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    System, method, and computer algorithm for measuring, displaying, and accurately detecting changes in electrophysiological evoked potentials
    2.
    发明授权
    System, method, and computer algorithm for measuring, displaying, and accurately detecting changes in electrophysiological evoked potentials 有权

    公开(公告)号：US11197640B2

    公开(公告)日：2021-12-14

    申请号：US15569367

    申请日：2016-05-03

    申请人： SafeOp Surgical, Inc.

    发明人： Gregg Johns ,  Richard O'Brien ,  Robert Snow

    IPC分类号： A61B5/377 ,  A61B5/00 ,  A61B5/24 ,  G16H50/50 ,  A61G13/06

    摘要： An automated evoked potential analysis apparatus for improved monitoring, detecting and identifying changes to a patient's physiological system is described. The apparatus includes an input device for obtaining electrical potential data from the patient's physiological system after application of stimulation to a patient's nerve and a computing system for receiving and analyzing the electrical potential data. The computing system includes a processing circuit configured to: generate a plurality of evoked potential waveforms (EPs) based on the electrical potential data, measure changes or trends in the generated EPs utilizing a sliding window of analysis, display incremental changes in waveforms between full subsets of EPs, and determine an alert vote for each subset, representative of changes to the physiological system generating the EPs.

    MEDICAL SYSTEMS AND METHODS FOR DETECTING CHANGES IN ELECTROPHYSIOLOGICAL EVOKED POTENTIALS
    3.
    发明申请
    MEDICAL SYSTEMS AND METHODS FOR DETECTING CHANGES IN ELECTROPHYSIOLOGICAL EVOKED POTENTIALS 审中-公开

    公开(公告)号：US20180310849A1

    公开(公告)日：2018-11-01

    申请号：US15927921

    申请日：2018-03-21

    申请人： SafeOp Surgical, Inc.

    发明人： Gregg Johns ,  Richard Arthur O'Brien ,  Robert Snow

    IPC分类号： A61B5/04 ,  A61B5/00

    CPC分类号： A61B5/00 ,  A61B5/04

    摘要： A medical method of automatically improving signals received from a patient's physiological system can include delivering stimulation signals to a nerve pathway of a patient with electrical pulses via electrodes placed over the nerve pathway to generate a plurality of resultant electrical waveforms (EPs) based on a plurality of electrophysiological responses (ERs); recording the plurality of resultant EPs; generating an ensemble average waveform (EA), the generating comprising averaging a subset of the plurality of ERs; and denoising the EA, the denoising comprising applying a wavelet transform to the EA.

    SYSTEM, METHOD, AND COMPUTER ALGORITHM FOR MEASURING, DISPLAYING, AND ACCURATELY DETECTING CHANGES IN ELECTROPHYSIOLOGICAL EVOKED POTENTIALS
    8.
    发明申请
    SYSTEM, METHOD, AND COMPUTER ALGORITHM FOR MEASURING, DISPLAYING, AND ACCURATELY DETECTING CHANGES IN ELECTROPHYSIOLOGICAL EVOKED POTENTIALS 有权

    公开(公告)号：US20220096022A1

    公开(公告)日：2022-03-31

    申请号：US17549764

    申请日：2021-12-13

    申请人： SafeOp Surgical, Inc.

    发明人： Gregg Johns ,  Richard O'Brien ,  Robert Snow

    IPC分类号： A61B5/00 ,  A61B5/24 ,  A61B5/377 ,  G16H50/50 ,  A61G13/06

    摘要： An automated evoked potential analysis apparatus for improved monitoring, detecting and identifying changes to a patient's physiological system is described. The apparatus includes an input device for obtaining electrical potential data from the patient's physiological system after application of stimulation to a patient's nerve and a computing system for receiving and analyzing the electrical potential data. The computing system includes a processing circuit configured to: generate a plurality of evoked potential waveforms (EPs) based on the electrical potential data, measure changes or trends in the generated EPs utilizing a sliding window of analysis, display incremental changes in waveforms between full subsets of EPs, and determine an alert vote for each subset, representative of changes to the physiological system generating the EPs.

    SYSTEMS, METHODS, AND DEVICES FOR DETECTING THE THRESHOLD OF NERVE-MUSCLE RESPONSE USING VARIABLE FREQUENCY OF STIMULATION
    9.
    发明申请
    SYSTEMS, METHODS, AND DEVICES FOR DETECTING THE THRESHOLD OF NERVE-MUSCLE RESPONSE USING VARIABLE FREQUENCY OF STIMULATION 审中-公开

    公开(公告)号：US20180360336A1

    公开(公告)日：2018-12-20

    申请号：US16010157

    申请日：2018-06-15

    申请人： SafeOp Surgical, Inc. ,  Alphatec Spine, Inc.

    发明人： Richard A. O'Brien ,  Gregg Johns ,  Robert Snow ,  James E. Gharib

    IPC分类号： A61B5/04 ,  A61B5/0488 ,  A61B5/00 ,  G16H20/30

    摘要： A method for determining a lowest stimulation threshold current level in a group of channels of a neuromonitoring device. The method includes stimulating tissue at a current level from a predetermined range of current levels as a sequence of pulses delivered at a frequency. The stimulating includes increasing the current level of each pulse in the sequence of pulses from an immediately preceding pulse by a first current increment. The method includes determining that a first evocation pulse from the sequence of pulses evokes a first muscular response. The method includes stimulating the tissue with a second evocation pulse from the sequence of pulses to evoke a second muscular response. The stimulating includes decreasing the frequency of the delivery of each pulse in the sequence of pulses and increasing the current level of each pulse in the sequence of pulses from the immediately preceding pulse by a second current increment. The method includes determining that the second evocation pulse from the sequence of pulses evokes the second muscular response.