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    SMALL MOLECULE POLYPEPTIDE FOR PREVENTING AND RESTRAINING INFLAMMATION AND APPLICATION OF SAME
    4.
    发明申请
    SMALL MOLECULE POLYPEPTIDE FOR PREVENTING AND RESTRAINING INFLAMMATION AND APPLICATION OF SAME 有权
    用于预防和限制其相容性和应用的小分子聚合物

    公开(公告)号：US20150266926A1

    公开(公告)日：2015-09-24

    申请号：US14412497

    申请日：2011-12-19

    申请人： Xun Xu ,  Yan Xu

    发明人： Xun Xu ,  Yan Xu

    IPC分类号： C07K14/00

    CPC分类号： C07K14/001 ,  A61K38/00 ,  C07K14/4705

    摘要： The present invention provides a polypeptide that is rich in leucine and used for preventing and restraining inflammation, and an application of same. The present invention further provides a method for preparing the polypeptide and a pharmaceutical composition containing the polypeptide. The advantage of the polypeptide comprises: small molecular weight, so as to permeate various eye tissue barriers; high water solubility, so as to have high dissolubility in neutral tears, aqueous humor and vitreous humor; and simple synthesis, so as to have a low preparation cost.

    摘要翻译： 本发明提供富含亮氨酸并用于预防和抑制炎症的多肽及其应用。 本发明还提供了制备多肽的方法和含有多肽的药物组合物。 多肽的优点包括：分子量小，以渗透各种眼组织屏障; 水溶性高，以至于在中性眼泪，房水和玻璃体液中具有高溶解性; 和简单的合成，从而具有较低的制备成本。

    Small molecule polypeptide for inhibiting inflammation
    5.
    发明授权
    Small molecule polypeptide for inhibiting inflammation 有权

    公开(公告)号：US09688726B2

    公开(公告)日：2017-06-27

    申请号：US14412497

    申请日：2011-12-19

    申请人： Xun Xu ,  Yan Xu

    发明人： Xun Xu ,  Yan Xu

    IPC分类号： C07K14/00 ,  C07K14/47 ,  A61K38/00

    CPC分类号： C07K14/001 ,  A61K38/00 ,  C07K14/4705

    摘要： The present invention provides a polypeptide that is rich in leucine and used for preventing and restraining inflammation, and an application of same. The present invention further provides a method for preparing the polypeptide and a pharmaceutical composition containing the polypeptide. The advantage of the polypeptide comprises: small molecular weight, so as to permeate various eye tissue barriers; high water solubility, so as to have high dissolubility in neutral tears, aqueous humor and vitreous humor; and simple synthesis, so as to have a low preparation cost.

    SINGLE CELL CLASSIFICATION METHOD, GENE SCREENING METHOD AND DEVICE THEREOF
    6.
    发明申请
    SINGLE CELL CLASSIFICATION METHOD, GENE SCREENING METHOD AND DEVICE THEREOF 审中-公开
    单细胞分类方法，基因筛选方法及其装置

    公开(公告)号：US20140206006A1

    公开(公告)日：2014-07-24

    申请号：US14239650

    申请日：2012-08-24

    申请人： Xun Xu ,  Li Bao ,  Weiming He ,  Yong Hou ,  Ye Tao

    发明人： Xun Xu ,  Li Bao ,  Weiming He ,  Yong Hou ,  Ye Tao

    IPC分类号： G06F19/22

    CPC分类号： G16B30/00 ,  C12Q1/6827 ,  C12Q1/6869 ,  G16B20/00

    摘要： Provided are a single cell classification method, a gene screening method and a device for implementing the method. In that, the single cell classification method includes the following steps: sequencing the whole genomes of a plurality of single cell samples from the same group, respectively, so as to obtain reads from each single cell sample; aligning the reads from each single cell sample to the sequence of a reference genome, respectively, and performing data filtering on said reads; on the basis of the filtered reads, determining a consistent genotype of each single cell sample, in which consistent genotypes of all the single cell samples constitute an SNP dataset of said group; aimed at said each single cell, on the basis of the SNP dataset of said group, determining a corresponding genotype for each cell at a site corresponding to a position in an SNP dataset of the reference genome; and selecting an SNP site associated with cell mutation, and on the basis of the genotype of said single cell at the site, classifying said single cell.

    摘要翻译： 提供单细胞分类方法，基因筛选方法和实施该方法的装置。 其中，单细胞分类方法包括以下步骤：从同一组分别测序多个单细胞样品的全基因组，从而获得每个单细胞样品的读数; 将每个单个细胞样本的读数分别对准参考基因组的序列，并对所述读取执行数据过滤; 基于经过滤的读数，确定每个单细胞样品的一致的基因型，其中所有单细胞样品的一致基因型构成所述组的SNP数据集; 针对所述每个单细胞，基于所述组的SNP数据集，在对应于参照基因组的SNP数据集中的位置的位点处确定每个细胞的相应基因型; 并选择与细胞突变相关的SNP位点，并且基于所述单细胞在所述位点处的基因型，对所述单细胞进行分类。

    Entropy decoding methods and apparatus using most probable and least probable signal cases
    7.
    发明授权
    Entropy decoding methods and apparatus using most probable and least probable signal cases 有权
    使用最可能和最不可能的信号情况的熵解码方法和装置

    公开(公告)号：US08749409B2

    公开(公告)日：2014-06-10

    申请号：US13113918

    申请日：2011-05-23

    申请人： Xun Xu

    发明人： Xun Xu

    IPC分类号： H03M7/00

    CPC分类号： H03M7/4018

    摘要： An entropy decoding apparatus may include a data structure stored in memory. The data structure may include a decoding engine vector or context engine vector. The decoding engine vector many have a first set of bits representing a value corresponding to a state of a coding engine, a second set of bits representing an offset value, and a third set of bits representing the contents of an input stream buffer. The context vector may have a first set of bits representing an addresses of a context most probable state, a second set of bits representing a plurality of possible values corresponding to a least probable symbol state of a coding engine, a third set of bits representing an addresses of a context least probable state, a fourth set of bits representing a binary most probable symbol value, and a fifth set of bits representing a binary least probable symbol value.

    摘要翻译： 熵解码装置可以包括存储在存储器中的数据结构。 数据结构可以包括解码引擎向量或上下文引擎向量。 解码引擎向量许多具有表示对应于编码引擎的状态的值的第一组比特，表示偏移值的第二比特组，以及表示输入流缓冲器的内容的第三组比特。 上下文矢量可以具有表示上下文最可能状态的地址的第一组位，表示与编码引擎的最小可能符号状态对应的多个可能值的第二组位，表示第一组位的第三组位 上下文最小可能状态的地址，表示二进制最可能符号值的第四组位，以及表示二进制最小可能符号值的第五组位。

    Superpixel segmentation methods and systems
    8.
    发明授权
    Superpixel segmentation methods and systems 有权
    超像素分割方法和系统

    公开(公告)号：US08472718B2

    公开(公告)日：2013-06-25

    申请号：US13204574

    申请日：2011-08-05

    申请人： Xutao Lv ,  Su Wang ,  Shengyang Dai ,  Xun Xu ,  Akira Nakamura

    发明人： Xutao Lv ,  Su Wang ,  Shengyang Dai ,  Xun Xu ,  Akira Nakamura

    IPC分类号： G06K9/34 ,  G06K9/00

    CPC分类号： G06T3/4053

    摘要： Systems and methods for implementing a superpixel image segmentation technique using a boundary preserving distance metric are disclosed. The disclosed technique segments a digital image into superpixels comprising contiguous pixel regions sharing similar characteristics. Superpixel image segmentation techniques presented herein utilize a boundary preserving distance metric. A boundary preserving distance metric presented herein measures the similarity between two pixels of a digital image at least partially based on a boundary probability values of the two pixels and surrounding pixels.

    摘要翻译： 公开了使用边界保留距离度量来实现超像素图像分割技术的系统和方法。 所公开的技术将数字图像分割成包含具有相似特征的相邻像素区域的超像素。 本文提出的超像素图像分割技术利用边界保留距离度量。 这里给出的边界保持距离度量至少部分地基于两个像素和周围像素的边界概率值来测量数字图像的两个像素之间的相似度。

    POLYPEPTIDE INHIBITING ANGIOGENESIS AND APPLICATION THEREOF
    9.
    发明申请
    POLYPEPTIDE INHIBITING ANGIOGENESIS AND APPLICATION THEREOF 有权
    多肽抑制血管生成及其应用

    公开(公告)号：US20110034387A1

    公开(公告)日：2011-02-10

    申请号：US12866166

    申请日：2008-02-04

    申请人： Hui Zhao ,  Xun Xu

    发明人： Hui Zhao ,  Xun Xu

    IPC分类号： A61K38/10 ,  C07K7/06 ,  C07K7/08 ,  C07H21/00 ,  A61K38/08 ,  A61P27/02 ,  A61P9/00

    CPC分类号： C07K14/775 ,  A61K38/00

    摘要： Provided is a low molecular polypeptide that can inhibit angiogenesis consisting of amino acid sequence YRGKKA, which is same to one portion sequence in apolipoprotein (a) Kringle V. Also provided are pharmaceutical composition and the uses for preventing or treating diseases relating to angiogenesis.

    摘要翻译： 本发明提供能够抑制血管发生的低分子多肽，其由氨基酸序列YRGKKA组成，其与载脂蛋白（a）Kringle V中的一部分序列相同。还提供了药物组合物和用于预防或治疗与血管发生有关的疾病的用途。