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公开(公告)号：US09902776B2
公开(公告)日：2018-02-27
申请号：US14446167
申请日：2014-07-29
Applicant: Samsung Electronics Co., Ltd.
Inventor： Mi Young Cho , Seung Hyun Lee , Kwang Ho Cheong , Young Jun Koh , Jung Wook Lee , Powei Lin , Jae Woong Hwang
IPC: C07K16/28 , A61K39/395 , A61K39/00
CPC classification number: C07K16/2863 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/52 , C07K2317/565 , C07K2317/622 , C07K2317/624 , C07K2317/73 , C07K2317/92 , C07K2319/00
Abstract: An anti-EGFR scFV fragment, an anti-c-Met/anti-EGFR bispecific antibody including the same, and a method of preventing and/or treating a cancer using the same are provided.
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公开(公告)号：US10000569B2
公开(公告)日：2018-06-19
申请号：US14692934
申请日：2015-04-22
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kwang Ho Cheong , Jae Woong Hwang , Seung Hyun Lee , Powei Lin , Mi Young Cho
CPC classification number: C07K16/2863 , A61K39/395 , A61K39/39558 , A61K2039/505 , A61K2039/507 , C07K16/32 , C07K16/40 , C07K2317/31 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C12N15/09
Abstract: An anti-EGFR/anti-HER3 antibody or antigen binding fragment thereof, and a method of preventing and/or treating a cancer using the same.
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公开(公告)号：US09956244B2
公开(公告)日：2018-05-01
申请号：US14814278
申请日：2015-07-30
Applicant: Samsung Electronics Co., Ltd.
Inventor： Ji Min Lee , Bo Gyou Kim , Seung Ja Oh , Kyung Ah Kim , Saet Byoul Lee , Jae Woong Hwang
IPC: G01N33/50 , G01N33/574 , A61K31/713 , C07K16/28 , A61K39/395 , A61K45/06 , C07K16/30
CPC classification number: A61K31/713 , A61K39/39533 , A61K39/39558 , A61K45/06 , C07K16/2863 , C07K16/30 , C07K2317/24 , C07K2317/31 , C07K2317/52 , C07K2317/54 , C07K2317/565 , C07K2317/622 , C07K2317/76 , C07K2317/92 , G01N33/57484 , G01N2800/52 , A61K2300/00 , A61K31/573
Abstract: A biomarker Hsp90 for predicting an efficacy of a c-Met inhibitor, selecting a subject for application of a c-Met inhibitor, or monitoring an efficacy of a c-Met inhibitor, and a relevant method of using Hsp90.
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4.发明申请ANTI-CMET/ANTI-EGFR/ANTI-HER3 MULTIPECIFIC ANTIBODIES AND USE THEREOF 有权抗CMET /抗EGFR /抗-IV3多种抗体及其用途公开(公告)号：US20150322165A1
公开(公告)日：2015-11-12
申请号：US14692934
申请日：2015-04-22
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kwang Ho Cheong , Jae Woong Hwang , Seung Hyun Lee , Powei Lin , Mi Young Cho
CPC classification number: C07K16/2863 , A61K39/395 , A61K39/39558 , A61K2039/505 , A61K2039/507 , C07K16/32 , C07K16/40 , C07K2317/31 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C12N15/09
Abstract: An anti-EGFR/anti-HER3 antibody or antigen binding fragment thereof, and a method of preventing and/or treating a cancer using the same
Abstract translation: 抗EGFR /抗HER3抗体或其抗原结合片段，以及使用其的预防和/或治疗癌症的方法
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5.发明申请ANTI-EGFR/ANTI-HER2 BISPECIFIC ANTIBODIES WITH ANTI-EGFR DARPINS 有权抗EGFR /抗HER2抗双抗体与抗EGFR DARPINS抗体公开(公告)号：US20150232573A1
公开(公告)日：2015-08-20
申请号：US14625296
申请日：2015-02-18
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kwang Ho Cheong , Seung Hyun Lee , Powei Lin , Saet Byoul Lee , Jae Woong Hwang
CPC classification number: C07K16/2863 , C07K16/32 , C07K2317/31 , C07K2317/73 , C07K2317/77 , C07K2317/92
Abstract: An anti-EGFR/anti-HER2 bispecific antibody including an anti-EGFR DARPin and an anti-HER2 antibody, a pharmaceutical composition including the bispecific antibody, a method of preparing the bispecific antibody, and a method of reducing a side effect and/or enhancing efficacy of an anti-HER2 antibody using an anti-EGFR DARPin.
Abstract translation: 包含抗EGFR DARPin和抗HER2抗体的抗EGFR /抗HER2双特异性抗体，包含双特异性抗体的药物组合物，制备双特异性抗体的方法和减少副作用的方法和/或 使用抗EGFR DARPin增强抗HER2抗体的功效。
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Patent Agency Ranking
公开(公告)号：US20150030596A1
公开(公告)日：2015-01-29
申请号：US14444632
申请日：2014-07-28
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kwang Ho CHEONG , Young Jun Koh , Min-Kyung Kim , Powei Lin , Seung Hyun Lee , Jung Wook Lee , Mi Young Cho , Jae Woong Hwang
IPC: C07K16/28 , C07K14/705
CPC classification number: C07K16/2863 , C07K14/705 , C07K16/32 , C07K2317/24 , C07K2317/31 , C07K2317/53 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2318/20 , C07K2319/30 , C07K2319/33
Abstract: A bispecific chimeric protein including a designed ankyrin repeat protein (DARPin), and an IgG antibody, an scFv-Fc antibody fragment, or a combination thereof, linked to the DARPin; a method for treating or preventing cancer using the same; and related methods and compositions.
Abstract translation: 包含与DARPin连接的双特异性嵌合蛋白，包括设计的锚蛋白重复蛋白（DARPin）和IgG抗体，scFv-Fc抗体片段或其组合; 使用该方法治疗或预防癌症的方法; 以及相关方法和组成。
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公开(公告)号：US09359440B2
公开(公告)日：2016-06-07
申请号：US14444632
申请日：2014-07-28
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kwang Ho Cheong , Young Jun Koh , Min-Kyung Kim , Powei Lin , Seung Hyun Lee , Jung Wook Lee , Mi Young Cho , Jae Woong Hwang
IPC: C07K16/28 , C07K16/32 , C07K14/705
CPC classification number: C07K16/2863 , C07K14/705 , C07K16/32 , C07K2317/24 , C07K2317/31 , C07K2317/53 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2318/20 , C07K2319/30 , C07K2319/33
Abstract: A bispecific chimeric protein including a designed ankyrin repeat protein (DARPin), and an IgG antibody, an scFv-Fc antibody fragment, or a combination thereof, linked to the DARPin; a method for treating or preventing cancer using the same; and related methods and compositions.
Abstract translation: 包含与DARPin连接的双特异性嵌合蛋白，包括设计的锚蛋白重复蛋白（DARPin）和IgG抗体，scFv-Fc抗体片段或其组合; 使用该方法治疗或预防癌症的方法; 以及相关方法和组成。
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公开(公告)号：US09975960B2
公开(公告)日：2018-05-22
申请号：US14709214
申请日：2015-05-11
Applicant: Samsung Electronics Co., Ltd.
Inventor： Mi Young Cho , Powei Lin , Kwang Ho Cheong , Jae Woong Hwang , Geun Woong Kim , Han Na Choi
CPC classification number: C07K16/32 , A61K39/395 , A61K39/39533 , A61K39/39558 , A61K2039/507 , C07K16/2863 , C07K16/40 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/77 , C07K2317/92
Abstract: An anti-HER2 antibody, an anti-c-Met/anti-HER2 bispecific antibody including the same, method for preparing same, and a method of preventing and/or treating a cancer using the same are provided.
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9.发明申请ANTI-EGFR ANTIBODY AND ANTI-C-MET/ANTI-EGFR BISPECIFIC ANTIBODIES COMPRISING THE SAME 有权抗EGFR抗体和抗C-MET /抗EGFR抗体相似抗体公开(公告)号：US20150030599A1
公开(公告)日：2015-01-29
申请号：US14446167
申请日：2014-07-29
Applicant: Samsung Electronics Co., Ltd.
Inventor： Mi Young CHO , Seung Hyun Lee , Kwang Ho Cheong , Young Jun Koh , Jung Wook Lee , Powei Lin , Jae Woong Hwang
IPC: C07K16/28
CPC classification number: C07K16/2863 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/52 , C07K2317/565 , C07K2317/622 , C07K2317/624 , C07K2317/73 , C07K2317/92 , C07K2319/00
Abstract: An anti-EGFR scFV fragment, an anti-c-Met/anti-EGFR bispecific antibody including the same, and a method of preventing and/or treating a cancer using the same are provided.
Abstract translation: 提供抗EGFR scFV片段，包含其的抗c-Met /抗EGFR双特异性抗体，以及使用其的预防和/或治疗癌症的方法。
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公开(公告)号：US10143749B2
公开(公告)日：2018-12-04
申请号：US14229308
申请日：2014-03-28
Applicant: Samsung Electronics Co., Ltd.
Inventor： Mi Young Cho , Powei Lin , Seung Hyun Lee , Kwang Ho Cheong , Young Jun Koh , Christina Yi , Jae Woong Hwang
IPC: C07K16/30 , C07K16/46 , A61K39/395 , C07K16/28 , C07K16/32
Abstract: There are provided an anti-c-Met/anti-Her2 bispecific antibody, and a method for preventing and/or treating cancer using the same.
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