公开(公告)号：US20240189257A1

公开(公告)日：2024-06-13

申请号：US18282672

申请日：2021-03-25

Applicant: SAMI-SABINSA GROUP LIMITED

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sarang Bani ,  Anjali Pandey

IPC: A61K31/12 ,  A61K31/37 ,  A61K31/7034 ,  A61K36/185 ,  A61K36/48 ,  A61P13/12

CPC classification number: A61K31/12 ,  A61K31/37 ,  A61K31/7034 ,  A61K36/185 ,  A61K36/48 ,  A61P13/12

Abstract: The invention discloses the use of a composition comprising 70%-80% w/w tetrahydrocurcuminoids, 10%-20% w/w hexahydrocurcuminoids and 5%-10% w/w octahydrocurcuminoids in the therapeutic management of nephropathy in mammals. The composition further comprises β-glucogallin and total mucic acid gallates, C-glucosides and tannins isolated from Pterocarpus marsupium. The invention also discloses the potential of the composition comprising β-glucogallin and total mucic acid gallates from Emblica officinalis, C-glucosides and tannins isolated from Pterocarpus marsupium in the therapeutic management of nephropathy.

公开(公告)号：US12053500B2

公开(公告)日：2024-08-06

申请号：US17644990

申请日：2021-12-17

Applicant: Sami-Sabinsa Group Limited

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Lakshmi Mundkur ,  A. Muhamad Ibrahim

IPC: A61K36/9066 ,  A23L33/105 ,  A61K9/00 ,  A61K9/20 ,  A61K9/48 ,  A61K31/12 ,  A61K31/19 ,  A61K31/23 ,  A61K36/324 ,  A61K47/12 ,  A61K47/26 ,  A61K47/42 ,  A61P3/06 ,  A61P19/02 ,  A61P39/06

CPC classification number: A61K36/9066 ,  A23L33/105 ,  A61K9/0053 ,  A61K9/0056 ,  A61K9/2009 ,  A61K9/2013 ,  A61K9/2054 ,  A61K9/2059 ,  A61K9/4866 ,  A61K31/12 ,  A61K31/19 ,  A61K31/23 ,  A61K36/324 ,  A61K47/12 ,  A61K47/26 ,  A61K47/42 ,  A61P3/06 ,  A61P19/02 ,  A61P39/06

Abstract: A composition enriched with bisdemethoxycurcumin standardized to contain 20-80% w/w bisdemethoxycurcumin, 10-35% w/w demethoxycurcumin and 10-50% w/w curcumin. More specifically the invention discloses the potential of a composition comprising 20-80% w/w bisdemethoxycurcumin, 10-35% w/w demethoxycurcumin and 10-50% w/w curcumin in the management of nephrotoxicity in mammals. The composition further comprises a Nigella sativa extract standardised to contain not less than 2% w/w thymoquinone and about 0.01%-10% w/w thymohydroquinone.

公开(公告)号：US20230381117A1

公开(公告)日：2023-11-30

申请号：US18265903

申请日：2021-12-16

Applicant: SAMI-SABINSA GROUP LIMITED

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Lakshmi Mundkur

IPC: A61K31/12 ,  A61K9/00 ,  A61P3/06

CPC classification number: A61K31/12 ,  A61K9/0053 ,  A61P3/06

Abstract: The present invention discloses methods and compositions for therapeutic management of obesity and high fat diet induced hyperlipidemia in mammals, using a composition comprising not less than 20% w/w bisdemethoxycurcumin, wherein the composition further comprises of 10-35% w/w demethoxycurcumin and 10-50% w/w curcumin.