公开(公告)号：US20170046478A1

公开(公告)日：2017-02-16

申请号：US15159546

申请日：2016-05-19

Applicant: Samsung Electronics Co., Ltd.

Inventor： Garima AGARWAL ,  Srikanth Rama MALLAVARAPU ,  Ajit Shyamsunder BOPARDIKAR ,  Taejin AHN

IPC: G06F19/22 ,  G06N5/02 ,  G06F19/00 ,  G06F17/30

Abstract: Provided are methods and devices for mutation prioritization, which are helpful in personalized therapy of a patient. Also, provided are methods and devices for generating a disease knowledgebase. Information present in various categories of knowledge sources with respect to a particular association of set may be identified. The identified information is ranked with respect to the disease knowledgebase to find out the most relevant ones for the treatment of a particular Disease/Gene/Mutation of a patient, thereby enabling medical experts to personalize a therapy to be administered to a patient.

Abstract translation: 提供了用于突变优先化的方法和装置，其有助于患者的个性化治疗。 此外，提供了用于产生疾病知识库的方法和装置。 可以确定在各种知识来源中存在关于<疾病，基因，突变>集合的特定关联的信息。 所识别的信息相对于疾病知识库进行排名，以找出用于治疗患者的特定疾病/基因/突变的最相关的信息，从而使医学专家能够个性化要施用于患者的治疗。