Use of lipid conjugates in the treatment of diseases or disorders of the eye
    2.
    发明申请
    Use of lipid conjugates in the treatment of diseases or disorders of the eye 有权
    使用脂质偶联物治疗眼睛疾病或病症

    公开(公告)号:US20080113935A1

    公开(公告)日:2008-05-15

    申请号:US11984223

    申请日:2007-11-14

    摘要: In one embodiment, the invention provides a method of treating, reducing the incidence, reducing the severity or pathogenesis of an eye disease or disorder in a subject, including, inter alia, retinal detachment, macular degeneration, glaucoma or retinopathy, comprising the step of administering an effective amount of a lipid or phospholipid moiety bound optionally via a spacer to a physiologically acceptable monomer, dimer, oligomer, or polymer via an ester or amide bond, and/or a pharmaceutically acceptable salt or a pharmaceutical product thereof. This invention also provides a contact lens solution comprising a lipid or phospholipid moiety bound optionally via a spacer to a physiologically acceptable monomer, dimer, oligomer, or polymer via an ester or amide bond, and/or a pharmaceutically acceptable salt or a pharmaceutical product thereof.

    摘要翻译: 在一个实施方案中,本发明提供了治疗,降低发病率,降低受试者眼睛疾病或病症的严重性或发病机理的方法,包括尤其是视网膜脱离,黄斑变性,青光眼或视网膜病变,包括以下步骤: 通过酯或酰胺键将有效量的任选地通过间隔基连接到生理上可接受的单体,二聚体,低聚物或聚合物的脂质或磷脂部分,和/或其药学上可接受的盐或药物产品。 本发明还提供一种隐形眼镜溶液,其包含通过间隔基任选地通过酯或酰胺键与生理学上可接受的单体,二聚体,低聚物或聚合物结合的脂质或磷脂部分和/或其药学上可接受的盐或其药物产物 。

    Use of lipid conjugates in the treatment of diseases or disorders of the eye
    4.
    发明授权
    Use of lipid conjugates in the treatment of diseases or disorders of the eye 有权
    使用脂质偶联物治疗眼睛疾病或病症

    公开(公告)号:US08865681B2

    公开(公告)日:2014-10-21

    申请号:US11984223

    申请日:2007-11-14

    摘要: In one embodiment, the invention provides a method of treating, reducing the incidence, reducing the severity or pathogenesis of an eye disease or disorder in a subject, including, inter alia, retinal detachment, macular degeneration, glaucoma or retinopathy, comprising the step of administering an effective amount of a lipid or phospholipid moiety bound optionally via a spacer to a physiologically acceptable monomer, dimer, oligomer, or polymer via an ester or amide bond, and/or a pharmaceutically acceptable salt or a pharmaceutical product thereof. This invention also provides a contact lens solution comprising a lipid or phospholipid moiety bound optionally via a spacer to a physiologically acceptable monomer, dimer, oligomer, or polymer via an ester or amide bond, and/or a pharmaceutically acceptable salt or a pharmaceutical product thereof.

    摘要翻译: 在一个实施方案中,本发明提供了治疗,降低发病率,降低受试者眼睛疾病或病症的严重性或发病机理的方法,包括尤其是视网膜脱离,黄斑变性,青光眼或视网膜病变,包括以下步骤: 通过酯或酰胺键将有效量的任选地通过间隔基连接到生理上可接受的单体,二聚体,低聚物或聚合物的脂质或磷脂部分,和/或其药学上可接受的盐或药物产品。 本发明还提供一种隐形眼镜溶液,其包含通过间隔基任选地通过酯或酰胺键与生理学上可接受的单体,二聚体,低聚物或聚合物结合的脂质或磷脂部分和/或其药学上可接受的盐或其药物产物 。

    SYSTEM AND METHOD FOR DETERMINING A TOPOLOGY OF AT LEAST ONE APPLICATION IN A COMPUTERIZED ORGANIZATION
    5.
    发明申请
    SYSTEM AND METHOD FOR DETERMINING A TOPOLOGY OF AT LEAST ONE APPLICATION IN A COMPUTERIZED ORGANIZATION 有权
    用于确定计算机组织中至少一个应用的拓扑的系统和方法

    公开(公告)号:US20130332590A1

    公开(公告)日:2013-12-12

    申请号:US13816142

    申请日:2011-08-09

    IPC分类号: H04L29/08

    摘要: A computerized method for determining a structure of at least one application in a computerized organization, the method comprising receiving at least one entry point including an identification of a virtual location on a computer network; for each entry point, receiving a determination of an individual applicative component that processes data arriving through that entry point; identifying at least some communicating entry points through which the first applicative component communicates with additional applicative components; and for each of the at least some communicating entry points, using a processor for determining the applicative component that processes data arriving through that communicating entry point; and providing at least a portion of a structure including: applicative components associated with the application and information with regard to which of the applicative component communicates with which.

    摘要翻译: 一种用于确定计算机化组织中的至少一个应用的结构的计算机化方法,所述方法包括:在计算机网络上接收包括虚拟位置的标识的至少一个入口点; 对于每个入口点,接收处理通过该入口点到达的数据的单独应用组件的确定; 识别至少一些通信入口点,第一应用组件通过该入口点与附加的应用组件通信; 并且对于所述至少一些通信入口点中的每一个,使用处理器来确定处理通过所述通信入口点到达的数据的应用组件; 以及提供结构的至少一部分,其包括:与所述应用相关联的应用组件和关于应用组件中的哪一个与哪个应用相关联的信息。

    SYSTEM AND METHOD FOR STORING A SKELETON REPRESENTATION OF AN APPLICATION IN A COMPUTERIZED ORGANIZATION
    6.
    发明申请
    SYSTEM AND METHOD FOR STORING A SKELETON REPRESENTATION OF AN APPLICATION IN A COMPUTERIZED ORGANIZATION 有权
    用于存储计算机组织中应用程序的表示的系统和方法

    公开(公告)号:US20130325899A1

    公开(公告)日:2013-12-05

    申请号:US13816133

    申请日:2011-08-09

    IPC分类号: G06F17/30

    摘要: A computerized method for storing a representation of at least one application in a computerized organization, the method comprising determining a structure of at least one application in a computerized organization; and using a processor for generating, and storing, a skeleton characterization of the structure of the application including storing information, characterizing at least one applicative component identified, that is considered stable over time and not storing information, characterizing at least one applicative component identified, that is considered unstable over time.

    摘要翻译: 一种用于在计算机化组织中存储至少一个应用的表示的计算机化方法,所述方法包括确定计算机化组织中的至少一个应用的结构; 以及使用处理器来生成和存储所述应用的结构的骨架表征,包括存储信息,表征所识别的至少一个应用组件,所述至少一个应用组件随着时间而被认为是稳定的,而不存储信息,其特征在于,识别的至少一个应用组件, 这被认为是不稳定的。

    System and method for optimization of three-dimensional audio

    公开(公告)号:US07123731B2

    公开(公告)日:2006-10-17

    申请号:US10220969

    申请日:2001-03-07

    IPC分类号: H04R5/02

    CPC分类号: H04S7/301 H04S7/302

    摘要: The invention provides a system for optimization of three-dimensional audio listening having a media player and a multiplicity of speakers disposed within a listening space, the system including a portable sensor having a multiplicity of transducers strategically arranged about the sensor for receiving test signals from the speakers and for transmitting the signals to a processor connectable in the system for receiving multi-channel audio signals from the media player and for transmitting the multi-channel audio signals to the multiplicity of speakers, the processor including (a) means for initiating transmission of test signals to each of the speakers and for receiving the test signals from the speakers to be processed for determining the location of each of the speakers relative to a listening place within the space determined by the placement of the sensor; (b) means for manipulating each sound track of the multi-channel sound signals with respect to intensity, phase and/or equalization according to the relative location of each speaker in order to create virtual sound sources in desired positions, and (c) means for communicating between the sensor and the processor. The invention further provides a method for the optimization of three-dimensional audio listening using the above-described system.

    Apparatus and methods for individual addressing and noise reduction in actuator arrays

    公开(公告)号:US09425708B2

    公开(公告)日:2016-08-23

    申请号:US13989979

    申请日:2011-11-17

    摘要: Apparatus for generating a target physical effect, at least one attribute of which corresponds to at least one characteristic of a digital input signal sampled periodically, the apparatus comprising a multiplicity of electrostatic actuator elements, each comprising a moving element moving between first and second electrodes, the multiplicity of electrostatic actuator elements including Nr first subsets (R-subsets) of actuator elements and Nc second subsets (C-subsets) of actuator elements, wherein a first partitioning of the multiplicity of actuator elements yields the Nr first subsets (R-subsets) and a second partitioning of the multiplicity of actuator elements yields the Nc second subsets (C-subsets); a first plurality of Nr electrical connections (R-wires) interconnecting the moving elements of actuator elements in each R-subset, such that the moving element of any actuator element in each individual R-subset is electrically connected to the moving elements of all other actuator elements in the individual R-subset, and electrically isolated from the moving elements of all actuator elements not in the individual R-subset; a second plurality of Nc electrical connections (A-wires) interconnecting the first electrodes of actuator elements in each C-subset, such that the first electrode of any actuator element in each individual C-subset is electrically connected to the first electrode of all other actuator elements in the individual C-subset, and electrically isolated from all actuator elements not in the individual C-subset; a third plurality of Nc electrical connections (B-wires) interconnecting the second electrodes of actuator elements in each C-subset, such that the second electrode of any actuator element in each individual C-subset is electrically connected to the second electrode of all other actuator elements in the individual C-subset, and electrically isolated from all actuator elements not in the individual C-subset; and a controller electrically connected to the first, second and third pluralities of electrical connections, operative to receive a digital input signal, and to apply one of a predetermined, finite set of electric potentials to each of said electrical connections respectively, such that resulting movements of the moving elements together produce the desired physical effect.

    Method and apparatus for managing packets in a packet switched network
    10.
    发明授权
    Method and apparatus for managing packets in a packet switched network 有权
    用于在分组交换网络中管理分组的方法和装置

    公开(公告)号:US08923297B1

    公开(公告)日:2014-12-30

    申请号:US13415557

    申请日:2012-03-08

    IPC分类号: H04L12/28

    摘要: Methods and apparatus for managing packets in a packet switched network include, in at least one aspect, a device including: an input to receive a packet from one of a plurality of network devices, the plurality of network devices configured to communicate with one or more others of the network devices using a plurality of packets; and circuitry configured to control packet switching of the plurality of packets, at least one packet including: a switch tag including a tag portion embedded with switching information and an extended tag portion embedded with additional switching information, the switching information and the additional switching information configured to control a switching pattern associated with the at least one packet.

    摘要翻译: 在分组交换网络中用于管理分组的方法和装置在至少一个方面包括:设备,包括:用于从多个网络设备之一接收分组的输入,所述多个网络设备被配置为与一个或多个 使用多个分组的其他网络设备; 以及电路,被配置为控制所述多个分组的分组交换,所述至少一个分组包括:包括嵌入有交换信息的标签部分的交换标签和嵌入​​有附加切换信息的扩展标签部分,所述切换信息和所述附加切换信息被配置 以控制与所述至少一个分组相关联的切换模式。