellularized plant or fungal tissue from which cellular materials and nucleic acids of the tissue are removed, the decellularized plant or fungal tissue having a 3-dimensional porous structure; wherein the decellularized plant or fungal tissue may optionally be at least partially coated or mineralized, wherein the scaffold biomaterial may optionally further include a protein-based hydrogel and/or a polysaccharide-based hydrogel, or both. Also provided herein are methods and uses of such scaffold biomaterials, including methods of manufacture as well as methods and uses for bone tissue engineering, for example.