公开(公告)号：US11834686B2

公开(公告)日：2023-12-05

申请号：US16545363

申请日：2019-08-20

申请人： Sangamo Therapeutics, Inc.

发明人： Friedrich Fauser ,  Jeffrey C. Miller ,  Edward Rebar

IPC分类号： C12N9/22 ,  C12N9/78 ,  C12N15/11 ,  C12N15/63

CPC分类号： C12N9/22 ,  C12N9/78 ,  C12N15/11 ,  C12N15/63 ,  C12Y305/04001 ,  C12Y305/04002 ,  C12N2310/20 ,  C12N2310/3181 ,  C12N2310/323 ,  C12N2310/3231 ,  C12N2800/80

摘要： Described herein are DNA-editing complexes, particularly DNA-editing complexes that specifically alter a single base pair in target DNA sequence as well as methods of making and using these DNA-editing complexes.

公开(公告)号：US20200063114A1

公开(公告)日：2020-02-27

申请号：US16545363

申请日：2019-08-20

申请人： Sangamo Therapeutics, Inc.

发明人： Friedrich Fauser ,  Jeffrey C. Miller ,  Edward Rebar

IPC分类号： C12N9/22 ,  C12N9/78 ,  C12N15/11 ,  C12N15/63

摘要： Described herein are DNA-editing complexes, particularly DNA-editing complexes that specifically alter a single base pair in target DNA sequence as well as methods of making and using these DNA-editing complexes.