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公开(公告)号：US09173692B1
公开(公告)日：2015-11-03
申请号：US13918949
申请日：2013-06-15
申请人： STC.UNM
发明人： Paul E. Kaloostian
CPC分类号： A61B17/864 , A61B17/68 , A61B17/7002 , A61B17/702 , A61B17/7035 , A61B17/7037 , A61B17/7098 , A61B17/80 , A61B17/8605 , A61B17/8615 , A61B17/8625 , A61B17/866 , A61B17/8685 , A61B17/8841 , A61B2017/00933 , A61B2017/00964 , A61F2/44 , A61F2002/2835 , A61F2002/30405 , A61F2002/3055 , A61F2002/30601 , A61F2002/30784 , A61F2002/30787 , A61F2310/00023 , A61F2310/00359 , A61F2310/00958 , A61F2310/0097
摘要： Composite orthopedic devices that facilitate spine stabilization, such as: bone screws, rods, plates, interbodies, and corpectomy cages are disclosed. They are designed to provide both strength and load carrying capabilities, while increasing bio-integration of the devices with the surrounding bone tissue. They are constructed of composite layers of allograft and/or autograft bone and a structural material, such as titanium alloy or carbon/graphite fiber composite. Cannulations within the device are loaded with a mixture of stem cells, particles of allograft and/or autograft bone, and bone growth factors, such as BMP-2. The cannulations are connected to the surface of the device via multiple fenestrations that provide pathways to supply the bone/stem cell mixture to the surface, allowing living bone tissue to grow and insure bio-integration. The devices can also have radiofrequency (RF) stimulation implantation within the structure of the implanted device, capable of responding to external RF stimulation of enhanced bone growth.
摘要翻译： 公开了促进脊柱稳定的复合矫形装置，例如：骨螺钉，杆，板，中间体和椎骨切除术笼。 它们旨在提供强度和负载能力，同时增加设备与周围骨组织的生物整合。 它们由同种异体移植物和/或自体骨的复合层和诸如钛合金或碳/石墨纤维复合材料的结构材料构成。 装置内的装置装载有干细胞，同种异体移植物和/或自体骨的颗粒和骨生长因子如BMP-2的混合物。 插管通过多个窗口连接到装置的表面，这些开窗提供将骨/干细胞混合物提供给表面的途径，允许活骨组织生长并确保生物整合。 该装置还可以在植入装置的结构内具有射频（RF）刺激植入，能够响应增强的骨生长的外部RF刺激。
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公开(公告)号：US20160000489A1
公开(公告)日：2016-01-07
申请号：US14854387
申请日：2015-09-15
申请人： STC.UNM
发明人： Paul E. Kaloostian
CPC分类号： A61B17/864 , A61B17/68 , A61B17/7002 , A61B17/702 , A61B17/7035 , A61B17/7037 , A61B17/7098 , A61B17/80 , A61B17/8605 , A61B17/8615 , A61B17/8625 , A61B17/866 , A61B17/8685 , A61B17/8841 , A61B2017/00933 , A61B2017/00964 , A61F2/44 , A61F2002/2835 , A61F2002/30405 , A61F2002/3055 , A61F2002/30601 , A61F2002/30784 , A61F2002/30787 , A61F2310/00023 , A61F2310/00359 , A61F2310/00958 , A61F2310/0097
摘要： Composite orthopedic devices that facilitate spine stabilization, such as: bone screws, rods, plates, interbodies, and corpectomy cages are disclosed. They are designed to provide both strength and load carrying capabilities, while increasing bio-integration of the devices with the surrounding bone tissue. They are constructed of composite layers of allograft and/or autograft bone and a structural material, such as titanium alloy or carbon/graphite fiber composite. Cannulations within the device are loaded with a mixture of stem cells, particles of allograft and/or autograft bone, and bone growth factors, such as BMP-2. The cannulations are connected to the surface of the device via multiple fenestrations that provide pathways to supply the bone/stem cell mixture to the surface, allowing living bone tissue to grow and insure bio-integration. The devices can also have radiofrequency (RF) stimulation implantation within the structure of the implanted device, capable of responding to external RF stimulation of enhanced bone growth.
摘要翻译： 公开了促进脊柱稳定的复合矫形装置，例如：骨螺钉，杆，板，中间体和椎骨切除术笼。 它们旨在提供强度和负载能力，同时增加设备与周围骨组织的生物整合。 它们由同种异体移植和/或自体骨的复合层和诸如钛合金或碳/石墨纤维复合材料的结构材料构成。 装置内的装置装载有干细胞，同种异体移植物和/或自体骨的颗粒和骨生长因子如BMP-2的混合物。 插管通过多个窗口连接到装置的表面，这些开窗提供将骨/干细胞混合物提供给表面的途径，允许活骨组织生长并确保生物整合。 该装置还可以在植入装置的结构内具有射频（RF）刺激植入，能够响应增强的骨生长的外部RF刺激。
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