专利检索 ap:("Sanford-Burnham Medical Research Institute") AND inv:"Michael R. JACKSON" 第 1 页

1.

发明申请
Pyrazolopyrimidines as Inhibitors of Glucocorticoid Receptor Translocation 审中-公开

公开(公告)号：US20180207140A1

公开(公告)日：2018-07-26

申请号：US15546165

申请日：2016-01-28

申请人： Sanford-Burnham Medical Research Institute

发明人： Anthony B. PINKERTON , Christian A. HASSIG , Michael R. JACKSON , Robert John ARDECKY , Ian PASS

IPC分类号： A61K31/437 , A61P35/00

CPC分类号： A61K31/437 , A61K45/06 , A61P35/00 , C07D471/04 , A61K2300/00

摘要： Provided herein are compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of Glucocorticoid Receptor (GR) translocation. Furthermore, the subject compounds and compositions are useful for the treatment of diseases involved in the hypothalamic-pituitary-adrenal (HPA) axis.