公开(公告)号：US20220287920A1

公开(公告)日：2022-09-15

申请号：US17201165

申请日：2021-03-15

申请人： SHOFU INC.

发明人： Kenzo YAMAMOTO ,  Daisuke HARA ,  Shunsuke MIYATA

IPC分类号： A61K6/62 ,  A61K6/887

摘要： To provide a dental photocurable composition which can exhibit excellent mechanical characteristics even after returning from a low temperature to room temperature.
To provide a dental photocurable composition, comprising (A) polymerizable monomer, (B) photosensitizer, (C) photoacid generator and (D) photopolymerization accelerator and the (C) photoacid generator may include only (C-1) iodonium salt-based compound of an anion having log S of −4 or less.

公开(公告)号：US20200214819A1

公开(公告)日：2020-07-09

申请号：US16575867

申请日：2019-09-19

申请人： SHOFU INC.

发明人： Daisuke HARA ,  Naoya KITADA ,  Kenzo YAMAMOTO ,  Yasuhiro NISHINO ,  Yoshiyuki JOGETSU

IPC分类号： A61C19/10

摘要： [Problem]To select a dental cement or a trial test material for easily obtaining high color tone adaptability to peripheral tooth substances, in mounting of or trial test of a prosthesis device[Solution]To provide a dental cement set consisting of a plurality of dental cements having color tones including color tones of 3 to n colors for selecting and using a dental cement from the plurality of dental cements having the color tones including the color tones of the 3 to n colors after trial test with trial test materials for the dental cement to be used from the plurality of dental cements having the color tones including the color tones of the 3 to n colors, wherein: the amount of information loss Pin with regard to first principal component determined by principal component analysis is less than 2, and . the dental cement set satisfies following Formula 1. 2≤((CL*p−1−CL*p)2 +(Ca*p−1−Ca*p)2 +(Cb*p−1−Cb*p)2)1/2

公开(公告)号：US20220387263A1

公开(公告)日：2022-12-08

申请号：US17692584

申请日：2022-03-11

申请人： SHOFU INC.

发明人： Naoya KITADA ,  Rei NISHIMURA ,  Daisuke HARA ,  Kenzo YAMAMOTO

IPC分类号： A61K6/896 ,  A61K6/62 ,  A61K6/76 ,  A61K6/17

摘要： To provide a dental photocurable composition having good storage stability of a matrix containing a polymerizable monomer and a polymerization initiator, etc. and excellent mechanical strength of a dental photocurable composition comprising a mixture of the matrix and a filler. The dental photocurable composition of the present disclosure comprises a matrix containing (A) polymerizable monomer, (B) photosensitizer, (C) photoacid generator and (D) photopolymerization accelerator, and (E) filler, wherein, the dental photocurable composition comprises (A1) polymerizable monomer having an acidic group as the (A) polymerizable monomer, and the dental photocurable composition comprises (D1) tertiary aliphatic amine compound having Log P of 2 or more and pKa of 10 or less as the (D) photopolymerization accelerator.

公开(公告)号：US20210189098A1

公开(公告)日：2021-06-24

申请号：US17032284

申请日：2020-09-25

申请人： SHOFU INC.

发明人： Daisuke HARA ,  Kenzo YAMAMOTO ,  Yasuhiro NISHINO ,  Kazuya SHINNO

IPC分类号： C08K5/00 ,  C08F220/12 ,  C08K9/06 ,  C08K3/40 ,  C08K5/1575 ,  C08K9/02 ,  C08K3/16 ,  C08K3/11 ,  C08K3/22 ,  C08K3/30 ,  C08K3/36 ,  C08L33/12

摘要： To provide a dental curable composition having excellent curability and storage stability. The dental curable composition contains(a) transition metal adsorbent in which a transition metal compound of the period 4 in the periodic table is adsorbed on an inorganic particle which is non-reactive with a transition metal of the period 4 in the periodic table, (b) thiourea derivative, (c) organic peroxide having a hydroperoxide group, and (d) polymerizable monomer, wherein the (d) polymerizable monomer contains (d-1) acidic group-non-containing polymerizable monomer, and wherein a pore volume of the inorganic particle which is non-reactive with a transition metal of the period 4 in the periodic table is 0.2 cc/g or less.

公开(公告)号：US20220401312A1

公开(公告)日：2022-12-22

申请号：US17692568

申请日：2022-03-11

申请人： SHOFU INC.

发明人： Kenzo YAMAMOTO ,  Hideto KASABA ,  Daisuke HARA ,  Shunsuke MIYATA

IPC分类号： A61K6/896 ,  A61C5/00 ,  A61K6/76 ,  A61K6/62

摘要： [Problem]
To provide a dental photocurable composition which has sufficient mechanical property and whose rheological property is not deactivated even after long-term storage.
[Solution]
The dental photocurable composition of the present disclosure comprises (A) polymerizable monomer, (B) photosensitizer, (D) photopolymerization accelerator and (E) filler, wherein, the dental photocurable composition comprises (D1) aliphatic tertiary amine compound represented by formula (1) as the (D) photopolymerization accelerator, and the dental photocurable composition comprises (E1) hydrophobized silica fine particle having an average diameter of primary particle of 1 to 40 nm as the (E) filler. (wherein R1 represents a substituent consisting of three or more carbons having an electron-withdrawing group at α-carbon and/or ε-carbon of an amine starting from N, R2 represents a substituent consisting of three or more carbons which may have an electron-withdrawing group, R3 represents a substituent consisting of one or more carbons which may have an electron-withdrawing group, and α-carbon of N in the formula (1) is not an electron-withdrawing group.)

公开(公告)号：US20150342838A1

公开(公告)日：2015-12-03

申请号：US14593103

申请日：2015-01-09

申请人： SHOFU INC.

发明人： Daisuke HARA ,  Yuji SADAKANE ,  Katsura ISHIKAWA ,  Hidefumi FUJIMURA ,  Shuji SAKAMOTO ,  Akihiro NAGAFUJI ,  Toshiyuki NAKATSUKA

IPC分类号： A61K6/00 ,  A61Q11/00 ,  A61K8/19 ,  A61K8/21 ,  A61K8/25 ,  A61K8/26

摘要： To provide a dental composition wherein the acid buffering capacity can be attained and the acid resistance of the tooth substance can be improved while maintaining very high foul breath inhibition capacity. A dental composition including: ion sustained-release glass; and a carrier for supporting the ion sustained-release glass, wherein the ion sustained-release glass is fluoroaluminoborosilicate glass having a composition range of: 15% to 35% by mass SiO2; 15% to 30% by mass Al2O3; 5% to 20% by mass B2O3; 20% to 45% by mass SrO; 5% to 15% by mass F; and 0% to 10% by mass Na2O.

摘要翻译： 提供一种可以获得酸缓冲能力并且可以在保持非常高的防臭呼吸抑制能力的同时提高牙齿物质的耐酸性的牙科用组合物。 一种牙科用组合物，包括：离子缓释玻璃; 以及用于支撑所述离子缓释玻璃的载体，其中所述离子缓释玻璃是组成范围为15〜35质量％SiO 2的氟铝白玻璃; 15〜30质量％的Al2O3; 5〜20质量％B2O3; 20〜45质量％的SrO; 5〜15质量％F; 和0〜10质量％的Na 2 O。

公开(公告)号：US20230255857A1

公开(公告)日：2023-08-17

申请号：US18130664

申请日：2023-04-04

申请人： SHOFU INC.

发明人： Daisuke HARA ,  Yuji SADAKANE ,  Katsura ISHIKAWA ,  Hidefumi FUJIMURA ,  Shuji SAKAMOTO ,  Akihiro NAGAFUJI ,  Toshiyuki NAKATSUKA

IPC分类号： A61K6/70 ,  A61K8/25 ,  A61K8/26 ,  A61K8/19 ,  A61K8/21 ,  A61Q11/00 ,  A61K8/81 ,  A61K6/20 ,  A61K6/77

CPC分类号： A61K6/70 ,  A61K8/25 ,  A61K8/26 ,  A61K8/19 ,  A61K8/21 ,  A61Q11/00 ,  A61K8/8152 ,  A61K6/20 ,  A61K6/77 ,  A61K2800/56 ,  A61K2800/81 ,  A61K2800/882 ,  A61K2800/95

摘要： To provide a dental composition wherein the acid buffering capacity can be attained and the acid resistance of the tooth substance can be improved while maintaining very high foul breath inhibition capacity. A dental composition including: ion sustained-release glass; and a carrier for supporting the ion sustained-release glass, wherein the ion sustained-release glass is fluoroaluminoborosilicate glass having a composition range of: 15% to 35% by mass SiO2; 15% to 30% by mass Al2O3; 5% to 20% by mass B2O3; 20% to 45% by mass SrO; 5% to 15% by mass F; and 0% to 10% by mass Na2O.

公开(公告)号：US20220387264A1

公开(公告)日：2022-12-08

申请号：US17692598

申请日：2022-03-11

申请人： SHOFU INC.

发明人： Shunsuke MIYATA ,  Kenzo YAMAMOTO ,  Daisuke HARA

IPC分类号： A61K6/896 ,  A61K6/62 ,  A61K6/71 ,  A61K6/77 ,  A61K6/76

摘要： [Problem]
To provide a dental curable composition having good mechanical property and good storage stability before and after curing.
Solution
The dental curable composition of the present disclosure comprises (A) polymerizable monomer, (BC) polymerization initiator, (D) polymerization accelerator and (E) filler, wherein, the (BC) polymerization initiator comprises (B) photopolymerization initiator and/or (C) chemical polymerization initiator, the (B) photopolymerization initiator comprises (B1) photosensitizer and (B2) photoacid generator, the (C) chemical polymerization initiator comprises (C1) organic peroxide, the (E) filler comprises (E1) surface-treated basic filler, and the (E1) surface-treated basic filler is treated with (F1) surface treatment agent represented by the formula (1) and/or condensate thereof. [Formula (1)] MXn  [Chemical formula 1] (In the formula, M is a metal atom selected from Si, Ti, Zr, and Al, X is H, OH or a hydrolyzable group, and may be the same or different from each other. In the case that M is Si, Ti or Zr, n is 4. In the case that M is Al, n is 3.)

公开(公告)号：US20220287921A1

公开(公告)日：2022-09-15

申请号：US17201180

申请日：2021-03-15

申请人： SHOFU INC.

发明人： Kenzo YAMAMOTO ,  Hideto KASABA ,  Daisuke HARA ,  Shunsuke MIYATA

IPC分类号： A61K6/62 ,  A61K6/71 ,  A61K6/78

摘要： [Problem]
To provide a dental photocurable composition having sufficient mechanical property and being excellent in color tone selectivity because of having a small color difference between before curing and after curing.
[Solution]
To provide a dental photocurable composition, comprising (A) polymerizable monomer, (B) photosensitizer, (C) photoacid generator, (D) photopolymerization accelerator and (E) filler, wherein, the dental photocurable composition comprises (B-1) α-diketone compound as the (B) photosensitizer, and the dental photocurable composition comprises, with respect to 100 parts by mass of the (A) polymerizable monomer, 0.15 parts by mass or less of the (B-1) α-diketone compound, 0.5 parts by mass or more of the (C) photoacid generator, and 100 parts by mass or more of the (E) filler.

公开(公告)号：US20180344579A1

公开(公告)日：2018-12-06

申请号：US16059446

申请日：2018-08-09

申请人： SHOFU INC.

发明人： Daisuke HARA ,  Yuji SADAKANE ,  Katsura ISHIKAWA ,  Hidefumi FUJIMURA ,  Shuji SAKAMOTO ,  Akihiro NAGAFUJI ,  Toshiyuki NAKATSUKA

IPC分类号： A61K6/00 ,  A61K8/26 ,  A61Q11/00 ,  A61K8/21 ,  A61K8/19 ,  A61K8/25 ,  A61K8/81 ,  C08L33/06

CPC分类号： A61K6/007 ,  A61K6/0017 ,  A61K6/0091 ,  A61K8/19 ,  A61K8/21 ,  A61K8/25 ,  A61K8/26 ,  A61K8/8152 ,  A61K2800/56 ,  A61K2800/81 ,  A61K2800/882 ,  A61K2800/95 ,  A61Q11/00 ,  C08L33/06

摘要： To provide a dental composition wherein the acid buffering capacity can be attained and the acid resistance of the tooth substance can be improved while maintaining very high foul breath inhibition capacity. A dental composition including: ion sustained-release glass; and a carrier for supporting the ion sustained-release glass, wherein the ion sustained-release glass is fluoroaluminoborosilicate glass having a composition range of: 15% to 35% by mass SiO2; 15% to 30% by mass Al2O3; 5% to 20% by mass B2O3; 20% to 45% by mass SrO; 5% to 15% by mass F; and 0% to 10% by mass Na2O.