公开(公告)号：US20240252514A1

公开(公告)日：2024-08-01

申请号：US18289550

申请日：2022-05-04

Applicant: SAGE THERAPEUTICS, INC.

Inventor： James J. Doherty ,  Michael C. Quirk ,  Aaron Michael Koenig ,  Jason Karl Johannesen

IPC: A61K31/575 ,  A61P25/16 ,  A61P25/28

CPC classification number: A61K31/575 ,  A61P25/16 ,  A61P25/28

Abstract: Provided herein are methods for improving working memory and/or executive function in a subject suffering from Parkinson's Disease, comprising administering to the subject a compound having the formula.

公开(公告)号：US20250064833A1

公开(公告)日：2025-02-27

申请号：US18719194

申请日：2022-12-13

Applicant: SAGE THERAPEUTICS, INC.

Inventor： Michael C. Quirk ,  Aaron Michael Koenig

IPC: A61K31/575 ,  A61K31/4365 ,  A61K31/4375 ,  A61K31/4439 ,  A61K31/454 ,  A61K31/4545 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/5025 ,  A61K31/517 ,  A61K31/519 ,  A61K31/538 ,  A61K31/58

Abstract: The present disclosure relates to compositions, kits, and methods of treating CNS diseases and disorders using a combination of a muscarinic receptor positive modulator and an NMDA receptor positive allosteric modulator.

公开(公告)号：US20250041317A1

公开(公告)日：2025-02-06

申请号：US18719143

申请日：2022-12-12

Applicant: SAGE THERAPEUTICS, INC.

Inventor： Michael C. Quirk ,  Aaron Michael Koenig

IPC: A61K31/575 ,  A61P25/28

Abstract: Provided herein are methods for improving working memory and/or executive function in a subject suffering from Huntington's Disease, comprising administering to the subject SAGE-718, an investigational positive allosteric modulator of the NMDA receptor.