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    Device and means of assessing neuromuscular junction status with higher fidelity
    1.
    发明授权
    Device and means of assessing neuromuscular junction status with higher fidelity 有权

    公开(公告)号：US11510603B2

    公开(公告)日：2022-11-29

    申请号：US17127445

    申请日：2020-12-18

    申请人： SafeOp Surgical, Inc.

    发明人： Robert Snow ,  Richard O'Brien

    IPC分类号： A61B5/24 ,  A61B5/00 ,  A61B5/389

    摘要： Devices and methods for stimulation and recording of muscle responses for determining degree of neuromuscular blockade, particularly relevant to elicitation of such responses in those under the influence of anesthesia. A system for estimating the degree of neuromuscular blockade includes at least one stimulating electrode, at least one recording electrode, a pulse generator for providing stimulation to a nerve through the stimulating electrode, and a computing device configured to: apply stimuli to the nerve according to a stimulation protocol, wherein the stimulation protocol provides a plurality of stimulation sequences that vary in frequency of pulses in the stimulation sequence, frequency of the stimulation sequences, number of pulses in the stimulation sequence, or all of the above; measure, by the recording electrode, electrical responses of a muscle; and estimate the degree of neuromuscular blockade based on changes in the electrical responses of the muscle during a stimulation sequence.

    SYSTEMS AND METHODS FOR PLACEMENT OF SPINAL CORD STIMULATOR LEADS
    2.
    发明申请
    SYSTEMS AND METHODS FOR PLACEMENT OF SPINAL CORD STIMULATOR LEADS 审中-公开

    公开(公告)号：US20190275333A1

    公开(公告)日：2019-09-12

    申请号：US16348437

    申请日：2017-11-13

    申请人： SafeOp Surgical, Inc.

    发明人： Richard O'Brien

    IPC分类号： A61N1/36 ,  A61B5/04 ,  A61B5/00 ,  A61N1/05

    摘要： A method of optimally placing spinal cord stimulator (SCS) leads includes acquiring components of somatosensory evoked potentials (SSEPs), compound action potentials and triggered EMG; analyzing the waveforms; and quantifying waveform features in a single display such that a surgeon can quickly and easily determine optimal placement (as it relates to laterality and level of placement on the spinal cord) of SCS leads in a patient under general anesthesia without additional expert help.

    A DEVICE AND MEANS OF ASSESSING NEUROMUSCULAR JUNCTION STATUS WITH HIGHER FIDELITY
    5.
    发明申请
    A DEVICE AND MEANS OF ASSESSING NEUROMUSCULAR JUNCTION STATUS WITH HIGHER FIDELITY 审中-公开

    公开(公告)号：US20180333569A1

    公开(公告)日：2018-11-22

    申请号：US15529928

    申请日：2015-11-25

    申请人： SafeOp Surgical, Inc.

    发明人： Robert Snow ,  Richard O'Brien

    IPC分类号： A61N1/02 ,  G16H20/40

    CPC分类号： A61N1/02 ,  A61B5/04001 ,  A61B5/0488 ,  A61B5/4821 ,  A61B5/4839 ,  A61B2505/05 ,  G16H20/40

    摘要： Devices and methods for stimulation and recording of muscle responses for determining degree of neuromuscular blockade, particularly relevant to elicitation of such responses in those under the influence of anesthesia. A system for estimating the degree of neuromuscular blockade includes at least one stimulating electrode, at least one recording electrode, a pulse generator for providing stimulation to a nerve through the stimulating electrode, and a computing device configured to: apply stimuli to the nerve according to a stimulation protocol, wherein the stimulation protocol provides a plurality of stimulation sequences that vary in frequency of pulses in the stimulation sequence, frequency of the stimulation sequences, number of pulses in the stimulation sequence, or all of the above; measure, by the recording electrode, electrical responses of a muscle; and estimate the degree of neuromuscular blockade based on changes in the electrical responses of the muscle during a stimulation sequence.

    System, method, and computer algorithm for measuring, displaying, and accurately detecting changes in electrophysiological evoked potentials
    6.
    发明授权
    System, method, and computer algorithm for measuring, displaying, and accurately detecting changes in electrophysiological evoked potentials 有权

    公开(公告)号：US11197640B2

    公开(公告)日：2021-12-14

    申请号：US15569367

    申请日：2016-05-03

    申请人： SafeOp Surgical, Inc.

    发明人： Gregg Johns ,  Richard O'Brien ,  Robert Snow

    IPC分类号： A61B5/377 ,  A61B5/00 ,  A61B5/24 ,  G16H50/50 ,  A61G13/06

    摘要： An automated evoked potential analysis apparatus for improved monitoring, detecting and identifying changes to a patient's physiological system is described. The apparatus includes an input device for obtaining electrical potential data from the patient's physiological system after application of stimulation to a patient's nerve and a computing system for receiving and analyzing the electrical potential data. The computing system includes a processing circuit configured to: generate a plurality of evoked potential waveforms (EPs) based on the electrical potential data, measure changes or trends in the generated EPs utilizing a sliding window of analysis, display incremental changes in waveforms between full subsets of EPs, and determine an alert vote for each subset, representative of changes to the physiological system generating the EPs.

    DEVICE AND MEANS OF ASSESSING NEUROMUSCULAR JUNCTION STATUS WITH HIGHER FIDELITY
    7.
    发明申请
    DEVICE AND MEANS OF ASSESSING NEUROMUSCULAR JUNCTION STATUS WITH HIGHER FIDELITY 有权

    公开(公告)号：US20210100490A1

    公开(公告)日：2021-04-08

    申请号：US17127445

    申请日：2020-12-18

    申请人： SafeOp Surgical, Inc.

    发明人： Robert Snow ,  Richard O'Brien

    IPC分类号： A61B5/24 ,  A61B5/00 ,  A61B5/389

    摘要： Devices and methods for stimulation and recording of muscle responses for determining degree of neuromuscular blockade, particularly relevant to elicitation of such responses in those under the influence of anesthesia. A system for estimating the degree of neuromuscular blockade includes at least one stimulating electrode, at least one recording electrode, a pulse generator for providing stimulation to a nerve through the stimulating electrode, and a computing device configured to: apply stimuli to the nerve according to a stimulation protocol, wherein the stimulation protocol provides a plurality of stimulation sequences that vary in frequency of pulses in the stimulation sequence, frequency of the stimulation sequences, number of pulses in the stimulation sequence, or all of the above; measure, by the recording electrode, electrical responses of a muscle; and estimate the degree of neuromuscular blockade based on changes in the electrical responses of the muscle during a stimulation sequence.

    SYSTEM, METHOD, AND COMPUTER ALGORITHM FOR MEASURING, DISPLAYING, AND ACCURATELY DETECTING CHANGES IN ELECTROPHYSIOLOGICAL EVOKED POTENTIALS
    10.
    发明申请
    SYSTEM, METHOD, AND COMPUTER ALGORITHM FOR MEASURING, DISPLAYING, AND ACCURATELY DETECTING CHANGES IN ELECTROPHYSIOLOGICAL EVOKED POTENTIALS 有权

    公开(公告)号：US20220096022A1

    公开(公告)日：2022-03-31

    申请号：US17549764

    申请日：2021-12-13

    申请人： SafeOp Surgical, Inc.

    发明人： Gregg Johns ,  Richard O'Brien ,  Robert Snow

    IPC分类号： A61B5/00 ,  A61B5/24 ,  A61B5/377 ,  G16H50/50 ,  A61G13/06

    摘要： An automated evoked potential analysis apparatus for improved monitoring, detecting and identifying changes to a patient's physiological system is described. The apparatus includes an input device for obtaining electrical potential data from the patient's physiological system after application of stimulation to a patient's nerve and a computing system for receiving and analyzing the electrical potential data. The computing system includes a processing circuit configured to: generate a plurality of evoked potential waveforms (EPs) based on the electrical potential data, measure changes or trends in the generated EPs utilizing a sliding window of analysis, display incremental changes in waveforms between full subsets of EPs, and determine an alert vote for each subset, representative of changes to the physiological system generating the EPs.