公开(公告)号：US09765032B2

公开(公告)日：2017-09-19

申请号：US15117058

申请日：2014-12-26

Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED

Inventor： Tadafumi Matsunaga ,  Natsuru Hiraguri ,  Tomoaki Takahashi ,  Tomohiko Inui ,  Masaya Tanimoto

IPC: C07D231/10 ,  C07D231/12 ,  C07D231/16 ,  C07C209/88 ,  C07C211/60 ,  C07B57/00

CPC classification number: C07D231/10 ,  C07B57/00 ,  C07B2200/07 ,  C07C209/84 ,  C07C209/88 ,  C07C211/60 ,  C07C2602/08 ,  C07D231/12 ,  C07D231/14 ,  C07D231/16

Abstract: A method for producing (R)-1,1,3-trimethyl-4-aminoindane includes the following steps (A), (B), and (C). Step (A) is a step of optically resolving 1,1,3-trimethyl-4-aminoindane to obtain (R)-1,1,3-trimethyl-4-aminoindane and (S)-1,1,3-trimethyl-4-aminoindane, step (B) is a step of racemizing the (S)-1,1,3-trimethyl-4-aminoindane obtained in the step (A) or (C) to obtain 1,1,3-trimethyl-4-aminoindane, and step (C) is a step of optically resolving the 1,1,3-trimethyl-4-aminoindane obtained in the step (B) to obtain (R)-1,1,3-trimethyl-4-aminoindane and (S)-1,1,3-trimethyl-4-aminoindane.

公开(公告)号：US10562885B2

公开(公告)日：2020-02-18

申请号：US16490950

申请日：2018-02-21

Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED

Inventor： Tomohiko Inui ,  Masaya Tanimoto

IPC: C07D401/14 ,  C07D471/04

Abstract: A compound represented by formula (5) can be produced by simultaneously and separately adding a compound represented by formula (4) and methanesulfonyl chloride to a compound represented by formula (3) and a compound represented by formula (6) having excellent control efficacies against pests can be produced by subjecting the compound represented by formula (5) to intramolecular condensation in the presence of an acid.

公开(公告)号：US20150203438A1

公开(公告)日：2015-07-23

申请号：US14418872

申请日：2013-08-28

Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED

Inventor： Satoru Ujita ,  Tsutomu Matsumoto ,  Tomohiko Inui

IPC: C07C209/88 ,  C07C211/60 ,  C07C59/255 ,  C07C51/41

CPC classification number: C07C209/88 ,  C07B57/00 ,  C07C51/412 ,  C07C59/255 ,  C07C211/60 ,  C07C2602/08

Abstract: A method for producing a methanol solvate of D-tartrate of (R)-1,1,3-trimethyl-4-aminoindane, the method comprising steps (a), (b), and (c) below, and comprising adding water to a reaction system before step (c): step (a) of mixing 1,1,3-trimethyl-4-aminoindane, D-tartaric acid, and methanol to provide a mixture containing a methanol solvate of D-tartrate of (R)-1,1,3-trimethyl-4-aminoindane; step (b) of cooling the obtained mixture; and step (c) of retrieving the methanol solvate of D-tartrate of (R)-1,1,3-trimethyl-4-aminoindane.

Abstract translation: （R）-1,1,3-三甲基-4-氨基茚满的D-酒石酸盐的甲醇溶剂合物的制造方法，其特征在于，包括下述（a），（b），（c）的方法， 在步骤（c）之前的反应体系中：步骤（a）将1,1,3-三甲基-4-氨基茚满，D-酒石酸和甲醇混合，得到含有（R ）-1,1,3-三甲基-4-氨基茚满; 步骤（b）冷却所得混合物; 和（R）-1,1,3-三甲基-4-氨基茚满D-酒石酸盐的甲醇溶剂化物的步骤（c）。

公开(公告)号：US09227911B2

公开(公告)日：2016-01-05

申请号：US14418872

申请日：2013-08-28

Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED

Inventor： Satoru Ujita ,  Tsutomu Matsumoto ,  Tomohiko Inui

IPC: C07C209/88 ,  C07C51/41 ,  C07C59/255 ,  C07C211/60 ,  C07B57/00 ,  C07C57/00

CPC classification number: C07C209/88 ,  C07B57/00 ,  C07C51/412 ,  C07C59/255 ,  C07C211/60 ,  C07C2602/08

Abstract: A method for producing a methanol solvate of D-tartrate of (R)-1,1,3-trimethyl-4-aminoindane, the method comprising steps (a), (b), and (c) below, and comprising adding water to a reaction system before step (c): step (a) of mixing 1,1,3-trimethyl-4-aminoindane, D-tartaric acid, and methanol to provide a mixture containing a methanol solvate of D-tartrate of (R)-1,1,3-trimethyl-4-aminoindane; step (b) of cooling the obtained mixture; and step (c) of retrieving the methanol solvate of D-tartrate of (R)-1,1,3-trimethyl-4-aminoindane.

Abstract translation: （R）-1,1,3-三甲基-4-氨基茚满的D-酒石酸盐的甲醇溶剂合物的制造方法，其特征在于，包括下述（a），（b），（c）的方法， 在步骤（c）之前的反应体系中：步骤（a）将1,1,3-三甲基-4-氨基茚满，D-酒石酸和甲醇混合，得到含有（R ）-1,1,3-三甲基-4-氨基茚满; 步骤（b）冷却所得混合物; 和（R）-1,1,3-三甲基-4-氨基茚满D-酒石酸盐的甲醇溶剂化物的步骤（c）。