公开(公告)号：US20160178490A1

公开(公告)日：2016-06-23

申请号：US14976043

申请日：2015-12-21

Applicant: Saint-Gobain Performance Plastics Corporation

Inventor： Edouard Civel ,  Sarah Louise Clark ,  Herbert Myers Cullis ,  Natasha Anna Lundgren ,  Jeffrey Ellis Miripol ,  Camila A. Garces

IPC: G01N1/40

CPC classification number: C12M47/04 ,  C08F259/08 ,  C08J7/18 ,  G01N33/543 ,  G01N33/54353 ,  C08F220/06

Abstract: Embodiments of the disclosure include systems and methods for capturing particular biological matter from a sample from an individual. The systems and methods employ an apparatus (such as a container that is a tube or bag) comprising a fluoropolymer coating that is modified to comprise one or more moieties for binding of a desired biological agents when a sample is exposed to the modified fluoropolymer. In particular aspects, the biological matter is a particular type of cell, such as a particular blood or bone marrow cell, and the desired cell is captured by means of an aptamer selected to bind the cell.

Abstract translation: 本公开的实施方案包括用于从个体的样品捕获特定生物物质的系统和方法。 该系统和方法采用包含含氟聚合物涂层的装置（例如管或袋的容器），当将样品暴露于改性含氟聚合物时，该含氟聚合物涂层被修饰成包含一个或多个用于结合所需生物制剂的部分。 在特定方面，生物物质是特定类型的细胞，例如特定的血液或骨髓细胞，并且所需细胞通过选择用于结合细胞的适体捕获。

公开(公告)号：US12037570B2

公开(公告)日：2024-07-16

申请号：US16404681

申请日：2019-05-06

Applicant: Saint-Gobain Performance Plastics Corporation

Inventor： Natasha Anna Lundgren ,  Sarah Louise Clark ,  Edouard Civel ,  Jeffrey Ellis Miripol ,  Herbert Myers Cullis ,  Phillippe Jean Broussard

IPC: C12M1/04 ,  C12M1/00 ,  C12M1/12

CPC classification number: C12M23/24 ,  C12M23/26 ,  C12M25/02 ,  C12M29/04 ,  C12M29/26

Abstract: A cell culture container is provided, comprising membrane bound compartments for growing and harvesting monocytes that allows replenishing and removal of feed media without the loss or death of cells.

公开(公告)号：US20160178491A1

公开(公告)日：2016-06-23

申请号：US14976071

申请日：2015-12-21

Applicant: Saint-Gobain Performance Plastics Corporation

Inventor： Edouard Civel ,  Sarah Louise Clark ,  Herbert Myers Cullis ,  Natasha Anna Lundgren ,  Jeffrey Ellis Miripol ,  Camila A. Garces

IPC: G01N1/40

CPC classification number: G01N33/54393

Abstract: Embodiments of the disclosure include systems and methods for capturing particular biological matter from a sample from an individual. The systems and methods employ an apparatus (such as a container that is a tube or bag) comprising a fluoropolymer coating that is modified to comprise one or more moieties for binding of a desired biological agents when a sample is exposed to the modified fluoropolymer. In particular aspects, the biological matter is a particular type of cell, such as a particular blood or bone marrow cell, and the desired cell is captured by means of an aptamer selected to bind the cell.

公开(公告)号：US10280390B2

公开(公告)日：2019-05-07

申请号：US14976091

申请日：2015-12-21

Applicant: Saint-Gobain Performance Plastics Corporation

Inventor： Natasha Anna Lundgren ,  Sarah Louise Clark ,  Edouard Civel ,  Jeffrey Ellis Miripol ,  Herbert Myers Cullis ,  Phillippe Jean Broussard

IPC: C12M1/04 ,  C12M1/00 ,  C12M1/12

Abstract: A cell culture container is provided, comprising membrane bound compartments for growing and harvesting monocytes that allows replenishing and removal of feed media without the loss or death of cells.

公开(公告)号：US20160177246A1

公开(公告)日：2016-06-23

申请号：US14976091

申请日：2015-12-21

Applicant: Saint-Gobain Performance Plastics Corporation

Inventor： Natasha Anna Lundgren ,  Sarah Louise Clark ,  Edouard Civel ,  Jeffrey Ellis Miripol ,  Herbert Myers Cullis ,  Phillippe Jean Broussard

IPC: C12M1/04 ,  C12M1/12

CPC classification number: C12M23/24 ,  C12M25/02 ,  C12M29/04

Abstract: A cell culture container is provided, comprising membrane bound compartments for growing and harvesting monocytes that allows replenishing and removal of feed media without the loss or death of cells.

Abstract translation: 提供了一种细胞培养容器，其包括用于生长和收获单核细胞的膜结合室，其允许补充和除去饲料培养基，而不会导致细胞的损失或死亡。