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公开(公告)号：US09896434B2
公开(公告)日：2018-02-20
申请号：US15301603
申请日：2015-04-02
申请人： SANOFI
发明人： Lothar Schwink , Christian Buning , Heiner Glombik , Matthias Gossel , Dieter Kadereit , Nis Halland , Matthias Lohmann , Christoph Pöverlein , Kurt Ritter
IPC分类号： C07D401/12 , A61K31/402 , A61K31/4439 , C07D207/26 , A61K45/06 , A61K31/5377 , A61K31/155 , C07D207/273
CPC分类号： C07D401/12 , A61K31/155 , A61K31/402 , A61K31/4439 , A61K31/5377 , A61K45/06 , C07D207/26 , C07D207/273 , A61K2300/00
摘要： The present invention relates to indanone compounds. The indanone compounds are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to the use of indanone compounds as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.
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公开(公告)号：US09908868B2
公开(公告)日：2018-03-06
申请号：US15284334
申请日：2016-10-03
申请人： SANOFI
发明人： Lothar Schwink , Christian Buning , Heiner Glombik , Matthias Gossel , Dieter Kadereit , Nis Halland , Matthias Lohmann , Christoph Pöverlein , Kurt Ritter
IPC分类号： C07D401/14 , C07D413/14 , C07D403/04 , C07D417/14 , A61K31/155 , A61K31/397 , A61K31/40 , A61K31/4035 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/517 , A61K31/702 , A61K45/06 , C07D405/14 , C07D471/04
CPC分类号： C07D401/14 , A61K31/155 , A61K31/397 , A61K31/40 , A61K31/4035 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/517 , A61K31/702 , A61K45/06 , C07D403/04 , C07D405/14 , C07D413/14 , C07D417/14 , C07D471/04
摘要： The present invention relates to isoindolinone compounds. The isoindolinone compounds are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to the use of isoindolinone compounds as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.
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公开(公告)号：US09758520B2
公开(公告)日：2017-09-12
申请号：US15284213
申请日：2016-10-03
申请人： SANOFI
发明人： Lothar Schwink , Christian Buning , Heiner Glombik , Matthias Gossel , Dieter Kadereit , Nis Halland , Matthias Lohmann , Christoph Pöverlein , Kurt Ritter
IPC分类号： C07D401/02 , C07D401/10 , C07D401/14 , A61K31/437 , A61K31/4353 , C07D471/04 , C07D231/56 , C07D249/18 , A61K45/06 , A61K31/4439 , A61K31/155 , A61K31/397 , A61K31/40 , A61K31/444 , A61K31/702
CPC分类号： C07D471/04 , A61K31/155 , A61K31/397 , A61K31/40 , A61K31/4439 , A61K31/444 , A61K31/702 , A61K45/06 , C07D231/56 , C07D249/18 , C07D401/14 , A61K2300/00
摘要： The present invention relates to substituted fused heterocyclic compounds.The substituted fused heterocyclic compounds are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to the use of substituted fused heterocyclic compounds as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.
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4.发明申请NOVEL SUBSTITUTED TETRAHYDRONAPHTHALENES, PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF AS MEDICAMENTS 审中-公开新型替代四氢萘，其制备方法及其作为药物的用途公开(公告)号：US20140088077A1
公开(公告)日：2014-03-27
申请号：US14094976
申请日：2013-12-03
申请人： SANOFI
IPC分类号： C07D405/12 , A61K31/4525 , A61K31/4709 , C07D307/12 , A61K45/06 , A61K31/541 , A61K31/496 , A61K31/397 , A61K31/553 , A61K31/55 , A61K31/4025 , A61K31/5377
CPC分类号： C07D405/12 , A61K31/397 , A61K31/4025 , A61K31/4525 , A61K31/4709 , A61K31/496 , A61K31/5377 , A61K31/541 , A61K31/55 , A61K31/553 , A61K45/06 , C07D307/12
摘要： The invention relates to substituted tetrahydronaphthalenes and derivatives thereof, and also to the physiologically compatible salts and physiologically functional derivatives thereof, to preparation thereof, to medicaments comprising at least one inventive substituted tetrahydronaphthalene or derivative thereof, and to the use of the inventive substituted tetrahydronaphthalenes and derivatives thereof as medicaments.
摘要翻译： 本发明涉及取代的四氢萘及其衍生物，以及其生理上相容的盐和生理功能衍生物及其制备方法，涉及包含至少一种本发明取代的四氢化萘或其衍生物的药物，以及本发明取代的四氢萘和 其衍生物作为药物。
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